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3s-5r-5-aminotetrahydro-2h-pyran-3-ol-hydrochloride

" in MedChemExpress (MCE) Product Catalog:

標的別:	5-HT Receptor (4) Adrenergic Receptor (1) Akt (1) Amino Acid Decarboxylase (1) Amino Acid Derivatives (4) Antibiotic (2) Apoptosis (3) Autophagy (1) Bacterial (2) Biochemical Assay Reagents (10) Carbonic Anhydrase (1) Caspase (1) CDK (1) Cholinesterase (ChE) (2) COX (1) CRFR (1) DNA/RNA Synthesis (2) Dopamine Receptor (2) Drug Derivative (7) Drug Intermediate (11) Drug Metabolite (2) EGFR (1) Endogenous Metabolite (6) Environmental Pollutants (2) FKBP (1) Fungal (1) GnRH Receptor (1) HBV (1) HCV (1) Heme Oxygenase (HO) (2) Histone Methyltransferase (1) iGluR (2) Imidazoline Receptor (1) Isotope-Labeled Compounds (14) Lactate Dehydrogenase (1) Ligands for Target Protein for PROTAC (1) mAChR (3) MAP4K (1) Melanocortin Receptor (1) Mitochondrial Metabolism (1) Parasite (2) Phosphoramidites (2) PROTAC Linkers (5) PROTACs (1) Reactive Oxygen Species (ROS) (1) Reference Standards (11) Renin (1) Serotonin Transporter (1) Wnt (1) β-catenin (1)
研究分野別:	Cancer (20) Cardiovascular Disease (2) Endocrinology (3) Infection (3) Inflammation/Immunology (4) Metabolic Disease (1) Neurological Disease (15)
Oligonucleotides:	Other Phosphoramidite (2) Phosphoramidites (2)

100

阻害剤およびアゴニスト

生化学アッセイ試薬

ペプチド

天然物

同位体標識化合物

オリゴヌクレオチド

製品番号	製品名	Target	研究分野	構造式

HY-145514C

dTAGV-1 hydrochloride 5 Publications Verification	FKBP PROTACs	Cancer
dTAGV-1 hydrochloride is a potent and selective degrader of FKBP12 ^F36V-tagged proteins PROTAC degrader. dTAGV-1 hydrochloride can induce degradation of FKBP12 ^F36V-Nluc in vivo. (Pink: Target Protein Ligand (HY-114420); Black: Linker (HY-W012001); Blue: VHL Ligand (HY-112078); VHL Ligan+Linker (HY-173628A)) .

HY-101374A

AGN 192403 hydrochloride (+)-BRD4780	Imidazoline Receptor Caspase Mitochondrial Metabolism Lactate Dehydrogenase	Cardiovascular Disease Neurological Disease Cancer
AGN 192403 (BRD4780) hydrochloride is a potent and selective imidazoline-1 receptor antagonist with a K_i value of 42 nM. AGN 192403 hydrochloride is also a TMED9 inhibitor. AGN 192403 hydrochloride shows protective effects on oxidative cytotoxicity and mitochondrial inhibitor-induced cytotoxicity in astrocytes. AGN 192403 hydrochloride mitigates the proliferation and migration of differentiated glioma tumor cells. AGN 192403 hydrochloride can be used for glioma tumor and neurological diseases research .

HY-107922

Ethopropazine hydrochloride 1 Publications Verification Isothazine	Cholinesterase (ChE) iGluR mAChR	Neurological Disease
Ethopropazine (Isothazine) hydrochloride is a potent and selective BChE inhibitor, a poor AChE inhibitor and a non-selective mAChR and NMDA antagonist. Ethopropazine hydrochloride has anticholinergic, antihistamine, antiadrenergic actions and properties. Ethopropazine hydrochloride alleviates thermal hyperalgesia in a dose dependent manner. Ethopropazine hydrochloride can be used for the research of Parkinson’s disease .

