1. GPCR/G Protein
    Neuronal Signaling
  2. mAChR
  3. trans-Cevimeline hydrochloride

trans-Cevimeline hydrochloride (Synonyms: AF102A hydrochloride)

Cat. No.: HY-116459
Handling Instructions

Trans-Cevimeline (AF102A) (hydrochloride), as a trans-isomer of AF102B, is a M1 selective cholinergic agonist. Trans-Cevimeline (AF102A) (hydrochloride) can be used for the research of Alzheimer's disease.

For research use only. We do not sell to patients.

trans-Cevimeline hydrochloride Chemical Structure

trans-Cevimeline hydrochloride Chemical Structure

CAS No. : 107220-29-1

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Description

Trans-Cevimeline (AF102A) (hydrochloride), as a trans-isomer of AF102B, is a M1 selective cholinergic agonist. Trans-Cevimeline (AF102A) (hydrochloride) can be used for the research of Alzheimer's disease[1].

IC50 & Target

M1[1]

In Vivo

AF102A (1 mg/kg; i.p.) reverses cognitive impairments in a step-through passive avoidance task[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Rats[1]
Dosage: 1 mg/kg
Administration: I.p.
Result: Reversed cognitive impairments in a step-through passive avoidance task.
Molecular Weight

235.77

Formula

C₁₀H₁₈ClNOS

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
trans-Cevimeline hydrochloride
Cat. No.:
HY-116459
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