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Results for "

macrolide+antibiotic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aminotransferases (Transaminases) (3) Antibiotic (124) Apoptosis (11) ATP Synthase (1) Autophagy (6) Bacterial (108) Calcium Channel (2) CDK (1) COX (3) Dengue Virus (3) DNA/RNA Synthesis (11) Drug Derivative (1) Drug Intermediate (2) Drug Metabolite (2) Endogenous Metabolite (3) Environmental Pollutants (2) Flavivirus (3) Fungal (13) GABA Receptor (1) Insecticide (1) Isotope-Labeled Compounds (8) Na+/K+ ATPase (1) NF-κB (3) NO Synthase (3) P-glycoprotein (2) p38 MAPK (1) Parasite (14) Proton Pump (4) Reference Standards (22)
By Research Areas:	Cancer (24) Cardiovascular Disease (1) Infection (130) Inflammation/Immunology (12) Neurological Disease (1)

By Targets:

Aminotransferases (Transaminases) (3)

Antibiotic (124)

Apoptosis (11)

ATP Synthase (1)

Autophagy (6)

Bacterial (108)

Calcium Channel (2)

CDK (1)

COX (3)

Dengue Virus (3)

DNA/RNA Synthesis (11)

Drug Derivative (1)

Drug Intermediate (2)

Drug Metabolite (2)

Endogenous Metabolite (3)

Environmental Pollutants (2)

Flavivirus (3)

Fungal (13)

GABA Receptor (1)

Insecticide (1)

Isotope-Labeled Compounds (8)

Na+/K+ ATPase (1)

NF-κB (3)

NO Synthase (3)

P-glycoprotein (2)

p38 MAPK (1)

Parasite (14)

Proton Pump (4)

Reference Standards (22)

By Research Areas:

Cancer (24)

Cardiovascular Disease (1)

Infection (130)

Inflammation/Immunology (12)

Neurological Disease (1)

140

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17506

Azithromycin 40+ Cited Publications CP 62993	Bacterial Autophagy Antibiotic Parasite	Infection Cancer
Azithromycin is a macrolide antibiotic useful for the treatment of a number of bacterial infections.

HY-N1724

Concanamycin A 25+ Cited Publications Antibiotic X 4357B; Folimycin; X 4357B	Proton Pump Bacterial Antibiotic	Infection Inflammation/Immunology Cancer
Concanamycin A (Folimycin; Antibiotic X 4357B) is a macrolide antibiotic, a vacuolar type H ⁺-ATPase (V-ATPase) inhibitor. Concanamycin A is also an inhibitor of lysosomal acidification, can be used to T cell-mediated inflammation research ^- .

HY-B0133

Natamycin 5+ Cited Publications Pimaricin	Environmental Pollutants Antibiotic Endogenous Metabolite Fungal Bacterial	Infection
Natamycin (Pimaricin) is a macrolide antibiotic agent produced by several Streptomyces strains. Natamycin inhibits the growth of fungi via inhibition of amino acid and glucose transport across the plasma membrane. Natamycin is a food preservative, an antifungal agent in agriculture, and is widely used for fungal keratitis research .

HY-15662

Tulathromycin A 2 Publications Verification Tulathromycin; CP 472295	Antibiotic Bacterial	Infection
Tulathromycin A (Tulathromycin), a macrolide antibiotic, inhibits protein synthesis (IC₅₀=0.26 µM) by targeting bacterial ribosome. Tulathromycin A is used for the research of respiratory disease in cattle and swine. Immunomodulatory effects .

HY-100593

Spiramycin 1 Publications Verification Rovamycin	Bacterial Parasite Antibiotic	Infection
Spiramycin (Rovamycin) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect. Spiramycin is composed of a 16-member lactone ring, on which three sugars (mycaminose, forosamine, and mycarose) are attached .

HY-B0519A

Tylosin 1 Publications Verification	Bacterial Antibiotic	Infection
Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-B1920

Josamycin 1 Publications Verification EN-141	Bacterial Antibiotic	Infection
Josamycin (EN-141) is an orally active macrolide antibiotic exhibiting antimicrobial activity against a wide spectrum of pathogens, such as bacteria. The dissociation constant K_d from ribosome for Josamycin is 5.5 nM .