HY-W012997

Tetrahydro-2H-pyran-2-one δ-valerolactone	Endogenous Metabolite	Others
Tetrahydro-2H-pyran-2-one (δ-valerolactone) is an endogenous metabolite with antioxidant capacity. Tetrahydro-2H-pyran-2-one is the small active molecule and can be used as drug intermediate .

HY-B0194A

Tizanidine hydrochloride	Adrenergic Receptor Apoptosis Akt Wnt β-catenin	Neurological Disease Endocrinology Cancer
Tizanidine hydrochloride, a skeletal muscle relaxant, is an orally effective central α₂-adrenoceptor agonist (IC₅₀ = 6.9 nmol). Tizanidine hydrochloride primarily exerts muscle relaxation effects by inhibiting the release of excitatory amino acids (glutamate and aspartate) from the presynaptic terminals of spinal cord interneurons. Tizanidine hydrochloride has anti-injury activity and can inhibit gastrointestinal (GI) transport. Tizanidine hydrochloride can inhibit the proliferation, migration, and invasion of lung cancer cells and induce cell apoptosis by upregulating Nischarin and inhibiting the AKT and Wnt3a/β-catenin signaling pathways. Tizanidine hydrochloride can be used to treat spasticity caused by diseases such as multiple sclerosis (MS), stroke, and spinal cord injury (SCI) .

HY-76487

Tetrahydro-4H-pyran-4-one	Biochemical Assay Reagents	Others
Dihydro-2H-pyran-4(3H)-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W010320

Ethyl maltol 2-Ethyl-3-hydroxy-4H-pyran-4-one	Environmental Pollutants Apoptosis Heme Oxygenase (HO)	Others
Ethyl maltol (2-Ethyl-3-hydroxy-4H-pyran-4-one) is an orally active and important food additive and flavor enhancer. Ethyl maltol is less toxic to rats and dogs. Ethyl maltol can enhance copper-mediated cytotoxicity and induce apoptosis in lung epithelial cells .

HY-W016349

Chelidamic acid	Amino Acid Decarboxylase	Others
Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid has good coordination ability with noble metal ions. Chelidamic acid is also one of the most potent inhibitors of glutamate decarboxylase, with a K_i of 33 μM.

HY-126534A

Abemaciclib metabolite M18 hydrochloride 2 Publications Verification LSN3106729 hydrochloride	Ligands for Target Protein for PROTAC CDK	Cancer
Abemaciclib metabolite M18 (LSN3106729) hydrochloride, the metabolite of Abemaciclib (HY-16297A), is a CDK inhibitor with antitumor activity. Abemaciclib metabolite M18 hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader .

HY-U00443

SB 258719	5-HT Receptor	Neurological Disease Cancer
SB 258719 is a selective 5-HT₇ receptor antagonist with high affinity (pK_i=7.5) for the receptor. SB 258719 can be used for the research of cancer and neurological disease .

HY-P2336A

CCZ01048 TFA 3 Publications Verification	Melanocortin Receptor	Cancer
CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a K_i of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .

HY-78694

*5-Bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methylbenzamide*	Drug Intermediate Histone Methyltransferase	Others
5-Bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methylbenzamide is a drug intermediate for synthesis of various active compounds.

HY-W044762

*5,6-Dihydro-2H-pyran-2-one*	Carbonic Anhydrase	Cancer
5,6-Dihydro-2H-pyran-2-one (Compound 1) is a prodrug-type carbonic anhydrase inhibitor. 5,6-Dihydro-2H-pyran-2-one can specifically inhibit the tumor-associated subtype hCA IX and the cytoplasmic subtype hCA I with K_i values of 1.35 and 8.03 μM. 5,6-Dihydro-2H-pyran-2-one can be used for the research on hypoxia-related cancer .

