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RSV Inhibitor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	RSV (72) 5-HT Receptor (1) Angiotensin-converting Enzyme (ACE) (1) Apoptosis (2) Bacterial (1) Biochemical Assay Reagents (1) Calcium Channel (1) CRM1 (1) DNA/RNA Synthesis (7) Drug Metabolite (3) Enterovirus (2) Environmental Pollutants (1) Filovirus (1) Fluorescent Dye (3) HCV (3) HIV (4) HSV (1) IFNAR (2) IGF-1R (1) Influenza Virus (7) Isotope-Labeled Compounds (1) Lactate Dehydrogenase (1) MDM-2/p53 (1) NF-κB (1) Reference Standards (5) Reverse Transcriptase (3) SARS-CoV (4) Small Interfering RNA (siRNA) (2) β-glucuronidase (1)
By Research Areas:	Cancer (6) Endocrinology (2) Infection (78) Inflammation/Immunology (3) Metabolic Disease (3)
Oligonucleotides:	siRNA drugs (2) siRNAs (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Targets Recommended: RSV

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-104032

Ac-CoA Synthase-IN-1 5+ Cited Publications	RSV	Infection Metabolic Disease
Ac-CoA Synthase-IN-1 is a potent, reversible acetate-dependent acetyl-CoA synthetase 2 (ACSS2) inhibitor with an IC₅₀ of 0.6 μM . Ac-CoA Synthase-IN-1 inhibits the respiratory syncytial virus (RSV) .

HY-N6771

Cyclopiazonic acid 5+ Cited Publications	Calcium Channel 5-HT Receptor MDM-2/p53 Apoptosis RSV	Infection
Cyclopiazonic acid is an endoplasmic reticulum calcium ATPase (ECAs) inhibitor and human respiratory syncytial virus (RSV) inhibitor (EC₅₀ value of 4.13 μ M), which can reduce the antagonistic effect of 5-HT receptors in rat thoracic aorta, induce p53 dependent cell apoptosis and reproductive toxicity in mouse testes, and inhibit the biological activation of aflatoxin B ^[1][4][5].

HY-W251428

Phosphatidylglycerols (egg) sodium salt Egg PG	Biochemical Assay Reagents	Others
Phosphatidylglycerols (PG) is a selective inhibitor targeting the TLR4 accessory protein CD14/MD-2 complex, inhibiting LPS or virus (such as RSV)-mediated inflammatory signaling pathways through competitive binding. Phosphatidylglycerols directly bind to viral particles to block infection, inhibit COX-2 expression to reduce the release of inflammatory factors (IL-6, IL-8), and improve oxidative stress by regulating mitochondrial membrane phospholipid remodeling. Phosphatidylglycerols can be taken orally or by inhalation and can be used in the study of chronic inflammatory diseases (such as atherosclerosis) and respiratory viral infections (such as RSV) .

HY-146246

EIDD-2749 5 Publications Verification 4'-FlU; 4'-Fluorouridine	RSV SARS-CoV HCV	Infection
EIDD-2749 (4'-Fluorouridine) is an orally active RdRp inhibitor. EIDD-2749 effectively blocks the replication of *RSV* and SARS-CoV-2. EIDD-2749 also exhibits activity against HCV and lymphocytic choriomeningitis virus (LCMV). EIDD-2749 is a promising oral therapeutic candidate for COVID-19 and is also suitable for research on other RNA viruses .

HY-126303C

GS-443902 trisodium Maximum Cited Publications 13 Publications Verification GS-441524 triphosphate trisodium; Remdesivir metabolite trisodium	DNA/RNA Synthesis SARS-CoV RSV HCV Drug Metabolite	Infection
GS-443902 trisodium (GS-441524 triphosphate trisodium) is a potent viral RNA-dependent RNA-polymerases (RdRp) inhibitor with IC₅₀s of 1.1 μM, 5 μM for *RSV* RdRp and HCV RdRp, respectively. GS-443902 trisodium is the active triphosphate metabolite of Remdesivir (GS-5734) .

HY-109142

Ziresovir 5 Publications Verification AK0529; RO-0529	RSV	Infection
Ziresovir (AK0529;RO-0529) is a potent, selective, and orally bioavailable respiratory syncytial virus (RSV) fusion (F) protein (RSV F) protein inhibitor. Ziresovir shows anti-RSV activity (EC₅₀=3 nM) and highlights pharmacokinetics in animal species .

