Search Result

Results for "

cationic+lipid

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (1) Biochemical Assay Reagents (8) CFTR (1) Drug Derivative (1) Endogenous Metabolite (1) Fluorescent Dye (1) IFNAR (2) Interleukin Related (2) Isotope-Labeled Compounds (6) Lipase (1) Liposome (127) mRNA (1) NF-κB (1)
By Research Areas:	Cancer (36) Infection (9) Inflammation/Immunology (24) Metabolic Disease (6) Neurological Disease (2)
Oligonucleotides:	Pegylated Lipids (1) Phospholipids (1) Cationic Lipids (101) Cholesterol (7)

135

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

MCE Kits

Natural
Products

Isotope-Labeled Compounds

109

Oligonucleotides

GMP Molecules

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-112251

D-Lin-MC3-DMA Maximum Cited Publications 147 Publications Verification	Liposome	Cancer
D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.

HY-134541

SM-102 40+ Cited Publications	Liposome	Infection
SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

HY-112754A

DOTAP chloride 10+ Cited Publications 1,2-Dioleoyl-3-trimethylammonium-propane chloride	Liposome	Cancer
DOTAP chloride is a useful and effective *cationic lipid* for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid .

HY-46760

LP01 2 Publications Verification	Liposome	Others
LP01 (Example 13) is a cationic lipid used in the delivery of biologically active agents to cells and tissues .

HY-130751

DODAP 1 Publications Verification	Liposome	Inflammation/Immunology
DODAP is a cationic lipid utilized as the lipid component in liposomes (pKa = 5.59 in TNS binding tests). DODAP is employed for encapsulating siRNA and delivering immunostimulated chemotherapeutic agents both in vitro and in vivo. DODAP holds great promise for research in vaccines and inflammation .

HY-170333

Lipid A-11 CICL1	Liposome	Inflammation/Immunology
Lipid A-11 (Compound A-11) (CICL1) is an ionizable cationic lipid. Lipid A-11 can be used to prepare lipid nanoparticles. Lipid A-11 can be used in research involving T cell-targeted transfection .

HY-152229

G0-C14 2 Publications Verification	Liposome	Cancer
G0-C14 is a cationic lipid-like compound alkyl-modified polyamidoamine (PAMAM) dendrimer. G0-C14 involves in the preparation of a series of macrophage-targeted nanoparticles (NPs). NPs can be used for agent and vaccine delivery .

HY-112755

DODMA	Liposome	Others
DODMA is a cationic lipid that can be used to prepare lipid nanoparticles. DODMA can be used for drug delivery .

HY-112757

DLinDMA 3 Publications Verification	Liposome	Others
DLinDMA, a ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. DLinDMA is used for siRNA delivery .

HY-W590532

306-O12B 1 Publications Verification	Liposome	Others
306-O12B is an ionizable cationic lipid used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA .

HY-139305

CL4H6 1 Publications Verification	Liposome	Cancer
CL4H6 is a pH-sensitive cationic lipid. CL4H6 is the main component of lipid nanoparticles (LNPs), which can be used to target and deliver siRNA, and induces a potent gene-silencing response .

HY-145225

DLin-K-C3-DMA	Liposome	Others
DLin-K-C3-DMA, a cationic lipid, can be used in the synthesis of nucleic acid-lipid particle to delivery of nucleic acid .

HY-159726

C10-200	Liposome	Others
C10-200 is an ionizable cationic lipid that can be used to generate lipid nanoparticles (LNPs). C10-200 is used in the study of mRNA delivery .

HY-142997

DOSPA	Liposome	Cancer
DOSPA is a cationic lipid. DOSPA can form lipid nanoparticles with DOPE (HY-112005) to serve as a carrier for nucleic acid transfection. DOSPA is applicable in research related to drug delivery .

HY-144014

MVL5	Liposome	Cancer
MVL5 is a non-degradable multivalent cationic lipid. MVL5 is a highly efficient vector for both DNA and siRNA. MVL5 can be used in breast cancer research .

HY-112523A

DMTAP	Liposome	Others
DMTAP is a cationic lipid that can be used for delivery of DNA, RNAi and drugs .

HY-144022

16:0 DAP	Liposome	Others
16:0 DAP is a cationic lipids that can be used for drug delivery, gene transfection and vaccine delivery .

HY-160553

9322-O16B	Liposome	Others
9322-O16B, an ionizable cationic lipid, is used for LNP generation .