HY-34692

*3,4-Dihydro-2H-pyran-2-methanol*	Biochemical Assay Reagents	Others
(3,4-Dihydro-2H-pyran-2-yl)methanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W010469

*2,6-Dimethyl-4H-pyran-4-one* 2,6-Dimethyl-gamma-pyrone	Biochemical Assay Reagents	Others
2,6-Dimethyl-4H-pyran-4-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-47663

*5-((S)-2,2-Dimethyltetrahydro-2H-pyran-4-yl)-1-((1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl)-1H-indole-2-carboxylic acid*	Drug Intermediate	Others
5-((S)-2,2-Dimethyltetrahydro-2H-pyran-4-yl)-1-((1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl)-1H-indole-2-carboxylic acid (Compound 31k) is an intermediate of Orforglipron (HY-11218) .

HY-W003396

4-Bromotetrahydropyran	Biochemical Assay Reagents Drug Intermediate	Cancer
4-Bromotetrahydropyran (4-Bromotetrahydro-2H-pyran) is an intermediate. 4-Bromotetrahydropyran can be used in the synthesis of Example 32. 4-Bromotetrahydropyran can be used in triple-negative breast cancer research .

HY-119698

BAP9THP SD 8339; N-Benzyl-9-(tetrahydro-2h-pyran-2-yl)adenine	Environmental Pollutants Drug Derivative	Others
BAP9THP is a synthetic cytokinin derivative and a growth regulator. BAP9THP promotes chlorophyll retention (and senescence delay) in plant tissues exceptionally strongly, and growth of tobacco callus almost as strongly as 6-Benzylaminopurine (BAP). BAP9THP induces adventitious shoot formation ignificantly more strongly than N6-isopentenyladenine or Kinetin .

HY-103123

SB 258719 hydrochloride	5-HT Receptor	Neurological Disease Cancer
SB 258719 hydrochloride is a selective 5-HT₇ receptor antagonist displayed high affnity (pK_i=7.5) for the receptor. SB-258719 hydrochloride can be used for the research of cancer and neurological diseases .

HY-W012997S

Tetrahydro-2H-pyran-2-one-d4 δ-valerolactone-d₄	Isotope-Labeled Compounds Endogenous Metabolite	Others
Tetrahydro-2H-pyran-2-one-d₄ is the deuterium labeled Tetrahydro-2H-pyran-2-one. Tetrahydro-2H-pyran-2-one is an endogenous metabolite with antioxidant capacity. Tetrahydro-2H-pyran-2-one is the small active molecule and can be used as drug intermediate .

HY-W074305

*4H-Pyran-4-one* γ-Pyrone	Drug Derivative	Others
4H-pyran-4-one (γ-Pyrone) is a cyclic conjugated pyranone compound .

HY-79631

*(Tetrahydro-2H-pyran-4-yl)methanol*	HBV HCV	Others
(Tetrahydro-2H-pyran-4-yl)methanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W128289

2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran	PROTAC Linkers	Cancer
2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W072598

*N-(tert-Butoxycarbonyl)-O-(tetrahydro-2H-pyran-2-yl)-L-serine*	Amino Acid Derivatives	Others
N-(tert-Butoxycarbonyl)-O-(tetrahydro-2H-pyran-2-yl)-L-serine is a serine derivative .

HY-W045684

2-(Prop-2-yn-1-yloxy)tetrahydro-2H-pyran	PROTAC Linkers	Cancer
2-(Prop-2-yn-1-yloxy)tetrahydro-2H-pyran is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-N10208

Aspericin C	Endogenous Metabolite	Cancer
Aspericin C is a pyran derivative found in the marine-derived fungus Rhizopus sp. 2-PDA-61. Aspericin C shows cytotoxic activities against P388, A549, HL-60, and BEL-7420 cell lines (IC₅₀=14.6, 7.1, 61.4, and 24.2 μM, respectively) .

HY-32289

*tert-Butyl ((S)-1-amino-3-((R)-tetrahydro-2H-pyran-3-yl)propan-2-yl)(methyl)carbamate*	Drug Intermediate	Others
tert-Butyl ((S)-1-amino-3-((R)-tetrahydro-2H-pyran-3-yl)propan-2-yl)(methyl)carbamate is a drug intermediate for synthesis of various active compounds.

