Hyaluronic acid (MW 50000-100000)
Based on 1 Customer Validation
Hyaluronic acid (MW 50000-100000) (Hyaluronan (MW 50000-100000)) is a biopolymer composed of repeating units of disaccharides with a molecular weight of 50000-100000 Da. Hyaluronic acid (MW 50000-100000) can be used as a drug carrier for drug delivery.
For research use only. We do not sell to patients.
- CAS No.: 9004-61-9
- Formula: (C14H21NO11)n
- Molecular Weight:379.11 (monomer)
-
Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
Description
In Vitro
Hyaluronic acid (HA) is widely used in aesthetic medicine due to its binding ability with a large number of water molecules. It improves tissue hydration and their resistance to mechanical damage. HA plays an important role in wound healing, ovulation, fertilization, signal transduction, and tumor physiology. HA is used in joint diseases such as osteoarthritis or rheumatoid arthritis. HA of a high molecular mass reduces the chemotaxis and migration of inflammatory cells which acts as a good barrier to the inflammatory process and protects against the effects of free radicals. HA is used in ophthalmology due to its lubricating properties for the corneal endothelium, and improves tissue hydration and cellular resistance to mechanical damage in aesthetic dermatology, and has marginal adverse effects. Several trials indicate its role in tumor markers, liver diseases, and in pharmaceuticals[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 9004-61-9
-
Appearance Solid
-
Molecular Weight 379.11 (monomer)
-
Formula (C14H21NO11)n
-
SMILES
CO[C@H]1[C@H](O)[C@@H](CO)O[C@@H](O[C@H]2[C@@H]([C@H]([C@@H](O[C@H]2C(O)=O)OC)O)O)[C@@H]1NC(C)=O.[n]
-
Synonyms
Hyaluronan (MW 50000-100000); Hyaluronate (MW 50000-100000)
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
H2O : 100 mg/mL (Need ultrasonic)
Purity & Documentation
-
Data Sheet (272 KB)
-
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
[1]. Salwowska NM, et al. Physiochemical properties and application of hyaluronic acid: a systematic review. J Cosmet Dermatol. 2016 Dec;15(4):520-526. [Content Brief]
[2]. Kogan G, et al. Hyaluronic acid: a natural biopolymer with a broad range of biomedical and industrial applications. Biotechnol Lett. 2007 Jan;29(1):17-25. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)