HY-143210

Transfectam	Liposome	Metabolic Disease
Transfectam is a cationic lipid able to interact with DNA to form complexes that mediate efficient gene transfer into various eukaryotic cells .

HY-W590531

80-O16B	Biochemical Assay Reagents Liposome	Others
80-O16B is an ionizable cationic lipid containing disulfide bonds that can be used to prepare lipid nanoparticles (LNP) .

HY-153852

*LNP Lipid-7*	Liposome	Others
LNP Lipid-7 is a cationic lipid. LNP Lipid-7 can be used to prepare lipid nanoparticles (LNPs) for the delivery of drugs such as nucleic acids .

HY-149037A

GL67 pentahydrochloride N4-Spermine cholesteryl carbamate pentahydrochloride	Liposome	Others
GL67 (N4-Spermine cholesteryl carbamate) (pentahydrochloride) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .

HY-154804

DLin-M-C4-DMA	Liposome	Others
DLin-M-C4-DMA (Compound MC4) is a cationic lipid. DLin-M-C4-DMA can be used for delivery of nucleic acids .

HY-156857

PPZ-A10	Liposome	Inflammation/Immunology Cancer
PPZ-A10 is an ionizable cationic lipid. PPZ-A10 preferentially delivers mRNA to liver and spleen immune cells. Pi-LNPs containing PPZ-A10 can effectively deliver mRNA/siRNA to solid tumors .

HY-144025

DOBAQ	Liposome	Others
DOBAQ, a cationic lipid, is a pH-sensitive lipid. DOBAQ can be used for liposomes applied in drug delivery .

HY-159854

C14-O2	Liposome	Cancer
C14-O2 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .

HY-112763

CLinDMA	Liposome	Inflammation/Immunology
CLinDMA, a cationic lipid, can cause inflammatory response. CLinDMA can be used for the synthesis LNP201. LNP201 is a liposome assembly for systemic delivery of siRNA .

HY-157252

CL4F8-6	Liposome	Cancer
CL4F8-6 is an ionizable cationic lipid with a pK_a of 6.14. CL4F8-6 can be used in lipid nanoparticles (LNPs)-based mRNA therapeutics .

HY-160852

YSK 12C4	Liposome	Inflammation/Immunology
YSK 12C4 is an ionizable cationic lipid primarily used to enhance siRNA cellular delivery via multifunctional envelope-type nanodevices (MEND). YSK 12C4 promotes siRNA uptake and endosomal escape, effectively silencing genes in human immune cell lines .

HY-151511

A12-Iso5-2DC18	Liposome	Cancer
A12-Iso5-2DC18, an ionizable cationic lipid, is a potent mRNA delivery lipid vehicle .

HY-156936

RCB-02-4-8	Liposome	Others
RCB-02-4-8 is an ionizable cationic lipid that is used to form lipid nanoparticles (LNPs) to deliver mRNA. RCB-02-4-8 can improve the efficiency of lung transfection in mice .

HY-144016

16:0 EPC chloride	Liposome	Others
16:0 EPC chloride, a P-O-ethyl derivative, is a saturated cationic lipid. 16:0 EPC chloride can serve as a DNA and RNA transfecting agent. 16:0 EPC chloride can be used as a co-adjuvant for preparing vaccines and promote drug delivery .

HY-112251S

D-Lin-MC3-DMA-13C3	Isotope-Labeled Compounds	Others
D-Lin-MC3-DMA- ¹³C₃ is the ¹³C labeled D-Lin-MC3-DMA. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle .

HY-142999

DOIC	Liposome	Inflammation/Immunology
DOIC is a cationic lipid that can be used for RNA vaccines .

HY-W800783

DSTAP chloride CDESA	Liposome	Others
DSTAP chloride (CDESA) is a cationic lipid that used in the formation of lipid nanoparticles (LNPs). DORI chloride has high transfection efficiency .

HY-143688

EDMPC	Liposome	Others
EDMPC, a cationic lipid, has an enhanced ability to deliver DNA to pulmonary tissues. EDMPC mediates intralobar DNA delivery to rodents .

HY-156985

Lipid AX4	Isotope-Labeled Compounds Liposome	Others
Lipid AX4 is an ionizable cationic lipid with the _pK_a of 6.89， and can be used the study for the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo .

HY-149037

GL67 N4-Spermine cholesteryl carbamate	Liposome	Others
GL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .

HY-156448

80-O14B 1 Publications Verification	Liposome	Cancer
80-O14B is a cationic lipid-like compound. 80-O14B can be used in mRNA delivery studies .

HY-159859

IZ-Chol	Liposome	Others
IZ-Chol (IZ-Cholesterol) is an ionizable cationic lipid containing cholesterol. IZ-Chol-LNPs is highly potential to effectively complex with DNA, and endosome escape mechanisms mediated by proton sponge effect .

HY-W409806

Cholesterylamine	Liposome	Inflammation/Immunology
Cholesterylamine is a cationic lipid. Cholesterylamine can be added to the PLGA to prepare PLGA particle having surface charge. Cholesterylamine can be used for drug delivery. Cholesterylamine can be used for autoimmune diseases and allergy research .

HY-153737

113-N16B	Liposome	Others
113-N16B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs). 113-N16B delivers mRNA preferentially to pulmonary endothelial cells.

HY-W414069

Thiocholesterol	Endogenous Metabolite Liposome	Others
Thiocholesterol is a member of the class of cholesteric liquid crystals (CLCs) that can be used to synthesis cationic lipid. Thiocholesterol is a stronger stabilizer of silver nanoparticles (SNPs). Thiocholesterol can be used for plasma membrane research and drug delivery .

HY-151512

A12-Iso5-4DC19	Liposome	Inflammation/Immunology Cancer
A12-Iso5-4DC19 is an ionizable cationic lipid. A12-Iso5-4DC19 can facilitate mRNA delivery and be used for the research of RNA vaccines .

HY-142996

BGTC	Liposome	Cancer
BGTC is a non-amino acid cationic lipid. BGTC can be used for delivery of nucleic acids .

HY-144021

14:0 EPC chloride	Liposome	Others
14:0 EPC chloride is an acyl cationic lipid that can be used for liposomes applied in drug delivery .

HY-134780

L-369	Liposome	Others
L-369 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles and deliver mRNA .

HY-W800782

DC-6-14	Liposome	Others
DC-6-14 is a cationic lipid with gene transfection activity, which can be used for the synthesis of liposomes .

HY-W800776

DORI 1,2-Dioleoyl-3-dimethyl-hydroxyethylammonium bromide	Liposome	Others
DORI is a cationic lipid that can deliver plasmid DNA in vitro. DORI has lower cytotoxicity and high transfection efficiency .

HY-159862

IM21.7c	Liposome	Infection
IM21.7c is a cationic lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .

Cat. No.	Product Name

HY-L251

Ionizable Lipid Compound Library

95 compounds

Ionizable lipids are a class of specialized, functional lipid molecules with pH-sensitive charge characteristics. They are primarily divided into two major categories: ionizable cationic lipids and ionizable anionic lipids, though the term typically specifies ionizable cationic lipids within the biomedical field. Structurally, these lipids consist of an ionizable hydrophilic headgroup, a biodegradable linker, and hydrophobic tails. Their primary application is serving as the key delivery vehicle in lipid nanoparticles (LNPs) to encapsulate negatively charged nucleic acid macromolecules, such as mRNA vaccines, siRNA therapeutics, and CRISPR gene-editing components. In a physiological, neutral environment, they remain electrically neutral to minimize systemic toxicity and prolong circulation time. Upon entering the acidic microenvironment of cellular endosomes, however, they undergo protonation to become positively charged, thereby inducing membrane fusion and enabling the highly efficient intracellular release of the nucleic acid cargo. Consequently, they serve as the technological cornerstone for bringing nucleic acid therapies into clinical application.

To accelerate the translational process of cutting-edge nucleic acid drugs, MCE has meticulously constructed an ionizable lipid compound library containing 95 high-performance molecules, aiming to provide researchers and pharmaceutical professionals with a high-throughput, multi-dimensional lipid screening platform.

Cat. No.	Product Name	Type

HY-112754AGL

DOTAP chloride (GMP Like)

1,2-Dioleoyl-3-trimethylammonium-propane chloride (GMP Like)

Fluorescent Dyes

DOTAP chloride (GMP Like) is the GMP Like class DOTAP chloride (HY-112754A). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOTAP chloride is a cationic lipid with good membrane fusion ability and biocompatibility. DOTAP chloride (GMP Like) can be used as an excipient for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) without the use of helper lipid .