HY-41513

*(3-Iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-4-yl)methanol* [3-Iodo-1-(tetrahydropyran-2-yl)-1H-pyrazol-4-yl]-methanol	Drug Intermediate	Others
(3-Iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-4-yl)methanol ([3-Iodo-1-(tetrahydropyran-2-yl)-1H-pyrazol-4-yl]-methanol) is a drug intermediate for synthesis of various active compounds.

HY-44323

*2,3,4,6-Tetra-O-acetyl-1-S-acetyl-1-thiohexopyranose* (2R,3R,4S,5R,6S)-2-(Acetoxymethyl)-6-(acetylthio)tetrahydro-2H-pyran-3,4,5-triyl triacetate	Drug Intermediate	Others
2,3,4,6-Tetra-O-acetyl-1-S-acetyl-1-thiohexopyranose ((2R,3R,4S,5R,6S)-2-(Acetoxymethyl)-6-(acetylthio)tetrahydro-2H-pyran-3,4,5-triyl triacetate) is a drug intermediate for synthesis of various active compounds.

HY-134455

4-Nitrophenyl β-D-fucopyranoside	Biochemical Assay Reagents	Others
4-Nitrophenyl β-D-fuco-pyran-oside is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-101100

Anpirtoline hydrochloride D-16949 hydrochloride	5-HT Receptor	Neurological Disease
Anpirtoline (D-16949) hydrochloride is a centrally acting 5-HT_1B receptor agonist, with K_is of 28 nM (5-HT_1B), 150 nM (5-HT_1A) and 1.49 μM (5-HT2). Anpirtoline hydrochloride has serotonergic, antinociceptive, antidepressant-like effects .

HY-19562A

PF-06260933 hydrochloride 4 Publications Verification	MAP4K	Inflammation/Immunology
PF-06260933 hydrochloride is the hydrochloride form of PF-06260933 (HY-19562). PF-06260933 hydrochloride is an orally active and highly selective inhibitor of MAP4K4 with IC₅₀s of 3.7 and 160 nM for kinase and cell, respectively .

HY-114549

(R)-SCH-23982 hydrochloride	Dopamine Receptor	Neurological Disease
(R)-SCH-23982 hydrochloride is the R-enantiomer of SCH-23982 hydrochloride. SCH-23982 hydrochloride is a selective dopamine D1 receptor antagonist. (R)-SCH-23982 hydrochloride is promising for research of central nervous system disorders such as schizophrenia, Parkinson’s disease .

HY-I0838R

Peracetyl Empagliflozin (Standard)	Reference Standards
(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate (Standard) is the analytical standard of (2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate. This product is intended for research and analytical applications.

HY-W004264S

Tetrahydro-2H-pyran-4-ol-d5	Isotope-Labeled Compounds	Others
Tetrahydro-2H-pyran-4-ol-d₅ is the deuterium labeled Tetrahydro-2H-pyran-4-ol .

HY-W128280

2-(6-Bromohexyloxy)tetrahydro-2H-pyran	PROTAC Linkers	Cancer
2-(6-Bromohexyloxy)tetrahydro-2H-pyran is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W008007

2-(3-Bromopropoxy)tetrahydro-2H-pyran	PROTAC Linkers	Cancer
2-(3-Bromopropoxy)tetrahydro-2H-pyran is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-20838B

*(S)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)ethanoic acid*	Amino Acid Derivatives	Others
(S)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)ethanoic acid is a Glycine (HY-Y0966) derivative .

HY-23071A

*(R)-Ethyl 5-(2,2-dimethyltetrahydro-2H-pyran-4-yl)-1H-indole-2-carboxylate*	Drug Intermediate	Others
(R)-Ethyl 5-(2,2-dimethyltetrahydro-2H-pyran-4-yl)-1H-indole-2-carboxylate is a drug intermediate for synthesis of various active compounds.

HY-138813

N-Desethyl Sunitinib hydrochloride Maximum Cited Publications 6 Publications Verification SU-12662 hydrochloride	Drug Metabolite	Cancer
N-Desethyl Sunitinib (SU-12662) (hydrochloride) is a metabolite of sunitinib. Sunitinib is a potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor with K_i values of 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT, respectively .

