1. PROTAC
  2. PROTAC Linkers
  3. 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran

2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran is a PROTAC linker that can be used in the synthesis of PROTACs.

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2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran

2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran Chemische Struktur

CAS. Nr. : 40365-61-5

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Beschreibung

2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran is a PROTAC linker that can be used in the synthesis of PROTACs.

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E208 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molekulargewicht

154.21

Formel

C9H14O2

CAS. Nr.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

C#CCCOC1OCCCC1

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Reinheit & Dokumentation

Purity: 99.42%

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2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran
Art. -Nr.:
HY-W128289
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