HY-134541GL

SM-102 (GMP Like)

Fluorescent Dyes

SM-102 (GMP Like) is SM-102 (HY-134541) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

HY-134541G

SM-102

Fluorescent Dyes

SM-102 (GMP) is SM-102 (HY-134541) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

HY-112251GL

D-Lin-MC3-DMA (GMP Like)	Fluorescent Dyes
D-Lin-MC3-DMA (GMP Like) is the GMP Like class D-Lin-MC3-DMA (HY-112251). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.

Cat. No.	Product Name	Type

HY-112251

D-Lin-MC3-DMA Maximum Cited Publications 147 Publications Verification	Biochemical Assay Reagents
D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.

HY-134541

SM-102 40+ Cited Publications	Biochemical Assay Reagents
SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

HY-112754A

DOTAP chloride 10+ Cited Publications 1,2-Dioleoyl-3-trimethylammonium-propane chloride	Biochemical Assay Reagents
DOTAP chloride is a useful and effective *cationic lipid* for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid .

HY-145405

C12-200 15+ Cited Publications	Biochemical Assay Reagents
C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .

HY-W127378

DOTAP methylsulfate

10+ Cited Publications

1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate

Biochemical Assay Reagents

DOTAP methylsulfat is a cationic lipid reagent, a cationic derivative of trimethylammonium, linked to two 18-carbon fatty acid tails, each with a single olefin group. DOTAP methylsulfat can self-assemble with negatively charged ions (such as DNA) to form complexes, which can be adsorbed to the cell membrane surface and enter the cell by electrostatic interaction and endocytosis, respectively. DOTAP methylsulfat promotes endosomal membrane fusion with its own hydrophobic domain, releases DNA into the cytoplasm, and exerts gene delivery function. DOTAP methylsulfat can be widely used in research fields such as gene therapy, cell transfection, and non-viral vector design .

HY-46760

LP01 2 Publications Verification	Biochemical Assay Reagents
LP01 (Example 13) is a cationic lipid used in the delivery of biologically active agents to cells and tissues .

HY-130751

DODAP 1 Publications Verification	Biochemical Assay Reagents
DODAP is a cationic lipid utilized as the lipid component in liposomes (pKa = 5.59 in TNS binding tests). DODAP is employed for encapsulating siRNA and delivering immunostimulated chemotherapeutic agents both in vitro and in vivo. DODAP holds great promise for research in vaccines and inflammation .

HY-139200

DOTMA

1 Publications Verification

Biochemical Assay Reagents

DOTMA is a cationic lipid that has been used as a non-viral vector for gene therapy. DOTMA is used as a component of liposomes to encapsulate siRNA, microRNA, and oligonucleotides and for in vitro gene transfection. DOTMA promotes effective interaction between liposomes and cell membranes by inducing positive charge on the liposomes. DOTMA showed good gene transfection effect both in vitro and in vivo .

HY-131119

Dimethyldioctadecylammonium bromide

Dioctadecyldimethylammonium bromide; DODAB

Biochemical Assay Reagents

Dimethyldioctadecylammonium bromide is a synthetic cationic lipid commonly used in gene delivery and vaccine development. Also known as DODAB or DDAB, it consists of a positively charged ammonium head group and two long hydrophobic tails. These properties make it useful for forming liposomes and other lipid-based nanoparticles that can efficiently deliver genetic material into cells. In addition to its applications in biotechnology, DDAB is also used in surfactants, emulsifiers and fabric softeners. However, due to its potential toxicity and irritation, extreme care should be taken when handling DDAB.

HY-152229

G0-C14 2 Publications Verification	Biochemical Assay Reagents
G0-C14 is a cationic lipid-like compound alkyl-modified polyamidoamine (PAMAM) dendrimer. G0-C14 involves in the preparation of a series of macrophage-targeted nanoparticles (NPs). NPs can be used for agent and vaccine delivery .

HY-112758

DLin-KC2-DMA 5+ Cited Publications	Biochemical Assay Reagents
DLin-KC2-DMA is an ionisable cationic lipid (pKa≈6) that is virtually non-toxic to antigen presenting cells (APCs). DLin-KC2-DMA produces significant siRNA-mediated gene silencing of GAPDH, when binds to lipid nanoparticles (LNP). DLin-KC2-DMA can be used in siRNA delivery studies .