HY-16727

Presatovir 5+ Cited Publications GS-5806	RSV	Infection
Presatovir (GS-5806) is an orally bioavailable *RSV* fusion inhibitor with a mean EC₅₀ value of 0.43 nM .

HY-147346

Zelicapavir 1 Publications Verification EDP-938; RSV-IN-7	RSV	Infection
Zelicapavir (RSV-IN-7) (example 253) is an orally active *RSV* inhibitor (EC₅₀: < 0.4 μΜ) .

HY-15970

Verdinexor 2 Publications Verification KPT-335	CRM1 Apoptosis RSV	Infection Inflammation/Immunology Cancer
Verdinexor (KPT-335) is an orally active inhibitor for *selective inhibitor* of nuclear export (SINE*). Verdinexor inhibits* the respiratory syncytial virus A2 (RSV A2) replication with an IC₅₀ of 0.96 µM. Verdinexor inhibits the function of nuclear export protein Exportin 1 (XPO1/CRM1), inhibiting pro-inflammatory responses. Verdinexor exhibits antitumor effciency .

HY-123475A

Sisunatovir hydrochloride 4 Publications Verification RV521 hydrochloride	RSV	Infection
Sisunatovir (RV521) hydrochloride is a potent and orally active respiratory syncytial virus (RSV) inhibitor with IC₅₀ values of 1.4, 1.0 nM for RSV A, RSV B, respectively. Sisunatovir hydrochloride inhibits RSV infection and reduces virus titers in the lungs of mice .

HY-123475

Sisunatovir 4 Publications Verification RV521	RSV	Infection
Sisunatovir (RV521) is a potent and orally active respiratory syncytial virus (RSV) inhibitor with IC₅₀ values of 1.4, 1.0 nM for RSV A, RSV B, respectively. Sisunatovir inhibits RSV infection and reduces virus titers in the lungs of mice .

HY-12993

RSV604 2 Publications Verification A-60444	RSV	Infection
RSV604 (A-60444) is an inhibitor of respiratory syncytial virus (RSV) replication. RSV604 targets the nucleocapsid protein, with a K_d of 1.6 μM. RSV604 displays submicromolar activity against numerous clinical isolates of both the A and B subtypes of RSV (average EC₅₀s=0.8 μM) .

HY-102038

PC786 2 Publications Verification	RSV	Infection
PC786 is an inhaled respiratory syncytial virus (RSV) L protein polymerase inhibitor. PC786 demonstrates potent antiviral activity against *RSV-A* (IC₅₀ <0.09 to 0.71 nM) and *RSV-B* (IC₅₀, 1.3 to 50.6 nM) .

HY-12983

ALS-8112 3 Publications Verification	RSV	Infection
ALS-8112 is a potent and selective respiratory syncytial virus (RSV) polymerase inhibitor. The 5'-triphosphate form of ALS-8112 inhibits RSV polymerase with an IC₅₀ of 0.02 μM.

HY-121075

Alizarin complexone	Fluorescent Dye Reverse Transcriptase HIV RSV	Infection Endocrinology Cancer
Alizarin complexone is a calcium-binding fluorescent dye. Alizarin complexone stains mineralized areas of bone by binding to calcium crystals. Alizarin complexone inhibits the reverse transcriptase activity of RAV-2, HIV-1, and *RSV* with IC₅₀ values of 3.8 μg/mL, 45 μg/mL, and 100 μg/mL, respectively. Alizarin complexone exhibits antiviral activity against HIV-1 and RSV. Alizarin complexone delays RSV-induced tumor induction in chickens .

HY-112180

Rilematovir 5 Publications Verification JNJ-678; JNJ-53718678	RSV	Infection
Rilematovir (JNJ-678) is a novel fusion protein inhibitor. Rilematovir has the potential for respiratory syncytial virus (RSV) research.

HY-149648

JNJ-8003	RSV DNA/RNA Synthesis	Infection
JNJ-8003 is a potent and orally active non-nucleoside RSV polymerase inhibitor with an IC₅₀ of 0.29 nM. JNJ-8003 targets the L protein polymerase complex of RSV (IC₅₀ = 0.67 nM), and blocks the transcription and replication of the viral genome by inhibiting the activity of RNA-dependent RNA polymerase (RdRp). JNJ-8003 displays subnanomolar activity in vitro as well as prominent efficacy in mice and a neonatal lamb models. JNJ-8003 can be used for the study of respiratory syncytial virus (RSV) .