HY-N1777

3,4-Dimethoxybenzamide	Drug Intermediate	Others
3,4-Dimethoxybenzamide, amide, is isolated from the solid culture of Streptoverticillium morookaense. 3,4-Dimethoxybenzamide can be used as the starting material to preparation Itopride hydrochloride .

HY-103376

NBI-27914 hydrochloride	CRFR	Neurological Disease
NBI-27914 (hydrochloride) is a selective Corticotropin-Releasing Factor 1 (CRF1) receptor antagonist with a K_i value of 1.7 nM .

HY-101820A

Simotinib hydrochloride	EGFR	Cancer
Simotinib hydrochloride is a selective, specific, and orally bioavailable EGFR tyrosine kinase inhibitor, with an IC₅₀ of 19.9 nM. Antineoplastic activities .

HY-116459

trans-Cevimeline hydrochloride AF102A hydrochloride	mAChR	Neurological Disease
Trans-Cevimeline (AF102A) (hydrochloride), as a trans-isomer of AF102B, is a M1 selective cholinergic agonist. Trans-Cevimeline (AF102A) (hydrochloride) can be used for the research of Alzheimer's disease .

HY-P11004

A3-APO	Bacterial Antibiotic	Infection
A3-APO is an antimicrobial peptide. A3-APO has a significant antimicrobial activity by a dual mode of action with both membrane disintegration and intracellular target inhibition. A3-APO can deactivate bacterial toxins and increase the expression of anti-inflammatory cytokines (such as IL-4 and IL-10), without antimicrobial resistance. A3-APO accelerates burn wounds healing in mice infection model of Acinetobacter baumannii and Staphylococcus aureus .

HY-121125

Aucubigenin	Others	Others
Aucubigenin, the aglycone of the iridoid glycoside aucubin, has been characterized through X-ray diffraction analysis. Its crystal structure reveals monoclinic symmetry with specific conformations adopted by its cyclopentane and pyran rings. The study also determined the absolute configurations of both aucubin and aucubigenin. Significant O-H O hydrogen bonding interactions were observed in the crystal lattices of both compounds, highlighting their structural stability and potential for intermolecular interactions .

HY-P10472

Azaline B	GnRH Receptor	Endocrinology
Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC₅₀ of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .

HY-P4757

N1-Glutathionyl-spermidine disulfide	Parasite	Others
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .

HY-W015863

4-Chlorotetrahydro-2H-pyran 4-Chlorotetrahydropyran	Biochemical Assay Reagents	Others
4-Chlorotetrahydro-2H-pyran (4-Chlorotetrahydropyran) is a starting material for organic synthesis .

HY-W012997R

Tetrahydro-2H-pyran-2-one (Standard) δ-valerolactone (Standard)	Reference Standards Endogenous Metabolite	Others
Tetrahydro-2H-pyran-2-one (δ-valerolactone) is an endogenous metabolite with antioxidant capacity. Tetrahydro-2H-pyran-2-one is the small active molecule and can be used as drug intermediate .

製品番号	製品名	Target	研究分野

HY-P2336A

CCZ01048 TFA 3 Publications Verification	Melanocortin Receptor	Cancer
CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a K_i of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .

HY-W072598

*N-(tert-Butoxycarbonyl)-O-(tetrahydro-2H-pyran-2-yl)-L-serine*	Amino Acid Derivatives	Others
N-(tert-Butoxycarbonyl)-O-(tetrahydro-2H-pyran-2-yl)-L-serine is a serine derivative .

HY-20838B

*(S)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)ethanoic acid*	Amino Acid Derivatives	Others
(S)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)ethanoic acid is a Glycine (HY-Y0966) derivative .

HY-P11004

A3-APO	Bacterial Antibiotic	Infection
A3-APO is an antimicrobial peptide. A3-APO has a significant antimicrobial activity by a dual mode of action with both membrane disintegration and intracellular target inhibition. A3-APO can deactivate bacterial toxins and increase the expression of anti-inflammatory cytokines (such as IL-4 and IL-10), without antimicrobial resistance. A3-APO accelerates burn wounds healing in mice infection model of Acinetobacter baumannii and Staphylococcus aureus .

