2126-93-4
Chemical Structure
Cholesterylamine
- CAS No.: 2126-93-4
- Formula:C27H47N
- Molecular Weight:385.67
IUPAC Name: 4-(6-bromo-1H-indol-3-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine
InChIKey: YGPZWPHDULZYFR-DPAQBDIFSA-N
SMILES: N[C@H]1CC[C@]2(C)[C@@]3([H])CC[C@]4(C)[C@@H]([C@H](C)CCCC(C)C)CC[C@@]4([H])[C@]3([H])CC=C2C1
Biological Activity: Cholesterylamine is a cationic lipid and cholesterol analog. Cholesterylamine mimics the membrane transport properties of cholesterol, cycles between the plasma membrane and early/recycling endosomes in mammalian cells, and serves as a platform for constructing synthetic cell surface receptors. Cholesterylamine can be used to prepare PLGA particles with surface charges for antigen binding. Cholesterylamine is applicable for drug delivery. Cholesterylamine is used in research on autoimmune diseases and allergies[1][2].
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Cholesterylamine | 95.0% | Cholesterylamine is a cationic lipid and cholesterol analog. Cholesterylamine mimics the membrane transport properties of cholesterol, cycles between the plasma membrane and early/recycling endosomes in mammalian cells, and serves as a platform for constructing synthetic cell surface receptors. Cholesterylamine can be used to prepare PLGA particles with surface charges for antigen binding. Cholesterylamine is applicable for drug delivery. Cholesterylamine is used in research on autoimmune diseases and allergies. | ||||||||||||||||||||
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- [1]. Tianxin Wang, et al. Methods, compositions and therapeutical vaccine for autoimmune diseases and allergy treatment. US20220025015A1. 2022-01-27
- [2]. Hymel D, et al. Synthetic cell surface receptors for delivery of therapeutics and probes. Advanced drug delivery reviews. 2012 Jun 15;64(9):797-810.
Keywords