HY-11097

TMC353121 5+ Cited Publications	RSV	Infection
TMC353121 is a potent respiratory syncytial virus (RSV) fusion inhibitor with pEC₅₀ of 9.9.

HY-122587

AVG-233	DNA/RNA Synthesis RSV	Infection
AVG-233 is a potent, orally active RNA dependent RNA polymerase (RdRp) inhibitor. AVG-233 prevents initiation of the viral polymerase complex at the promoter. AVG-233 binding site is present in the L_1-1749 fragment. AVG-233 has nanomolar activity against both RSV strains and clinical RSV isolates (EC₅₀=0.14-0.31 μM). AVG-233 can be used for research of respiratory syncytial virus (RSV) .

HY-126303

GS-443902 GS-441524 triphosphate; Remdesivir metabolite	DNA/RNA Synthesis SARS-CoV RSV HCV Drug Metabolite	Infection
GS-443902 (GS-441524 triphosphate) is a potent viral RNA-dependent RNA-polymerases (RdRp) inhibitor with IC₅₀s of 1.1 µM, 5 µM for *RSV* RdRp and HCV RdRp, respectively. GS-443902 is the active triphosphate metabolite of Remdesivir .

HY-W013403

2'-Deoxy-2'-fluorouridine	IFNAR	Infection
2'-Deoxy-2'-fluorouridine is a derivative of the pyrimidine nucleoside uridine. 2'-Deoxy-2'-fluorouridine is a nucleoside analog that inhibits the replication of wild-type viruses by binding to the viral RNA. Hepatitis C polyU/UC RNA strands containing 2'-Deoxy-2'-fluorouridine, bind to RIG-I but do not activate RIG-I signaling in a reporter assay using Huh7 cells. 2'-Deoxy-2'-fluorouridine also has been used as a starting material in the synthesis of respiratory syncytial virus (RSV) polymerase inhibitors. 2'-Deoxy-2'-fluorouridine can incorporate into DNA and RNA in rat and woodchuck model upon administration. 2'-Deoxy-2'-fluorouridine can be studied in anti-viral research .

HY-12983A

Lumicitabine 1 Publications Verification ALS-008176; ALS-8176	RSV	Infection
Lumicitabine (ALS-008176) is an inhibitor of the respiratory syncytial virus (RSV) polymerase.

HY-W013605A

4-Methoxycinnamaldehyde 2 Publications Verification p-Methoxycinnamaldehyde	Environmental Pollutants RSV	Infection
4-Methoxycinnamaldehyde (p-Methoxycinnamaldehyde), an active constituent of Agastache rugosa, exhibits cytoprotective activity against respiratory syncytial virus (RSV) in human larynx carcinoma cell line. 4-Methoxycinnamaldehyde effectively inhibits cytopathic effect of RSV with an estimated IC₅₀ of 0.055 μg/mL .

HY-156442

MEDS433	Lactate Dehydrogenase	Infection
MEDS433 is a potent inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC₅₀ of 1.2 nM. MEDS433 exerts a potent antiviral activity against RSV-A and RSV-B in the one-digit nanomolar range. MEDS433 induces the expression of antiviral proteins encoded by interferon stimulated genes (ISGs) able to reduce RSV replication .

HY-158824A

Asvasiran sodium ALN-RSV01 sodium	Small Interfering RNA (siRNA) RSV	Infection
Asvasiran sodium is a siRNA that targets the respiratory syncytial virus (RSV) N gene and inhibits viral replication.

HY-120632

BMS-433771	RSV	Infection
BMS-433771 is a potent orally active inhibitor of respiratory syncytial virus (RSV). BMS-433771 is active against both A and B groups of RSV, with an average EC₅₀ of 20 nM. BMS-433771 can be used for the research of respiratory tract disease .

HY-12994

VP-14637 MDT-637	RSV	Infection
MDT-637 (VP 14637) is a novel *respiratory syncytial virus (RSV) fusion* inhibitor with an IC₅₀ of 1.42 ng/mL.