HY-137131

DC-Chol hydrochloride

DC-Cholesterol hydrochloride

Biochemical Assay Reagents

DC-Chol hydrochloride is a cationic lipid. DC-Chol hydrochloride could inhibit Aβ40 fibril formation under appropriate experimental conditions. DC-Chol hydrochloride strongly inhibits amyloidogenesis of oxidized hCT in a dose-dependent manner. DC-Chol hydrochloride induces the production of Th1 (IL-2 and IFN-γ) and Th2 (IL-5) cytokines. DC-Chol hydrochloride can enhance the body's immune response to antigens. DC-Chol hydrochloride is used as a gene delivery vector. DC-Chol hydrochloride can be used in research in areas such as hepatitis B vaccines to improve vaccine immunity .

HY-112755

DODMA	Biochemical Assay Reagents
DODMA is a cationic lipid that can be used to prepare lipid nanoparticles. DODMA can be used for drug delivery .

HY-112757

DLinDMA 3 Publications Verification	Biochemical Assay Reagents
DLinDMA, a ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. DLinDMA is used for siRNA delivery .

HY-W590532

306-O12B 1 Publications Verification	Biochemical Assay Reagents
306-O12B is an ionizable cationic lipid used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA .

HY-143702

Fluorescent DOTAP

NBD-DOTAP

Biochemical Assay Reagents

Fluorescent DOTAP (NBD-DOTAP) is a cationic lipid which can be used for nucleic acid and protein delivery. Fluorescent DOTAP is labeled with a fluorophore NBD (maximum excitation/emission wavelength ∼463/536 nm). Fluorescent DOTAP can be used for gene delivery systems, drug delivery, as well as cell imaging and nanocarrier tracking. Fluorescent DOTAP is an ideal candidate for both biological and pharmaceutical formulation (e.g. co-delivery of vaccines) research .

HY-145225

DLin-K-C3-DMA	Biochemical Assay Reagents
DLin-K-C3-DMA, a cationic lipid, can be used in the synthesis of nucleic acid-lipid particle to delivery of nucleic acid .

HY-142997

DOSPA	Biochemical Assay Reagents
DOSPA is a cationic lipid. DOSPA can form lipid nanoparticles with DOPE (HY-112005) to serve as a carrier for nucleic acid transfection. DOSPA is applicable in research related to drug delivery .

HY-144014

MVL5	Biochemical Assay Reagents
MVL5 is a non-degradable multivalent cationic lipid. MVL5 is a highly efficient vector for both DNA and siRNA. MVL5 can be used in breast cancer research .

HY-147087

YSK 05	Biochemical Assay Reagents
YSK 05 is a pH-sensitive cationic lipid. YSK 05 improves the intracellular trafficking of non-viral vectors. YSK 05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK 05 overcomes the suppression of endosomal escape by PEGylation. YSK 05 effectively enhances siRNA delivery both in vitro and in vivo .

HY-112754AGL

DOTAP chloride (GMP Like)

1,2-Dioleoyl-3-trimethylammonium-propane chloride (GMP Like)

Biochemical Assay Reagents

HY-134541GL

SM-102 (GMP Like)

Biochemical Assay Reagents

HY-112523A

DMTAP	Biochemical Assay Reagents
DMTAP is a cationic lipid that can be used for delivery of DNA, RNAi and drugs .

HY-144022

16:0 DAP	Biochemical Assay Reagents
16:0 DAP is a cationic lipids that can be used for drug delivery, gene transfection and vaccine delivery .

HY-143210

Transfectam	Biochemical Assay Reagents
Transfectam is a cationic lipid able to interact with DNA to form complexes that mediate efficient gene transfer into various eukaryotic cells .

HY-153852

*LNP Lipid-7*	Biochemical Assay Reagents
LNP Lipid-7 is a cationic lipid. LNP Lipid-7 can be used to prepare lipid nanoparticles (LNPs) for the delivery of drugs such as nucleic acids .

HY-149037A

GL67 pentahydrochloride N4-Spermine cholesteryl carbamate pentahydrochloride	Biochemical Assay Reagents
GL67 (N4-Spermine cholesteryl carbamate) (pentahydrochloride) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .

HY-154804

DLin-M-C4-DMA	Biochemical Assay Reagents
DLin-M-C4-DMA (Compound MC4) is a cationic lipid. DLin-M-C4-DMA can be used for delivery of nucleic acids .

