Hyaluronic acid (Mw:1000-2000Da)
Based on 1 Customer Validation
Hyaluronic acid (Mw: 1000-2000 Da) is a long-chain unbranched polysaccharide with a molecular weight of 1000-2000 Da. Hyaluronic acid (Mw: 2000 Da) inhibits IL-1β expression and increases LC3-II. Hyaluronic acid (Mw: 1000-2000Da) can regulate tissue homeostasis and stress resistance, promote angiogenesis and tissue remodeling. Hyaluronic acid (Mw: 1000-2000 Da) has good biocompatibility and biodegradability, and can be used in drug delivery systems and tissue engineering. Hyaluronic acid (Mw: 2000 Da) can reduce facial skin blemishes and sagging.
For research use only. We do not sell to patients.
- CAS No.: 9004-61-9
- Formula: (C14H21NO11)n
- Molecular Weight:1000-2000
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
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IL-1β |
Hyaluronic acid (Mw:1000-2000Da) (2 kDa; 1-100 μg/mL; 48 h) inhibits the increase in inflammatory cytokine gene expression levels (TNF-α and IL-1β mRNA) and improves cell viability in H2O2-treated NHEK cells[2].
Hyaluronic acid (Mw:1000-2000Da) (2 kDa; 10-100 μg/mL; 48 h) significantly increases the cell viability of NHEK cells after UVB stimulation and increases LC3-II in NHEK cells irradiated with UVB[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Normal human epidermal keratinocytes (NHEK)
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Concentration:0.1 μg/mL, 1 μg/mL, 10 μg/mL, 100 μg/mL
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Incubation Time:24 h, 72 h (for cell viability evaluation in unstimulated cells); 48 h (for cell viability evaluation in stimulated cells)
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Result:Showed no significant difference in cell viability after 24 h and 72 h (unstimulated NHEK cells).
Showed higher, and concentration-dependent cell viability than the control group after 1 μM H2O2 stimulation.
Showed higher cell viability than the control group after UVB stimulation (10 μg/mL and 100 μg/mL).
Chemical Information
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CAS No. 9004-61-9
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Appearance Solid
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Molecular Weight 1000-2000
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Formula (C14H21NO11)n
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Color White to off-white
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SMILES
CO[C@H]1[C@H](O)[C@@H](CO)O[C@@H](O[C@H]2[C@@H]([C@H]([C@@H](O[C@H]2C(O)=O)OC)O)O)[C@@H]1NC(C)=O.[n]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
H2O : 40 mg/mL (ultrasonic and warming and heat to 60°C)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)