HY-116010

Oleandomycin 1 Publications Verification	Bacterial Antibiotic	Infection
Oleandomycin is a macrolide antibiotic structurally closely related to Erythromycin. Oleandomycin is similar to Erythromycin with antimicrobial activity. Oleandomycin inhibits protein synthesis by interference with translation of activated amino acids to nascent peptide chains on the ribosomes .

HY-17506A

Azithromycin hydrate 40+ Cited Publications CP-62993 dihydrate	Bacterial Autophagy Antibiotic Parasite	Infection Cancer
Azithromycin hydrate is a macrolide antibiotic useful for the treatment of a number of bacterial infections.

HY-N7112

Leucomycin 1 Publications Verification Kitasamycin	Bacterial Antibiotic	Infection
Leucomycin (Kitasamycin) is an orally active macrolide antibiotic produced by Streptomyces kitasatoensis. Leucomycin has broad-spectrum antibacterial activities against gram-positive and gram-negative bacteria, mycoplasma, leptospira, spirochaetes, rickettsiae and some larger viruses .

HY-N7121

Erythromycin estolate 1 Publications Verification	Antibiotic Bacterial Aminotransferases (Transaminases) Flavivirus Dengue Virus	Infection
Erythromycin estolate is the Erythromycin (HY-B0220) derivative , is a macrolide antibiotic used in the treatment of a wide variety of bacterial infections. Erythromycin estolate causes several cases of liver injury which mostly include cholestatic hepatitis. Erythromycin estolate toxicity is related to its inhibitory effect on bile acid transport .

HY-128423

Tylvalosin tartrate 2 Publications Verification Acetylisovaleryltylosin tartrate	Antibiotic Bacterial NF-κB Apoptosis	Infection Inflammation/Immunology
Tylvalosin (Acetylisovaleryltylosin) tartrate is an orally active, broad-spectrum macrolide antibiotic with antimicrobial activity. Tylvalosin tartrate is an antiviral agent useful in studying PRRSV infection. Tylvalosin tartrate induces apoptosis. Tylvalosin tartrate also has anti-inflammatory activity, relieves oxidative stress, and alleviates acute lung injury by inhibiting NF-κB activation .

HY-B1908

Midecamycin 2 Publications Verification SF-837; Antibiotic SF-837	Bacterial Antibiotic	Infection
Midecamycin, an acetoxy-substituted macrolide antibiotic, is tested against gram-positive and gram-negative bacteria.

HY-128423A

Tylvalosin 2 Publications Verification Acetylisovaleryltylosin	Antibiotic Bacterial NF-κB Apoptosis	Infection Inflammation/Immunology Cancer
Tylvalosin (Acetylisovaleryltylo?sin) is an orally active, broad-spectrum macrolide antibiotic with antimicrobial activity. Tylvalosin is an antiviral agent used to study PRRSV infection. Tylvalosin induces apoptosis. Tylvalosin also has anti-inflammatory activity, alleviates oxidative stress, and alleviates acute lung injury by inhibiting NF-κB activation .

HY-B0519B

Tylosin phosphate 1 Publications Verification	Bacterial Antibiotic	Infection
Tylosin phosphate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin phosphate is widely used as a feed additive for promoting animal growth. Tylosin phosphate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-N7141

Spiramycin I 1 Publications Verification	Antibiotic Parasite Bacterial	Infection
Spiramycin I is a macrolide antibiotic and antiparasitic .

HY-106681

Lagosin Fungichromin; Pentamycin; Cogomycin	Antibiotic Fungal	Cancer
Lagosin (Fungichromin) is a polyene macrolide antibiotic. Lagosin has demonstrated broad-spectrum antifungal activity and is impervious to agent resistance .

HY-17506S

Azithromycin-d3	Bacterial Antibiotic Autophagy Isotope-Labeled Compounds	Infection Cancer
Azithromycin-d₃ is the deuterium labeled Azithromycin. Azithromycin (CP-62993) is a macrolide antibiotic useful for the treatment of a number of bacterial infections .

HY-B0643

Dirithromycin 1 Publications Verification LY237216	Bacterial Antibiotic	Infection
Dirithromycin (LY237216), a derivative of Erythromycin, is a potent and orally active semi-synthetic macrolide antibiotic. Dirithromycin is active against gram-positive bacteria, Legionella spp., Helicobacter pylori, and Chlamydia trachomatis .

HY-B0435S

Roxithromycin-d7 RU-28965-d₇	Isotope-Labeled Compounds Antibiotic Bacterial	Others
Roxithromycin-d₇ (RU-28965-d₇) is the deuterium labeled Roxithromycin (HY-B0435) . Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic .

HY-122207

Erythromycin A enol ether	Antibiotic	Infection
Erythromycin A enol ether is an acidic degradation product of Erythromycin A (macrolide antibiotic) and has no antibacterial effect .

HY-17506AR

Azithromycin hydrate (Standard) CP-62993 dihydrate (Standard)	Reference Standards Bacterial Autophagy Antibiotic Parasite	Infection Cancer
Azithromycin (hydrate) (Standard) is the analytical standard of Azithromycin (hydrate). This product is intended for research and analytical applications. Azithromycin hydrate is a macrolide antibiotic useful for the treatment of a number of bacterial infections.

HY-126906

Milbemycin A4	Environmental Pollutants Antibiotic P-glycoprotein	Cancer
Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity sup>[2].

HY-120809

Spiramycin III	Bacterial Parasite Antibiotic	Infection
Spiramycin III (SPMIII) is a main component of Spiramycin. Spiramycin (HY-100593) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect .

HY-N6783

Oligomycin C 1 Publications Verification	Fungal Antibiotic	Infection
Oligomycin C is a macrolide antibiotic produced by Streptomyces strains. Oligomycin C exhibits a strong activity against Aspergillus niger, Alternaria alternata, Botrytis cinerea and Phytophthora capsici but no activity toward bacteria .

HY-B0133R

Natamycin (Standard) Pimaricin (Standard)	Reference Standards Fungal Endogenous Metabolite Antibiotic Bacterial	Infection
Natamycin (Standard) is the analytical standard of Natamycin. This product is intended for research and analytical applications. Natamycin (Pimaricin) is a macrolide antibiotic agent produced by several Streptomyces strains. Natamycin inhibits the growth of fungi via inhibition of amino acid and glucose transport across the plasma membrane. Natamycin is a food preservative, an antifungal agent in agriculture, and is widely used for fungal keratitis research .

HY-126479

Carbomycin B Magnamycin B	Antibiotic	Infection Inflammation/Immunology
Carbomycin B is a macrolide antibiotic .

HY-N7112A

Leucomycin tartrate Kitasamycin tartrate	Antibiotic Bacterial	Infection
Leucomycin tartrate (Kitasamycin tartrate) is a potent 16-membered macrolideantibiotic .

HY-107213

Tulathromycin B CP 547272	Antibiotic Bacterial	Infection
Tulathromycin B (CP 547272) is an isomer of Tulathromycin (a macrolide antibiotic) .

HY-101411R

4-Acetamidobutanoic acid (Standard) N-acetyl GABA (Standard)	Reference Standards GABA Receptor Endogenous Metabolite Bacterial	Others
Josamycin propionate (Standard) is the analytical standard of Josamycin propionate. This product is intended for research and analytical applications. Josamycin propionate is classified as a macrolide antibiotic.

HY-B0435R

Roxithromycin (Standard) RU-28965 (Standard)	Reference Standards Bacterial Antibiotic	Infection
Roxithromycin (Standard) is the analytical standard of Roxithromycin. This product is intended for research and analytical applications. Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic.

HY-116010A

Oleandomycin phosphate	Antibiotic Bacterial	Infection
Oleandomycin phosphate is a macrolide antibiotic structurally closely related to Erythromycin. Oleandomycin is similar to Erythromycin with antimicrobial activity. Oleandomycin inhibits protein synthesis by interference with translation of activated amino acids to nascent peptide chains on the ribosomes .

HY-126906R

Milbemycin A4 (Standard)	Reference Standards Antibiotic P-glycoprotein	Cancer
Milbemycin A4 (Standard) is the analytical standard of Milbemycin A4. This product is intended for research and analytical applications. Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity sup> .

HY-126813

Concanamycin C	Antibiotic Fungal	Infection
Concanamycin C is a macrolide antibiotic with inhibitory activity against certain fungi and yeasts, but no activity against bacteria. Concanamycin C inhibits the proliferation of mouse splenic lymphocytes. Concanamycin C exhibits acute toxicity in ddY mice. Concanamycin C can be used in studies related to fungal infections and yeast infections .

HY-W055872

Erythromycylamine	Antibiotic	Infection
Erythromycylamine is a macrolide antibiotic. Erythromycylamine has antibacterial activity against most Gram-positive cocci and M. catarrhalis .