HY-156857

PPZ-A10	Biochemical Assay Reagents
PPZ-A10 is an ionizable cationic lipid. PPZ-A10 preferentially delivers mRNA to liver and spleen immune cells. Pi-LNPs containing PPZ-A10 can effectively deliver mRNA/siRNA to solid tumors .

HY-134541G

SM-102

Biochemical Assay Reagents

HY-144025

DOBAQ	Biochemical Assay Reagents
DOBAQ, a cationic lipid, is a pH-sensitive lipid. DOBAQ can be used for liposomes applied in drug delivery .

HY-112763

CLinDMA	Biochemical Assay Reagents
CLinDMA, a cationic lipid, can cause inflammatory response. CLinDMA can be used for the synthesis LNP201. LNP201 is a liposome assembly for systemic delivery of siRNA .

HY-157252

CL4F8-6	Biochemical Assay Reagents
CL4F8-6 is an ionizable cationic lipid with a pK_a of 6.14. CL4F8-6 can be used in lipid nanoparticles (LNPs)-based mRNA therapeutics .

HY-112251GL

D-Lin-MC3-DMA (GMP Like)	Biochemical Assay Reagents
D-Lin-MC3-DMA (GMP Like) is the GMP Like class D-Lin-MC3-DMA (HY-112251). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.

HY-151511

A12-Iso5-2DC18	Biochemical Assay Reagents
A12-Iso5-2DC18, an ionizable cationic lipid, is a potent mRNA delivery lipid vehicle .

HY-144016

16:0 EPC chloride	Biochemical Assay Reagents
16:0 EPC chloride, a P-O-ethyl derivative, is a saturated cationic lipid. 16:0 EPC chloride can serve as a DNA and RNA transfecting agent. 16:0 EPC chloride can be used as a co-adjuvant for preparing vaccines and promote drug delivery .

HY-142998

Vaxfectin

Biochemical Assay Reagents

Vaxfectin is a second-generation cationic lipid-based suspension that adjuvants effectively both pDNA and protein-based vaccines. Vaxfectin can boost the immune response against a range of pDNA-expressed pathogenic antigens in vivo. Vaxfectin can increase IgG titers and give rise to an IL-6 dependent enhancement of the humoral immune response without altering the Th1 type immune response. Vaxfectin can be studied for vaccine formulation .

HY-142999

DOIC	Biochemical Assay Reagents
DOIC is a cationic lipid that can be used for RNA vaccines .

HY-143688

EDMPC	Biochemical Assay Reagents
EDMPC, a cationic lipid, has an enhanced ability to deliver DNA to pulmonary tissues. EDMPC mediates intralobar DNA delivery to rodents .

HY-149037

GL67 N4-Spermine cholesteryl carbamate	Biochemical Assay Reagents
GL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .

HY-156448

80-O14B 1 Publications Verification	Biochemical Assay Reagents
80-O14B is a cationic lipid-like compound. 80-O14B can be used in mRNA delivery studies .

HY-153737

113-N16B	Biochemical Assay Reagents
113-N16B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs). 113-N16B delivers mRNA preferentially to pulmonary endothelial cells.

HY-W414069

Thiocholesterol	Biochemical Assay Reagents
Thiocholesterol is a member of the class of cholesteric liquid crystals (CLCs) that can be used to synthesis cationic lipid. Thiocholesterol is a stronger stabilizer of silver nanoparticles (SNPs). Thiocholesterol can be used for plasma membrane research and drug delivery .

HY-151512

A12-Iso5-4DC19	Biochemical Assay Reagents
A12-Iso5-4DC19 is an ionizable cationic lipid. A12-Iso5-4DC19 can facilitate mRNA delivery and be used for the research of RNA vaccines .

HY-142996

BGTC	Biochemical Assay Reagents
BGTC is a non-amino acid cationic lipid. BGTC can be used for delivery of nucleic acids .

HY-144021

14:0 EPC chloride	Biochemical Assay Reagents
14:0 EPC chloride is an acyl cationic lipid that can be used for liposomes applied in drug delivery .

HY-144020

14:0 DAP	Biochemical Assay Reagents
14:0 DAP (1,2-dimyristoyl-3-dimethylammonium-propane ) is a cationic lipid that can be used for drug delivery .

HY-156616

VC1052	Biochemical Assay Reagents
VC1052 is a dialkoxypropylammonium-based material and is the core cationic lipid component of the cationic lipid adjuvant Vaxfectin (HY-142998). Vaxfectin consists of VC1052 and lipid DPyPE (HY-112766) in a 1:1 molar ratio. Vaxfectin can be used as a vaccine adjuvant for the preparation of plasmid DNA and protein vaccines .

