5,6-Dihydro-2H-pyran-2-one
Based on 1 Customer Validation
5,6-Dihydro-2H-pyran-2-one (Compound 1) is a prodrug-type carbonic anhydrase inhibitor. 5,6-Dihydro-2H-pyran-2-one can specifically inhibit the tumor-associated subtype hCA IX and the cytoplasmic subtype hCA I with Ki values of 1.35 and 8.03 μM. 5,6-Dihydro-2H-pyran-2-one can be used for the research on hypoxia-related cancer.
For research use only. We do not sell to patients.
- CAS No.: 3393-45-1
- Formula: C5H6O2
- Molecular Weight:98.10
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
hCA IX 1.35 μM (Ki) |
hCA I 8.03 μM (Ki) |
Chemical Information
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CAS No. 3393-45-1
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Appearance Liquid
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Molecular Weight 98.10
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Formula C5H6O2
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Color Colorless to light yellow
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SMILES
O=C1OCCC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
5,6-Dihydro-2H-pyran-2-one Related Classifications
HY-W044762 Related Classifications
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