HY-N7141R

Spiramycin I (Standard)	Reference Standards Antibiotic Parasite Bacterial	Infection
Spiramycin I (Standard) is the analytical standard of Spiramycin I. This product is intended for research and analytical applications. Spiramycin I is a macrolide antibiotic and antiparasitic .

HY-103250

PF-945863	Antibiotic	Infection
PF-945863 is an orally active macrolide antibiotic that can be used for the research of multidrug resistant respiratory tract bacterial strains .

HY-B1921

Miocamycin Midecamycin acetate; Ponsinomycin	Bacterial	Infection
Miocamycin (Midecamycin acetate) is a derivative of midecamycin (HY-B1908), a macrolide antibiotic that can be isolated from a culture broth of Streptomyces mycarofaciens. Miocamycin has antibacterial properties .

HY-125637

Venturicidin B Aabomycin A2	Antibiotic Fungal ATP Synthase	Infection
Venturicidin B (Aabomycin A2) is a macrolide antibiotic isolated from Streptomyces sp., used as an antifungal agent, a potent inhibitor of the mitochondrial F0-ATP synthase complex .

HY-125652

Macrosphelide A	Antibiotic	Infection
Macrosphelide A is a macrolide antibiotic. Macrosphelide A inhibits growth of some ascomycetes, basidiomycetes, oomycetes and all four Gram-positive bacteria tested, including the medically important Staphylococcus aureus with a MIC of ≤500 μg/mL .

HY-15662R

Tulathromycin A (Standard) Tulathromycin (Standard); CP 472295 (Standard)	Reference Standards Antibiotic Bacterial	Infection
Tulathromycin A (Standard) is the analytical standard of Tulathromycin A. This product is intended for research and analytical applications. Tulathromycin A (Tulathromycin), a macrolide antibiotic, inhibits protein synthesis (IC50=0.26 μM) by targeting bacterial ribosome. Tulathromycin A is used for the research of respiratory disease in cattle and swine. Immunomodulatory effects .

HY-105213

YM-17K MC-352	Antibiotic Bacterial	Infection
YM-17K (MC-352) is a macrolide antibiotic. YM-17K exhibits antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and anaerobic bacteria. YM-17K exhibits stable activity in serum and is less affected by pH values .

HY-129475

Mycinamicin I	Antibiotic	Infection
Mycinamicin I is classified as a macrolide antibiotic.

HY-125561

Josamycin propionate	Antibiotic	Others
Josamycin propionate is classified as a macrolide antibiotic.

HY-N8381

Berkeleylactone E	Antibiotic	Infection
Berkeleylactone E is a macrolide antibiotic .

HY-117849

Neutramycin	Antibiotic	Infection
Neutramycin is a neutral macrolide antibiotic with a complex composition and classification .

HY-N14691

Platenomycin C3	Antibiotic Bacterial	Infection
Platenomycin C3 is a macrolide antibiotic with anti-Gram-positive bacteria effects .

HY-N14456

Platenomycin A0	Antibiotic Bacterial	Infection
Platenomycin A0 is a macrolide antibiotic with anti-Gram-positive bacteria activities .

HY-N14457

Platenomycin W2	Antibiotic Bacterial	Infection
Platenomycin W2 is a macrolide antibiotic with anti-Gram-positive bacteria activities .

HY-119405

Niddamycin	Antibiotic Bacterial	Infection Inflammation/Immunology
Niddamycin, a macrolide antibiotic, binds 50S ribosomal subunits to inhibit protein synthesis .

Cat. No.	Product Name	Target	Research Area

HY-N11615R

Cyclo(Pro-Val) (Standard)	Peptides Reference Standards	Others
Tylosin (tartrate) (Standard) is the analytical standard of Tylosin (tartrate). This product is intended for research and analytical applications. Tylosin tartrate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin tartrate is widely used as a feed additive for promoting animal growth. Tylosin tartrate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-100558

Bafilomycin A1 Maximum Cited Publications 802 Publications Verification BafA1	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Disease Research Anticancer Disease Research Fields Source Classification	Proton Pump Autophagy Antibiotic Bacterial Apoptosis
Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H ⁺-ATPase (V-ATPase) with IC₅₀ values of 4-400 nmol/mg. Bafilomycin A1, a macrolide antibiotic, is also used as an autophagy inhibitor at the late stage. Bafilomycin A1 blocks autophagosome-lysosome fusion and inhibits acidification and protein degradation in lysosomes of cultured cells. Bafilomycin A1 induces apoptosis .

