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YSK 05 

Cat. No.: HY-147087
Handling Instructions

YSK 05 is a pH-sensitive cationic lipid. YSK 05 improves the intracellular trafficking of non-viral vectors. YSK 05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK 05 overcomes the suppression of endosomal escape by PEGylation. YSK 05 effectively enhances siRNA delivery both in vitro and in vivo.

For research use only. We do not sell to patients.

YSK 05 Chemical Structure

YSK 05 Chemical Structure

CAS No. : 1318793-78-0

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Description

YSK 05 is a pH-sensitive cationic lipid. YSK 05 improves the intracellular trafficking of non-viral vectors. YSK 05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK 05 overcomes the suppression of endosomal escape by PEGylation. YSK 05 effectively enhances siRNA delivery both in vitro and in vivo[1].

In Vitro

YSK 05 facilitates the endosomal escape of the MEND and thereby enhances the efficacy of siRNA delivery into cytosol and gene silencing[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

628.07

Formula

C42H77NO2

CAS No.
SMILES

CN1CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)(OCCCCCCCC/C=C\C/C=C\CCCCC)CC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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YSK 05
Cat. No.:
HY-147087
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