Ethopropazine hydrochloride (Standard)
Ethopropazine (hydrochloride) (Standard) is the analytical standard of Ethopropazine (hydrochloride) (HY-107922). This product is intended for research and analytical applications. Ethopropazine (Isothazine) hydrochloride is a potent and selective BChE inhibitor, a poor AChE inhibitor and a non-selective mAChR and NMDA antagonist. Ethopropazine hydrochloride has anticholinergic, antihistamine, antiadrenergic actions and properties. Ethopropazine hydrochloride alleviates thermal hyperalgesia in a dose dependent manner. Ethopropazine hydrochloride can be used for the research of Parkinson’s disease.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 1094-08-2
- Formula: C19H25ClN2S
- Molecular Weight:348.93
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1094-08-2
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Molecular Weight 348.93
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Formula C19H25ClN2S
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SMILES
CCN(C(CN1C2=CC=CC=C2SC3=CC=CC=C13)C)CC.[H]Cl
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Synonyms
Isothazine (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Giladi N, et al. Toxicity of the specific antimuscarinic agent methoctramine and other non-specific anticholinergic drugs in human neuroblastoma cell lines in vitro. Toxicol In Vitro. 1993 Sep;7(5):595-603. [Content Brief]
[2]. Inazu M, et al. Functional expression of choline transporter-like protein 1 (CTL1) in small cell lung carcinoma cells: a target molecule for lung cancer therapy. Pharmacol Res. 2013 Oct;76:119-31. [Content Brief]
[3]. Jevtovic-Todorovic V, et al. Anti-parkinsonian agents procyclidine and ethopropazine alleviate thermal hyperalgesia in neuropathic rats. Neuropharmacology. 2003 May;44(6):739-48. [Content Brief]
[4]. Sinko G, et al. Mechanism of stereoselective interaction between butyrylcholinesterase and ethopropazine enantiomers. Biochimie. 2011 Oct;93(10):1797-807. [Content Brief]
[5]. V. Debbeti, et al. Transition Metal Complexes of Ethopropazine: Synthesis and Characterization
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)