HY-P10472

Azaline B	GnRH Receptor	Endocrinology
Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC₅₀ of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .

HY-P4757

N1-Glutathionyl-spermidine disulfide	Parasite	Others
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .

HY-20838A

*(R)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid*	Amino Acid Derivatives	Others
(R)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid is a Glycine (HY-Y0966) derivative .

HY-20841

Boc-(2S)-Gly-4-pyranoyl (S)-2-((tert-Butoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid; Boc-4-pyranoyl-Gly-OH	Amino Acid Derivatives	Others
Boc-(2S)-Gly-4-pyranoyl ((S)-2-((tert-Butoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid) is an amino-terminally protected glycine derivative that can be used to synthesize dipeptidyl peptidase IV with antidiabetic activity .

HY-P2075

EMD 55068	Renin	Endocrinology
EMD 55068 is a renin antagonist. EMD 55068 inhibits the uptake of taurocholate .

HY-P11692

Fmoc-Aeg-OtBu	Drug Intermediate	Others
Fmoc-Aeg-OtBu is an intermediate in solid-phase peptide synthesis, and serves as a building block for introducing pseudoproline motifs or backbone modifications .

製品番号	製品名	Category	Target	構造式

HY-W012997

Tetrahydro-2H-pyran-2-one δ-valerolactone	天然物 Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Tetrahydro-2H-pyran-2-one (δ-valerolactone) is an endogenous metabolite with antioxidant capacity. Tetrahydro-2H-pyran-2-one is the small active molecule and can be used as drug intermediate .

HY-N10208

Aspericin C	天然物 Microorganisms Classification of Application Fields Marine natural products Disease Research Fields Marine microorganism Cancer Source Classification	Endogenous Metabolite
Aspericin C is a pyran derivative found in the marine-derived fungus Rhizopus sp. 2-PDA-61. Aspericin C shows cytotoxic activities against P388, A549, HL-60, and BEL-7420 cell lines (IC₅₀=14.6, 7.1, 61.4, and 24.2 μM, respectively) .

HY-N1777

3,4-Dimethoxybenzamide	天然物 Microorganisms Classification of Application Fields Other Diseases Disease Research Fields Source Classification	Drug Intermediate
3,4-Dimethoxybenzamide, amide, is isolated from the solid culture of Streptoverticillium morookaense. 3,4-Dimethoxybenzamide can be used as the starting material to preparation Itopride hydrochloride .

HY-121125

Aucubigenin	Plantaginaceae Iridoids Terpenoids Plants Pseudolysimachion linariifolium subsp. dilatatum (Nakai & Kitag.) D. Y. Hong Source Classification	Others
Aucubigenin, the aglycone of the iridoid glycoside aucubin, has been characterized through X-ray diffraction analysis. Its crystal structure reveals monoclinic symmetry with specific conformations adopted by its cyclopentane and pyran rings. The study also determined the absolute configurations of both aucubin and aucubigenin. Significant O-H O hydrogen bonding interactions were observed in the crystal lattices of both compounds, highlighting their structural stability and potential for intermolecular interactions .

HY-W012997R

Tetrahydro-2H-pyran-2-one (Standard) δ-valerolactone (Standard)	Structural Classification 天然物 Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Tetrahydro-2H-pyran-2-one (δ-valerolactone) is an endogenous metabolite with antioxidant capacity. Tetrahydro-2H-pyran-2-one is the small active molecule and can be used as drug intermediate .

HY-N13197

*6-Methyl-5,6-dihydro-2H-pyran-2-one*	天然物 Microorganisms Source Classification	Antibiotic Bacterial Fungal Parasite
6-Methyl-5,6-dihydro-2H-pyran-2-one is a heterocyclic compound with antitumor, antifungal, antimicrobial, anti-inflammatory, antistress, antibiotic, antituberculosis, antiparasitic, antiviral activities .

