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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
78 Results for "
acidic-pH
" in MedChemExpress (MCE) Product Catalog:
Products (78)
78 Results for "acidic-pH" in MCE Product Catalog:
43
43 Publications Verification
Cat. No.: HY-P0014
CAS No.: 204656-20-2
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Neurological Disease Metabolic Disease Inflammation/Immunology
43
43 Publications Verification
Cat. No.: HY-P0014B
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5
Category:
Microorganisms Antibiotics Animal Husbandry Disease Research Antibacterial Disease Research Fields Other Antibiotics Cancer
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5
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Apramycin (Nebramycin II) is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin is a potential anti-drug-resistance antibiotic .
3
3 Cited Publications
Cat. No.: HY-P3462
CAS No.: 1415456-99-3
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3
3 Cited Publications
Cat. No.: HY-P3462A
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3
3 Cited Publications
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Lalistat 2 is an inhibitor of many lipases especially Lysosomal acid lipase (LAL, IC50 = 152 nM), which is a key enzyme that degrades neutral lipids at an acidic pH in lysosomes. Lalistat 2 is commonly used to investigate the cell-specific functions of LAL and LAL deficiency in vitro, as well as specifically measure LAL activity in human blood samples or cells .
2
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Deoxyribonuclease II (DNase II) is an endonuclease that hydrolyzes the phosphodiester bonds of deoxyribonucleotides in native and denatured DNA, producing 3' phosphate and 5'-hydroxyl termini. Deoxyribonuclease II works best at acidic pH and is commonly used in biochemical research .
1
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1
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1
1 Cited Publications
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Finafloxacin is an orally active fourth-generation fluoroquinolone broad-spectrum antibiotic. Finafloxacin exhibits stronger antibacterial activity in acidic pH environments and is not easily affected by bacterial multidrug efflux transporters. Finafloxacin is effective against a variety of extracellular pathogenic bacteria, and can also accumulate in macrophages, showing excellent antibacterial activity against intracellular Staphylococcus aureus, Listeria monocytogenes, Legionella pneumophila, Burkholderia pseudomallei, and other pathogens. Finafloxacin has been approved by the U.S. FDA for research on acute otitis externa mediated by Pseudomonas aeruginosa. Finafloxacin is also used in studies related to diseases such as melioidosis, inhalational tularemia, and inhalational plague .
1
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1
1 Cited Publications
Cat. No.: HY-P10218
CAS No.: 479482-23-0
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1
1 Cited Publications
Cat. No.: HY-P10218A
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1
1 Cited Publications
Cat. No.: HY-P10869
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Cat. No.: HY-P10272
CAS No.: 1628323-80-7
Synonyms: PTG-300
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Cat. No.: HY-W039911
CAS No.: 7493-95-0
Synonyms: PNP-alpHa-D-Gal; PNP-α-D-Gal
Cat. No.: HY-P4116
CAS No.: 2293160-09-3
Synonyms: pHLIP
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Cat. No.: HY-W111692
CAS No.: 68915-31-1
Cat. No.: HY-P0014S1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