HY-144023

16:0-18:1 EPC chloride	Biochemical Assay Reagents
16:0-18:1 EPC chloride is a cationic lipid, which can be used for liposomes applied in drug delivery .

HY-133952

7-Oxotridecanedioic acid	Biochemical Assay Reagents
7-Oxotridecanedioic acid is a biodegradable cationic lipid intermediate compound for lipid nanoparticles formation. 7-Oxotridecanedioic acid can be incorporated into a lipid particle for delivering active agents .

Cat. No.	Product Name

HY-K2016

Protein Transfection Reagent 1 Publications Verification
MCE Protein Transfection Reagent is a cationic lipid mixture for complexation with proteins, peptides, antibodies and other biologically active molecules to allow their direct intracellular delivery.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W414069

Thiocholesterol	Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Steroids Source Classification	Endogenous Metabolite Liposome
Thiocholesterol is a member of the class of cholesteric liquid crystals (CLCs) that can be used to synthesis cationic lipid. Thiocholesterol is a stronger stabilizer of silver nanoparticles (SNPs). Thiocholesterol can be used for plasma membrane research and drug delivery .

HY-N15852

APL-719	Lipid	Biochemical Assay Reagents
APL-719 is a cationic lipid that can be used to synthesize lipid nanoparticles for drug delivery.

HY-N15802

APL-718 chloride	Lipid	Biochemical Assay Reagents
APL-718 chloride is a fixed cationic lipid.

HY-N16282

N-Tetamine-pLys40 TFA N,N-Ditetradecylamine-polylysine(40) TFA	Lipid	Biochemical Assay Reagents
N-Tetamine-pLys40 (N,N-Ditetradecylamine-polylysine(40)) TFA is a multivalent cationic lipid.

Cat. No.	Product Name	Chemical Structure

HY-134541S6

SM-102-d4
SM-102-d₄ is the deuterium labeled SM-102 (HY-134541). SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

HY-112251S

D-Lin-MC3-DMA-13C3
D-Lin-MC3-DMA- ¹³C₃ is the ¹³C labeled D-Lin-MC3-DMA. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle .

HY-112754AS

DOTAP-d9 chloride
DOTAP-d₉ chloride is the deuterium labeled DOTAP chloride (HY-112754A). DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid .

HY-112251S1

D-Lin-MC3-DMA-d6
D-Lin-MC3-DMA-d₆ is the deuterium labeled D-Lin-MC3-DMA (HY-112251). D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.

HY-W724291

Dimethyldioctadecylammonium-d3 bromide

Dimethyldioctadecylammonium-d₃ bromide (Dioctadecyldimethylammonium-d₃ bromide) is the deuterium labeled Dimethyldioctadecylammonium bromide (HY-131119). Dimethyldioctadecylammonium bromide is a synthetic cationic lipid commonly used in gene delivery and vaccine development. Also known as DODAB or DDAB, it consists of a positively charged ammonium head group and two long hydrophobic tails. These properties make it useful for forming liposomes and other lipid-based nanoparticles that can efficiently deliver genetic material into cells. In addition to its applications in biotechnology, DDAB is also used in surfactants, emulsifiers and fabric softeners. However, due to its potential toxicity and irritation, extreme care should be taken when handling DDAB.

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-112251GL

D-Lin-MC3-DMA (GMP Like)	Liposome	Cancer
D-Lin-MC3-DMA (GMP Like) is the GMP Like class D-Lin-MC3-DMA (HY-112251). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.

HY-112754AGL

DOTAP chloride (GMP Like) 1,2-Dioleoyl-3-trimethylammonium-propane chloride (GMP Like)	Liposome	Others
DOTAP chloride (GMP Like) is the GMP Like class DOTAP chloride (HY-112754A). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOTAP chloride is a cationic lipid with good membrane fusion ability and biocompatibility. DOTAP chloride (GMP Like) can be used as an excipient for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) without the use of helper lipid .

HY-134541G

SM-102	Liposome	Infection
SM-102 (GMP) is SM-102 (HY-134541) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

HY-134541GL

SM-102 (GMP Like)	Liposome	Infection
SM-102 (GMP Like) is SM-102 (HY-134541) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

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