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Referencia número: HY-168370

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YHS-12

Name: YHS-12
Brand: MedChemExpress
SKU: HY-168370
Price: 76.00 USD
Availability: InStock
Rating: 5 (1 reviews)

YHS-12 is an ionizable cationic lipid, which can be used to synthesize lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 2959463-68-2
Fòrmula: C₅₆H₁₁₂N₄O₂
Peso molecular:873.51

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

YHS-12 Chemical Structure

No. CAS: 2959463-68-2

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Top Publications Citing

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Actividad biológica

Descripciòn

YHS-12 is an ionizable cationic lipid, which can be used to synthesize lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA^[1].

Chemical Information

No. CAS 2959463-68-2
Peso molecular 873.51
Fòrmula C₅₆H₁₁₂N₄O₂
SMILES

CCCCCCCCCCCCN(CCCCCCCCCCCC)CCNC(/C=C/C(NCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Tang C, et al. mRNA-Laden Lipid-Nanoparticle-Enabled in Situ CAR-Macrophage Engineering for the Eradication of Multidrug-Resistant Bacteria in a Sepsis Mouse Model. ACS Nano. 2024 Jan 23;18(3):2261-2278. [Content Brief]

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Topics Lipid Nanoparticles: Key Nucleic Acid Delivery Vectors
Lipid nanoparticles (LNPs) are the most clinically advanced non-viral delivery systems for nucleic acid therapeutics and enable the in vivo delivery of mRNA, siRNA, and other genetic cargos.

2026-06-18

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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