Cholesterylamine
Based on 1 Customer Validation
Cholesterylamine is a cationic lipid and cholesterol analog. Cholesterylamine mimics the membrane transport properties of cholesterol, cycles between the plasma membrane and early/recycling endosomes in mammalian cells, and serves as a platform for constructing synthetic cell surface receptors. Cholesterylamine can be used to prepare PLGA particles with surface charges for antigen binding. Cholesterylamine is applicable for drug delivery. Cholesterylamine is used in research on autoimmune diseases and allergies.
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 2126-93-4
- Formula: C27H47N
- Molecular Weight:385.67
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MDCK-II | IC50 |
8.6 μM
Compound: 1f
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Antiviral activity against Influenza A/PR8/34 (H1N1) virus infected in MDCK2 cells assessed as inhibition of virus reproduction by ELISA
Antiviral activity against Influenza A/PR8/34 (H1N1) virus infected in MDCK2 cells assessed as inhibition of virus reproduction by ELISA
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[PMID: 23916260] |
In Vitro
Cholesterylamine can modify the surface of PLGA nanoparticles to enable efficient non-covalent adsorption of antigens such as Ovalbumins (HY-W250978), thus preparing antigen-coated nanoparticles for inducing immune tolerance[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2126-93-4
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Appearance Solid
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Molecular Weight 385.67
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Formula C27H47N
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Color White to yellow
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SMILES
N[C@H]1CC[C@]2(C)[C@@]3([H])CC[C@]4(C)[C@@H]([C@H](C)CCCC(C)C)CC[C@@]4([H])[C@]3([H])CC=C2C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
In Vitro:
Chloroform : ≥ 50 mg/mL (129.64 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (281 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Chloroform | 1 mM | 2.5929 mL | 12.9645 mL | 25.9289 mL | 64.8223 mL |
| 5 mM | 0.5186 mL | 2.5929 mL | 5.1858 mL | 12.9645 mL | |
| 10 mM | 0.2593 mL | 1.2964 mL | 2.5929 mL | 6.4822 mL | |
| 15 mM | 0.1729 mL | 0.8643 mL | 1.7286 mL | 4.3215 mL | |
| 20 mM | 0.1296 mL | 0.6482 mL | 1.2964 mL | 3.2411 mL | |
| 25 mM | 0.1037 mL | 0.5186 mL | 1.0372 mL | 2.5929 mL | |
| 30 mM | 0.0864 mL | 0.4321 mL | 0.8643 mL | 2.1607 mL | |
| 40 mM | 0.0648 mL | 0.3241 mL | 0.6482 mL | 1.6206 mL | |
| 50 mM | 0.0519 mL | 0.2593 mL | 0.5186 mL | 1.2964 mL | |
| 60 mM | 0.0432 mL | 0.2161 mL | 0.4321 mL | 1.0804 mL | |
| 80 mM | 0.0324 mL | 0.1621 mL | 0.3241 mL | 0.8103 mL | |
| 100 mM | 0.0259 mL | 0.1296 mL | 0.2593 mL | 0.6482 mL |
Cholesterylamine Related Classifications
HY-W409806 Related Classifications
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