HY-124512

Quercetin pentaacetate Pentaacetylquercetin	RSV	Infection Inflammation/Immunology
Quercetin pentaacetate could interact with F-protein with lower binding energy and better stability to block viral adhesion. Quercetin pentaacetate interacts with RSV and inhibit the viral adhesion on cell surface .

HY-115574

RSV L-protein-IN-1	RSV	Infection
RSV L-protein-IN-1 (compound D) is a potent inhibitor of Respiratory syncytial virus (RSV) (EC₅₀=0.021 μM). RSV L-protein-IN-1 inhibits Polymerase (IC₅₀=0.089 μM)，and blocks RSV mRNA synthesis by inhibiting guanylation of viral transcripts. RSV L-protein-IN-1 shows moderate cytotoxicity (CC50=8.4 μM，HEp-2)，also exhibits activity and lowers virus titers in mouse models of RSV infection .

HY-143494

RSV/IAV-IN-3	RSV Influenza Virus	Infection
RSV/IAV-IN-3 (compound 14'i) is a dual inhibitor of respiratory syncytial virus (RSV) and influenza A virus (IAV) with EC₅₀ values of 2.92 µM and 1.90 µM,respectively. RSV/IAV-IN-3 has antiviral effect against H1N1 and H3N2 with EC₅₀ values of 3.25 µM and 1.50 µM in MDCK cells, respectively. RSV/IAV-IN-3 significantly inhibits the activity of luciferase in a dose-dependent manner, with an EC₅₀ of 3.89 µM. RSV/IAV-IN-3 inhibits IAV infectivity and RdRp activity. RSV/IAV-IN-3 inhibits IAV and RSV replication at the post-entry stage .

HY-112673

RSV-IN-1	RSV	Infection
RSV-IN-1 is a human respiratory syncytical virus (hRSV) inhibitor, with an IC₅₀ of 0.11 μM.

HY-109004

Enzaplatovir BTA-C585	RSV	Infection
Enzaplatovir (BTA-C585) is an orally bioavailable Inhibitor for respiratory syncytial virus (RSV) infection .

HY-12993B

RSV604 (R enantiomer) A-60444 (R enantiomer)	RSV	Infection
RSV604 R enantiomer is the R-enantiomer of RSV604. RSV604 is an inhibitor of respiratory syncytial virus (RSV) replication. R-enantiomer is less active against RSV.

HY-P991690

Glarivibart	RSV	Infection
Glarivibart is a humanized IgG1κ monoclonal antibody inhibitor targeting Respiratory syncytial virus (RSV) fusion F protein (RSV-F). Glarivibart has significant antiviral activity. Glarivibart can be used for RSV infections research .

HY-111296

YM 53403	RSV	Infection
YM 53403 is an anti-respiratory syncytial virus (RSV) agent, with an EC₅₀ of 0.20 μM. YM 53403 potently inhibits the replication of RSV strains belonging to both A and B subgroups .

HY-161771

JNJ-7184	RSV	Infection
JNJ-7184 is a non-nucleoside inhibitor of the *RSV*-Large (L) polymerase, with the pEC₅₀ and pCC₅₀ of 7.86 and 4.29 in Hela cells, respectively. JNJ-7184 prevents *RSV* replication and transcription by inhibiting initiation or early elongation .

HY-138956

MAY0132	NF-κB RSV	Infection
MAY0132 is a potent and selective EPAC2 inhibitor with an IC₅₀ of 0.4 μM. MAY0132 significantly inhibits replication of HMPV, AdV and *RSV, reduces viral infection-induced cytokine/chemokine production, and inhibits* NF-κB activation. MAY0132 has antiviral activity and can be used in the study of respiratory virus infection .

HY-173189B

2-5A TEA 2′,5′-ApApA TEA; 2′,5′-trioligoadenylate TEA; 5'-O-Triphosphoryladenylyl-(2'→5')-adenylyl-(2'→5')-adenosine TEA	RSV DNA/RNA Synthesis	Infection Inflammation/Immunology Cancer
2-5A (2′,5′-ApApA; 2′,5′-trioligoadenylate; 5'-O-Triphosphoryladenylyl-(2'→5')-adenylyl-(2'→5')-adenosine) TEA is a 5'-triphosphorylated (2',5') oligoadenylate. 2-5A TEA is an immunotransmitter that fuels RNase L immunity. 2-5A TEA degrades viral mRNA and inhibits protein synthesis by binding to RNase L and activating its endoribonuclease activity. 2-5A TEA can be used in *RSV* and cancer research .

