RSV/IAV-IN-2
RSV/IAV-IN-2 (compound 14c) is a potent and dual inhibitor of RSV/IAV. RSV/IAV-IN-2 has lesser cytotoxicity than the clinical agent, Ribavirin. RSV/IAV-IN-2 has the potential for the research of RSV and/or IAV infections.
For research use only. We do not sell to patients.
- CAS No.: 2395007-75-5
- Formula: C19H20N2O3S
- Molecular Weight:356.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK-293T | CC50 |
>100 μM
Compound: 14'c
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Cytotoxicity against HEK293T cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay
Cytotoxicity against HEK293T cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay
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[PMID: 31734025] |
| HEp-2 | CC50 |
1828 μM
Compound: 14'c
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Cytotoxicity against human HEp-2 cells assessed as reduction in cell viability measured after 48 hrs by MTS assay
Cytotoxicity against human HEp-2 cells assessed as reduction in cell viability measured after 48 hrs by MTS assay
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[PMID: 31734025] |
| HEp-2 | EC50 |
4.82 μM
Compound: 14'c
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Antiviral activity against GFP-fused wild-type RSV subgroup A Long infected in human HEp-2 cells measured 24 to 72 hrs post infection by fluorescence assay
Antiviral activity against GFP-fused wild-type RSV subgroup A Long infected in human HEp-2 cells measured 24 to 72 hrs post infection by fluorescence assay
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[PMID: 31734025] |
Chemical Information
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CAS No. 2395007-75-5
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Molecular Weight 356.44
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Formula C19H20N2O3S
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SMILES
CCOC1=CC=CC=C1NC(CSC2=CNC3=C2C=C(OC)C=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
H2O : 100 mg/mL (280.55 mM; Need ultrasonic)
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.8055 mL | 14.0276 mL | 28.0552 mL | 70.1380 mL |
| 5 mM | 0.5611 mL | 2.8055 mL | 5.6110 mL | 14.0276 mL | |
| 10 mM | 0.2806 mL | 1.4028 mL | 2.8055 mL | 7.0138 mL | |
| 15 mM | 0.1870 mL | 0.9352 mL | 1.8703 mL | 4.6759 mL | |
| 20 mM | 0.1403 mL | 0.7014 mL | 1.4028 mL | 3.5069 mL | |
| 25 mM | 0.1122 mL | 0.5611 mL | 1.1222 mL | 2.8055 mL | |
| 30 mM | 0.0935 mL | 0.4676 mL | 0.9352 mL | 2.3379 mL | |
| 40 mM | 0.0701 mL | 0.3507 mL | 0.7014 mL | 1.7535 mL | |
| 50 mM | 0.0561 mL | 0.2806 mL | 0.5611 mL | 1.4028 mL | |
| 60 mM | 0.0468 mL | 0.2338 mL | 0.4676 mL | 1.1690 mL | |
| 80 mM | 0.0351 mL | 0.1753 mL | 0.3507 mL | 0.8767 mL | |
| 100 mM | 0.0281 mL | 0.1403 mL | 0.2806 mL | 0.7014 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
RSV/IAV-IN-2 Related Classifications
HY-130627 Related Classifications
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