Hyaluronic acid methacryloyl (MW 50000)  (Synonyms: HAMA (MW 50000))

Hyaluronic acid methacryloyl (HAMA) (MW 50000) is a methacrylate-modified hyaluronic acid that serves as a hydrogel former, hydrolysis-resistant material, photocrosslinkable hydrogel scaffold, and drug delivery carrier for tissue engineering. Hyaluronic acid methacryloyl (MW 50000) forms hydrogels via photocrosslinking; when combined with AuMA NPs through a one-step photocrosslinking method, its effective swelling ratio increases, and the mechanical reinforcement effect of Au NPs compensates for the impact caused by reduced crosslinking density. Hyaluronic acid methacryloyl (MW 50000) can be combined with AuMA NPs via a one-step photocrosslinking method, enabling non-invasive monitoring of hydrogel degradation with contrast-enhanced micro-CT^[1].

Hyaluronic acid methacryloyl (MW 50000) (5% w/v; 24 h-4 weeks) hydrogels prepared with 10 mM AuMA NPs via one-step photocrosslinking exhibit an increased effective swelling ratio compared to HAMA alone, but maintain comparable compressive modulus and hydrolytic stability over 4 weeks in vitro^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

50000 (Average)

Solid

White to off-white

[Hyaluronic acid methacryloyl (MW 50000)]

Room temperature in continental US; may vary elsewhere.

• [1]. Li L, et al. Methacrylate-Modified Gold Nanoparticles Enable Non-Invasive Monitoring of Photocrosslinked Hydrogel Scaffolds. Adv Nanobiomed Res. 2022;2(7):2200022.