HY-N10931

*4,5-Dihydroxy-2-((5-methyl-3,8-dimethylene-2-oxododecahydroazuleno[6,5-b]furan-5-yl)oxy)tetrahydro-2H-pyran-3-yl acetate*	Prosopis juliflora (Sw.) DC. Terpenoids Diterpenoids Plants Compositae Source Classification	Others
4,5-Dihydroxy-2-((5-methyl-3,8-dimethylene-2-oxododecahydroazuleno[6,5-b]furan-5-yl)oxy)tetrahydro-2H-pyran-3-yl acetate, a α-arabinopyranosides analogue, can be isolated from the aboveground part of barley .

HY-N9910

Visamminol	Ketones, Aldehydes, Acids Artemisia cana Pursh Umbelliferae Plants Source Classification	Endogenous Metabolite
Visamminol is a spasmolytic which can be extracted from Cimicifuga dahurica. Visamminol exhibits a spasmolytic action that is one-third as potent as that of papaverine hydrochloride .

HY-N14537

*5,6-Dihydro-4-methoxy-2H-pyran-2-one*	Microorganisms Antibiotics Other Antibiotics Source Classification	Others
5,6-Dihydro-4-methoxy-2H-pyran-2-one is found in the strain of Penicillum italicum MRC 1360 .

HY-N9098

*2-(4-Hydroxyphenyl)-6-methyl-2,3-dihydro-4H-pyran-4-one*	Monophenols Labiatae Derris robusta Phenols Plants Source Classification	Others
2-(4-Hydroxyphenyl)-6-methyl-2,3-dihydro-4H-pyran-4-one is a Phenols product that can be isolated from the herbs of Scutellaria barbata .

HY-N16625

*(S)-2-(4-Hydroxyphenyl)-6-methyl-2,3-dihydro-4H-pyran-4-one*	Structural Classification Monophenols Labiatae Derris robusta Phenols Plants Source Classification	Others
(S)-2-(4-Hydroxyphenyl)-6-methyl-2,3-dihydro-4H-pyran-4-one is a type of phenolic compound belonging to the class of dihydropyranones, and it can be found in Scutellaria barbata.

HY-N17602

Caloxanthone C Blancoxanthone	Structural Classification Xanthones Phenols Calophyllum blancoi Planch. & Triana Plants Calophyllaceae Source Classification	Drug Derivative
Caloxanthone C (Blancoxanthone) is a pyranoxanthone that can be found in the Calophyllum soulattri .

HY-W450115

USF 2550A	Structural Classification 天然物 Microorganisms Source Classification	Reactive Oxygen Species (ROS)
USF 2550A is a class of fungus-derived 2-pyran compound with DPPH free radical scavenging activity. USF 2550A binds to DPPH free radicals in organic solvents to form adducts, thereby achieving free radical scavenging; in acetate buffer, the formed adducts undergo degradation, and the degradation products can continuously scavenge free radicals. USF 2550A can be used in antioxidant-related research .

HY-W100057

5-Methylfuran-2(5H)-one	Structural Classification 天然物 Rhizophora apiculata Blume Rhizophoraceae Plants Source Classification	Drug Derivative
5-Methylfuran-2(5H)-one is a furan and pyran derivative compound that can be isolated from Rhizophora apiculata .

HY-N1777R

3,4-Dimethoxybenzamide (Standard)	Structural Classification 天然物 Microorganisms Source Classification	Reference Standards Drug Intermediate
3,4-Dimethoxybenzamide (Standard) is the analytical standard of 3,4-Dimethoxybenzamide. This product is intended for research and analytical applications. 3,4-Dimethoxybenzamide, amide, is isolated from the solid culture of Streptoverticillium morookaense. 3,4-Dimethoxybenzamide can be used as the starting material to preparation Itopride hydrochloride[1][2].