HY-171983

RSV-IN-13	RSV	Infection
RSV-IN-13 (compound 24) is a selective *RSV* fusion protein inhibitor with antiviral activity. RSV-IN-13 has an EC₅₀ of 444.2 nM against RSV A2 strain and a CC₉₀ of 23.7 μM in HepG2 cells. RSV-IN-13 can block the virus from entering host cells. RSV-IN-13 can be used to study RSV infection .

HY-114721

BTA-9881 MEDI-564	RSV	Infection
BTA-9881 (MEDI-564) is a *RSV* inhibitor, with an EC₅₀: 48 nM, 59 nM and 160 nM for RSV A2, RSV Long, and RSV B1. BTA-9881 has favorable pharmacokinetics property .

HY-154964

RSV L-protein-IN-2	RSV	Infection
RSV L-protein-IN-2 (Compound A) is a noncompetitive RSV polymerase inhibitor (IC₅₀: 4.5 μM). RSV L-protein-IN-2 shows antiviral activity against long RSV strains (EC₅₀: 1.3 μM) .

HY-178151

CGR-50	RSV	Infection
CGR-50 is a potent RSV fusion glycoprotein (F protein) inhibitor (EC₅₀ = 32.6 nM against RSV A2 in HEp-2 cells). CGR-50 blocks RSV entry by binding to the F protein and inhibiting membrane fusion. CGR-50 can be used for RSV infection research .

HY-168616

CL-A3-7	RSV IGF-1R	Infection
CL-A3-7 is a virus-cell fusion inhibitor targeting the *RSV* F protein. It exerts its effect by blocking the interaction between the virus and the host IGF1R, effectively inhibiting infections of both wild-type *RSV* and the K394R variant. It is applicable to anti-RSV drug development and resistance-related research .

HY-124052

AZ-27	RSV	Infection
AZ-27 is a respiratory syncytial virus (RSV) inhibitor. AZ-27 can differentially suppress various *RSV* polymerase activities at the promoter, thereby inhibiting the early stages of mRNA transcription and genome replication by targeting the promoter .

HY-11098

JNJ 2408068 R170591	RSV	Infection
JNJ 2408068 is a potent *RSV* (respiratory syncytial virus) inhibitor. JNJ 2408068 significantly inhibits replication of RSV A and B subtypes in the lungs of cotton rats without any evidence of toxicity. The minimum protective dose of JNJ 2408068 appears to be approximately 0.39 mg/kg .

HY-158824

Asvasiran ALN-RSV01	Small Interfering RNA (siRNA) RSV	Infection
Asvasiran is a siRNA that targets the respiratory syncytial virus (RSV) N gene and inhibits viral replication.

HY-19874

RFI-641	RSV	Infection
RFI-641 is a selective inhibitor of the respiratory syncytial virus (RSV), with an IC₅₀ of 50 nM. RFI-641 inhibit binding and fusion of enveloped virus via interaction with the viral fusion protein .

HY-170395

GHP-88309	RSV DNA/RNA Synthesis	Infection
GHP-88309 is a broad-spectrum, orally active antiviral agent targeting paramyxoviruses, that targets the viral polymerase, interupts the viral RNA synthesis, and inhibits respiratory syncytial virus (RSV), measles virus (MeV), and canine distemper virus (CDV) with EC₅₀ of 0.06-1.2 μM. GHP-88309 exhibits anti-infectious efficacy in mouse models .

HY-N17236

Forsyshiyanine A	β-glucuronidase Influenza Virus RSV	Infection
Foryshiyanine A is a triterpenoid alkaloid. Foryshiyanine A possesses anti-inflammatory activity, inhibiting the release of β-glucuronidase from rat polymorphonuclear leukocytes. Foryshiyanine A exhibits antiviral activity, with an EC₅₀ of 4.5 μM against respiratory syncytial virus (RSV) and an IC₅₀ of 7.3 μM against influenza A virus (H1N1). Foryshiyanine A reduces viral load by disrupting viral replication and entry. Foryshiyanine A may be used for the researches of inflammation and infection .

