80-O14B
Based on 1 publication(s) in Google Scholar
80-O14B is a cationic lipid-like compound. 80-O14B can be used in mRNA delivery studies.
For research use only. We do not sell to patients.
- Purity: 99.56%
- CAS No.: 1624618-01-4
- Formula: C35H70N2O4S4
- Molecular Weight:711.20
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
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Bioactive Compound Library
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Metabolism/Protease Compound Library
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Anti-Cancer Compound Library
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Lipid Compound Library
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MCE Bioactive Compound Library
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High-Throughput Bioactive Compound Library
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Liposome Library
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Ionizable Lipid Compound Library
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Publications Citing Use of MedChemExpress (MCE) 80-O14B
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Biological Activity
Chemical Information
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CAS No. 1624618-01-4
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Appearance Viscous Liquid
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Molecular Weight 711.20
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Formula C35H70N2O4S4
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Color Colorless to light yellow
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SMILES
O=C(CCN(CCCN(C)C)CCC(OCCSSCCCCCCCCCC)=O)OCCSSCCCCCCCCCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
Solvent & Solubility
DMSO : 100 mg/mL (140.61 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: 2.5 mg/mL (3.52 mM); Clear solution; Need ultrasonic
This protocol yields a clear solution of 2.5 mg/mL.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4061 mL | 7.0304 mL | 14.0607 mL | 35.1519 mL |
| 5 mM | 0.2812 mL | 1.4061 mL | 2.8121 mL | 7.0304 mL | |
| 10 mM | 0.1406 mL | 0.7030 mL | 1.4061 mL | 3.5152 mL | |
| 15 mM | 0.0937 mL | 0.4687 mL | 0.9374 mL | 2.3435 mL | |
| 20 mM | 0.0703 mL | 0.3515 mL | 0.7030 mL | 1.7576 mL | |
| 25 mM | 0.0562 mL | 0.2812 mL | 0.5624 mL | 1.4061 mL | |
| 30 mM | 0.0469 mL | 0.2343 mL | 0.4687 mL | 1.1717 mL | |
| 40 mM | 0.0352 mL | 0.1758 mL | 0.3515 mL | 0.8788 mL | |
| 50 mM | 0.0281 mL | 0.1406 mL | 0.2812 mL | 0.7030 mL | |
| 60 mM | 0.0234 mL | 0.1172 mL | 0.2343 mL | 0.5859 mL | |
| 80 mM | 0.0176 mL | 0.0879 mL | 0.1758 mL | 0.4394 mL | |
| 100 mM | 0.0141 mL | 0.0703 mL | 0.1406 mL | 0.3515 mL |
80-O14B Related Classifications
HY-156448 Related Classifications
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