Hyaluronic acid (MW 50000-100000)  (Synonyms: Hyaluronan (MW 50000-100000); Hyaluronate (MW 50000-100000))

Hyaluronic acid (MW 50000-100000) (Hyaluronan (MW 50000-100000)) is a biopolymer composed of repeating units of disaccharides with a molecular weight of 50000-100000 Da. Hyaluronic acid (MW 50000-100000) can be used as a drug carrier for drug delivery^[1][2].

Hyaluronic acid (HA) is widely used in aesthetic medicine due to its binding ability with a large number of water molecules. It improves tissue hydration and their resistance to mechanical damage. HA plays an important role in wound healing, ovulation, fertilization, signal transduction, and tumor physiology. HA is used in joint diseases such as osteoarthritis or rheumatoid arthritis. HA of a high molecular mass reduces the chemotaxis and migration of inflammatory cells which acts as a good barrier to the inflammatory process and protects against the effects of free radicals. HA is used in ophthalmology due to its lubricating properties for the corneal endothelium, and improves tissue hydration and cellular resistance to mechanical damage in aesthetic dermatology, and has marginal adverse effects. Several trials indicate its role in tumor markers, liver diseases, and in pharmaceuticals^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

379.11 (monomer)

(C₁₄H₂₁NO₁₁)n

9004-61-9

Solid

CO[C@H]1[C@H](O)[C@@H](CO)O[C@@H](O[C@H]2[C@@H]([C@H]([C@@H](O[C@H]2C(O)=O)OC)O)O)[C@@H]1NC(C)=O.[n]

Room temperature in continental US; may vary elsewhere.

Store at room temperature 3 years

• [1]. Salwowska NM, et al. Physiochemical properties and application of hyaluronic acid: a systematic review. J Cosmet Dermatol. 2016 Dec;15(4):520-526.  [Content Brief]

  [2]. Kogan G, et al. Hyaluronic acid: a natural biopolymer with a broad range of biomedical and industrial applications. Biotechnol Lett. 2007 Jan;29(1):17-25.  [Content Brief]