HY-N15215

Antiviral agent 64	Enterovirus Influenza Virus RSV HSV	Infection Cancer
Antiviral agent 64 (Compound 12) is a diarylheptanoid that can be isolated from Alpinia officinarum. Antiviral agent 64 exhibits cytotoxicity in human neuroblastoma cell IMR-32 with an IC₅₀ of 0.23 μM. Antiviral agent 64 exhibits antiviral efficacy, that inhibits *RSV, poliovirus, measles virus, HSV-1, and influenza virus H1N1, with EC₅₀* of 13.3, 3.7, 6.3, 5.7, and <10 μg/mL, respectively .

Cat. No.	상품명	Type

HY-W251428

Phosphatidylglycerols (egg) sodium salt

Egg PG

Biochemical Assay Reagents

Phosphatidylglycerols (PG) is a selective inhibitor targeting the TLR4 accessory protein CD14/MD-2 complex, inhibiting LPS or virus (such as RSV)-mediated inflammatory signaling pathways through competitive binding. Phosphatidylglycerols directly bind to viral particles to block infection, inhibit COX-2 expression to reduce the release of inflammatory factors (IL-6, IL-8), and improve oxidative stress by regulating mitochondrial membrane phospholipid remodeling. Phosphatidylglycerols can be taken orally or by inhalation and can be used in the study of chronic inflammatory diseases (such as atherosclerosis) and respiratory viral infections (such as RSV) .

HY-W320523

ALizarin complexone dihydrate

Biochemical Assay Reagents

ALizarin complexone dihydrate is the dehydrate of Alizarin complexone (HY-121075). Alizarin complexone is a calcium-binding fluorescent dye. Alizarin complexone stains mineralized areas of bone by binding to calcium crystals. Alizarin complexone inhibits the reverse transcriptase activity of RAV-2, HIV-1, and RSV with IC₅₀ values of 3.8 μg/mL, 45 μg/mL, and 100 μg/mL, respectively. Alizarin complexone exhibits antiviral activity against HIV-1 and RSV. Alizarin complexone delays RSV-induced tumor induction in chickens .

Cat. No.	상품명	Target	Research Area	Image

HY-P991690

Glarivibart	RSV	Infection
Glarivibart is a humanized IgG1κ monoclonal antibody inhibitor targeting Respiratory syncytial virus (RSV) fusion F protein (RSV-F). Glarivibart has significant antiviral activity. Glarivibart can be used for RSV infections research .

HY-P992175

ADI-14448	RSV	Infection
ADI-14448 is a *RSV* prefusion fusion glycoprotein inhibitor and HMPV fusion glycoprotein inhibitor, with a K_d of 3.8 × 10 ^-10 M for *RSV* preF. ADI-14448 binds to epitope III of *RSV* preF, thereby blocking viral infection. ADI-14448 neutralizes *RSV* subtype A and HMPV subtype A1. ADI-14448 can be used in studies related to respiratory syncytial virus infection and metapneumovirus infection .

Cat. No.	상품명	Category	Target	Chemical Structure

HY-N6771

Cyclopiazonic acid 5+ Cited Publications	Alkaloids Structural Classification Microorganisms Pyrrole Alkaloids Classification of Application Fields Other Diseases Disease Research Fields Indole Alkaloids Source Classification	Calcium Channel 5-HT Receptor MDM-2/p53 Apoptosis RSV
Cyclopiazonic acid is an endoplasmic reticulum calcium ATPase (ECAs) inhibitor and human respiratory syncytial virus (RSV) inhibitor (EC₅₀ value of 4.13 μ M), which can reduce the antagonistic effect of 5-HT receptors in rat thoracic aorta, induce p53 dependent cell apoptosis and reproductive toxicity in mouse testes, and inhibit the biological activation of aflatoxin B ^[1][4][5].

HY-W013605A

4-Methoxycinnamaldehyde 2 Publications Verification p-Methoxycinnamaldehyde	Infection Structural Classification Classification of Application Fields Araceae Ketones, Aldehydes, Acids Acorus gramineus Soland. Plants Disease Research Fields Source Classification	Environmental Pollutants RSV
4-Methoxycinnamaldehyde (p-Methoxycinnamaldehyde), an active constituent of Agastache rugosa, exhibits cytoprotective activity against respiratory syncytial virus (RSV) in human larynx carcinoma cell line. 4-Methoxycinnamaldehyde effectively inhibits cytopathic effect of RSV with an estimated IC₅₀ of 0.055 μg/mL .

