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Cat. No.: HY-151511

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A12-Iso5-2DC18

Name: A12-Iso5-2DC18
Brand: MedChemExpress
SKU: HY-151511
Price: 528.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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A12-Iso5-2DC18, an ionizable cationic lipid, is a potent mRNA delivery lipid vehicle.

For research use only. We do not sell to patients.

Purity : 97.62%
CAS No.: 2412492-06-7
Formula: C₄₅H₈₅N₃O₂
Molecular Weight:700.18

Storage:

Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

A12-Iso5-2DC18 Chemical Structure

CAS No.: 2412492-06-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

A12-Iso5-2DC18, an ionizable cationic lipid, is a potent mRNA delivery lipid vehicle^[1].

Chemical Information

CAS No. 2412492-06-7
Appearance Liquid (Density: 0.924±0.14 g/cm³)
Molecular Weight 700.18
Formula C₄₅H₈₅N₃O₂
Color Colorless to light yellow
SMILES

CCCCCCCC/C=C\CCCCCCCC1(CCCCCCC/C=C\CCCCCCCC)C=NC(N1CCCN(C)C)C(OCC)=O
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Protocols

All Molecular Biology

RNA extraction experimental
By lysing cells, releasing RNA, and removing impurities such as proteins and DNA, high-purity RNA products are finally obtained. The commonly used traditional method is the guanidine isothiocyanate/phenol/chloroform method (Trizol), which is suitable for a variety of animal materials including animal tissues, microorganisms, cultured cells, etc., and most plant materials.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Miao L, et al. Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation. Nat Biotechnol. 2019 Oct;37(10):1174-1185. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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