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United States

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Cat. No.: HY-172336

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4-O10b1

4-O10b1 is an ionizable cationic lipid. 4-O10b1 can be used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo.

For research use only. We do not sell to patients.

Formula: C₆₂H₁₂₀N₄O₈
Molecular Weight:1049.64

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

4-O10b1 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

4-O10b1 is an ionizable cationic lipid. 4-O10b1 can be used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo^[1].

Chemical Information

Molecular Weight 1049.64
Formula C₆₂H₁₂₀N₄O₈
SMILES

CC(OC(CCN(CCCN1CCN(CC1)CCCN(CCC(OC(CCCCCCCC)C)=O)CCC(OC(CCCCCCCC)C)=O)CCC(OC(CCCCCCCC)C)=O)=O)CCCCCCCC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhao G, et al. Precision treatment of viral pneumonia through macrophage-targeted lipid nanoparticle delivery. Proc Natl Acad Sci U S A. 2024 Feb 13;121(7):e2314747121. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Minimum order quantity

100 mg

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