HY-N17236

Forsyshiyanine A	Structural Classification Alkaloids Oleaceae Pyridine Alkaloids Forsythia suspensa (Thunb.) Vahl Plants Source Classification	β-glucuronidase Influenza Virus RSV
Foryshiyanine A is a triterpenoid alkaloid. Foryshiyanine A possesses anti-inflammatory activity, inhibiting the release of β-glucuronidase from rat polymorphonuclear leukocytes. Foryshiyanine A exhibits antiviral activity, with an EC₅₀ of 4.5 μM against respiratory syncytial virus (RSV) and an IC₅₀ of 7.3 μM against influenza A virus (H1N1). Foryshiyanine A reduces viral load by disrupting viral replication and entry. Foryshiyanine A may be used for the researches of inflammation and infection .

HY-N15215

Antiviral agent 64	Structural Classification Monophenols Phenols Alpinia officinarum Hance Plants Source Classification Zingiberaceae	Enterovirus Influenza Virus RSV HSV
Antiviral agent 64 (Compound 12) is a diarylheptanoid that can be isolated from Alpinia officinarum. Antiviral agent 64 exhibits cytotoxicity in human neuroblastoma cell IMR-32 with an IC₅₀ of 0.23 μM. Antiviral agent 64 exhibits antiviral efficacy, that inhibits *RSV, poliovirus, measles virus, HSV-1, and influenza virus H1N1, with EC₅₀* of 13.3, 3.7, 6.3, 5.7, and <10 μg/mL, respectively .

HY-W013605AR

4-Methoxycinnamaldehyde (Standard) p-Methoxycinnamaldehyde (Standard)	Araceae Ketones, Aldehydes, Acids Acorus gramineus Soland. Plants Source Classification	Reference Standards RSV
4-Methoxycinnamaldehyde (Standard) is the analytical standard of 4-Methoxycinnamaldehyde. This product is intended for research and analytical applications. 4-Methoxycinnamaldehyde (p-Methoxycinnamaldehyde), an active constituent of Agastache rugosa, exhibits cytoprotective activity against respiratory syncytial virus (RSV) in human larynx carcinoma cell line. 4-Methoxycinnamaldehyde effectively inhibits cytopathic effect of RSV with an estimated IC50 of 0.055 μg/mL[1].

Cat. No.	상품명	Chemical Structure

HY-W013403S

2'-Deoxy-2'-fluorouridine-d2

2'-Deoxy-2'-fluorouridine-d₂ is the deuterium labeled 2'-Deoxy-2'-fluorouridine . 2'-Deoxy-2'-fluorouridine is a derivative of the pyrimidine nucleoside uridine. 2'-Deoxy-2'-fluorouridine is a nucleoside analog that inhibits the replication of wild-type viruses by binding to the viral RNA. Hepatitis C polyU/UC RNA strands containing 2'-Deoxy-2'-fluorouridine, bind to RIG-I but do not activate RIG-I signaling in a reporter assay using Huh7 cells. 2'-Deoxy-2'-fluorouridine also has been used as a starting material in the synthesis of respiratory syncytial virus (RSV) polymerase inhibitors. 2'-Deoxy-2'-fluorouridine can incorporate into DNA and RNA in rat and woodchuck model upon administration. 2'-Deoxy-2'-fluorouridine can be studied in anti-viral research .

HY-N6771S

Cyclopiazonic acid-13C20

Cyclopiazonic acid- ¹³C₂₀ is the ¹³C-labeled Cyclopiazonic acid (HY-N6771). Cyclopiazonic acid is an endoplasmic reticulum calcium ATPase (ECAs) inhibitor and human respiratory syncytial virus (RSV) inhibitor (EC₅₀ value of 4.13 μ M), which can reduce the antagonistic effect of 5-HT receptors in rat thoracic aorta, induce p53 dependent cell apoptosis and reproductive toxicity in mouse testes, and inhibit the biological activation of aflatoxin B .

Cat. No.	상품명		Classification

HY-158824A

Asvasiran sodium ALN-RSV01 sodium		siRNAs siRNA drugs
Asvasiran sodium is a siRNA that targets the respiratory syncytial virus (RSV) N gene and inhibits viral replication.

HY-158824

Asvasiran ALN-RSV01		siRNAs siRNA drugs
Asvasiran is a siRNA that targets the respiratory syncytial virus (RSV) N gene and inhibits viral replication.

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RSV Inhibitor

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