製品番号	製品名	構造式

HY-W012997S

Tetrahydro-2H-pyran-2-one-d4
Tetrahydro-2H-pyran-2-one-d₄ is the deuterium labeled Tetrahydro-2H-pyran-2-one. Tetrahydro-2H-pyran-2-one is an endogenous metabolite with antioxidant capacity. Tetrahydro-2H-pyran-2-one is the small active molecule and can be used as drug intermediate .

HY-W004264S

Tetrahydro-2H-pyran-4-ol-d5
Tetrahydro-2H-pyran-4-ol-d₅ is the deuterium labeled Tetrahydro-2H-pyran-4-ol .

HY-W009815S2

*6-Heptyltetrahydro-2H-pyran-2-one-d7*
6-Heptyltetrahydro-2H-pyran-2-one-d₇ is deuterated labeled 6-Heptyltetrahydro-2H-pyran-2-one.

HY-W009815S

*6-Heptyltetrahydro-2H-pyran-2-one-d2*
6-Heptyltetrahydro-2H-pyran-2-one-d₂ is deuterated labeled 6-Heptyltetrahydro-2H-pyran-2-one.

HY-W009815S1

*6-Heptyltetrahydro-2H-pyran-2-one-d4*
6-Heptyltetrahydro-2H-pyran-2-one-d₄ is deuterated labeled 6-Heptyltetrahydro-2H-pyran-2-one.

HY-W010320S

Ethyl maltol-d5
Ethyl maltol-d₅ is the deuterium labeled Ethyl maltol. Ethyl maltol (2-Ethyl-3-hydroxy-4H-pyran-4-one) is an orally active and important food additive and flavor enhancer. Ethyl maltol is less toxic to rats and dogs. Ethyl maltol can enhance copper-mediated cytotoxicity and induce apoptosis in lung epithelial cells .

HY-165668S

Pitavastatin lactone-d4
Pitavastatin lactone-d₄ (6S-((E)-2-(2-Cyclopropyl-4-(4-fluorophenyl-2,3,5,6-d₄)quinolin-3-yl)vinyl)-4R-hydroxytetrahydro-2H-pyran-2-one) is deuterium labeled Pitavastatin lactone .

HY-W753480

Phenol rutinoside-d5
Phenol rutinoside-d₅ is the deuterium labeled (2S,3R,4R,5R,6R)-2-Methyl-6-(((2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-phenoxytetrahydro-2H-pyran-2-yl)methoxy)tetrahydro-2H-pyran-3,4,5-triol (HY-W725466).

HY-W725464

4-Methylsyringol Gentiobioside-d6
4-Methylsyringol Gentiobioside-d₆ is the deuterium labeled (2S,3R,4S,5S,6R)-2-(2,6-Dimethoxy-4-methylphenoxy)-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-3,4,5-triol (HY-W725468).

HY-W717913

Guaiacol-β-D-glucopyranoside-d3
Guaiacol-β-D-glucopyranoside-d₃ is the deuterium labeled (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(2-methoxyphenoxy)tetrahydro-2H-pyran-3,4,5-triol (HY-W717912).

HY-W742150

4-Dehydroxy-3-dehydro-pitavastatin lactone-d5
4-Dehydroxy-3-dehydro-pitavastatin lactone-d₅ is the deuterium labeled (S,E)-6-(2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-5,6-dihydro-2H-pyran-2-one (Pitavastatin Impurity） (HY-Z3610).

HY-41880S

Glutaric anhydride-d6
Glutaric anhydride-d₆ is the deuterium labeled Glutaric anhydride .

HY-W749528

3-Deoxyglucosone-13C6
3-Deoxyglucosone- ¹³C₆ is the ¹³C-labeled (5s,6r)-2,5-dihydroxy-6-(hydroxymethyl)dihydro-2h-pyran-3(4h)-one (HY-W759076).

HY-W769530

Diosmetin 3',7-diglucuronide-d3
Diosmetin 3',7-diglucuronide-d₃ is the deuterium labeled (2S,3S,4S,5R,6S)-6-((2-(3-(((2S,3R,4S,5S,6S)-6-carboxy-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)-4-methoxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid (HY-W401408).

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