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  3. Carbomer 940

Carbomer 940 (CBM 940) is an acrylic polymer with high viscosity, good thermal stability and histocompatibility. Carbomer 940 serves as a transdermal drug delivery carrier and an external gel matrix. Carbomer 940 has no cytotoxicity, and it can also improve blood supply in the stasis zone of burns and promote wound repair. Carbomer 940 is applicable to pharmaceutical research.

For research use only. We do not sell to patients.

Carbomer 940

Carbomer 940 Chemical Structure

CAS No. : 9007-20-9

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Based on 1 publication(s) in Google Scholar

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Description

Carbomer 940 (CBM 940) is an acrylic polymer with high viscosity, good thermal stability and histocompatibility. Carbomer 940 serves as a transdermal drug delivery carrier and an external gel matrix. Carbomer 940 has no cytotoxicity, and it can also improve blood supply in the stasis zone of burns and promote wound repair. Carbomer 940 is applicable to pharmaceutical research[1].

In Vitro

Carbomer 940 (24 h) shows no cytotoxicity to rat epithelial fibroblasts as determined by the MTT assay[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Carbomer 940 (1%; topical administration; 21 days; in the form of hydrogel) significantly improves blood supply in the stasis zone and prevents tissue necrosis in a rat skin burn model[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Wistar rats (male, adult, 300-350 g, full-thickness burn model)[1]
Dosage: 1%
Administration: topical; daily; up to 21 days; in the form of hydrogel
Result: Improved tissue perfusion in the burn stasis zone, reduced the area of necrotic tissue.
Had no cytotoxicity, and promoted epithelial regeneration, collagen deposition and fibroplasia in the stasis zone.
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[Carbomer 940]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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This equation is commonly abbreviated as: C1V1 = C2V2

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
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Working solution concentration: mg/mL
Purity & Documentation

Purity: 95.0%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Carbomer 940
Cat. No.:
HY-W250721A
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