HY-N1724

Concanamycin A 25+ Cited Publications Antibiotic X 4357B; Folimycin; X 4357B	Infection Natural Products Microorganisms Classification of Application Fields Disease Research Fields Source Classification	Proton Pump Bacterial Antibiotic
Concanamycin A (Folimycin; Antibiotic X 4357B) is a macrolide antibiotic, a vacuolar type H ⁺-ATPase (V-ATPase) inhibitor. Concanamycin A is also an inhibitor of lysosomal acidification, can be used to T cell-mediated inflammation research ^- .

HY-B0220

Erythromycin 20+ Cited Publications	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research Anticancer Disease Research Fields Source Classification	Bacterial Antibiotic DNA/RNA Synthesis
Erythromycin is a macrolide antibiotic produced by actinomycete?Streptomyces erythreus?with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits?RNA-dependent protein synthesis?by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid ^[1][2]. Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research ^[3][4].

HY-B0133

Natamycin 5+ Cited Publications Pimaricin	Structural Classification Preservatives Anti-inflammation/Immunoregulatory Antifungal Classification of Application Fields Disease Research Endogenous metabolite Food Research Infection Microorganisms Macrolide Antibiotics Antibiotics Disease Research Fields Source Classification	Environmental Pollutants Antibiotic Endogenous Metabolite Fungal Bacterial
Natamycin (Pimaricin) is a macrolide antibiotic agent produced by several Streptomyces strains. Natamycin inhibits the growth of fungi via inhibition of amino acid and glucose transport across the plasma membrane. Natamycin is a food preservative, an antifungal agent in agriculture, and is widely used for fungal keratitis research .

HY-100593

Spiramycin 1 Publications Verification Rovamycin	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Anti-parasitic Antibacterial Disease Research Disease Research Fields Source Classification	Bacterial Parasite Antibiotic
Spiramycin (Rovamycin) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect. Spiramycin is composed of a 16-member lactone ring, on which three sugars (mycaminose, forosamine, and mycarose) are attached .

HY-B0519A

Tylosin 1 Publications Verification	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields Source Classification	Bacterial Antibiotic
Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-B1920

Josamycin 1 Publications Verification EN-141	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Source Classification	Bacterial Antibiotic
Josamycin (EN-141) is an orally active macrolide antibiotic exhibiting antimicrobial activity against a wide spectrum of pathogens, such as bacteria. The dissociation constant K_d from ribosome for Josamycin is 5.5 nM .

HY-N6742

Borrelidin 1 Publications Verification Treponemycin	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Anti-parasitic Antibacterial Disease Research Disease Research Fields Source Classification	CDK Parasite Apoptosis Antibiotic
Borrelidin (Treponemycin) is a bacterial and eukaryal threonyl-tRNA synthetase inhibitor which is a nitrile-containing macrolide antibiotic isolated from Streptomyces rochei . Borrelidin is an inhibitor of Cdc28/Cln2 of the budding yeast, with an IC₅₀ of 24 μM . Borrelidin is a potent angiogenesis inhibitor, with an IC₅₀ of 0.8 nM. Borrelidin induces apoptosis in the tube-forming cells . Borrelidin has strong antimalarial activities, with IC₅₀s of 1.9 nM and 1.8 nM against K1 and FCR3 strains of Plasmodium falciparum, respectively .

HY-N7112

Leucomycin 1 Publications Verification Kitasamycin	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Source Classification	Bacterial Antibiotic
Leucomycin (Kitasamycin) is an orally active macrolide antibiotic produced by Streptomyces kitasatoensis. Leucomycin has broad-spectrum antibacterial activities against gram-positive and gram-negative bacteria, mycoplasma, leptospira, spirochaetes, rickettsiae and some larger viruses .

HY-N7121

Erythromycin estolate 1 Publications Verification	Infection Microorganisms Anti-inflammation/Immunoregulatory Macrolide Antibiotics Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Source Classification	Antibiotic Bacterial Aminotransferases (Transaminases) Flavivirus Dengue Virus
Erythromycin estolate is the Erythromycin (HY-B0220) derivative , is a macrolide antibiotic used in the treatment of a wide variety of bacterial infections. Erythromycin estolate causes several cases of liver injury which mostly include cholestatic hepatitis. Erythromycin estolate toxicity is related to its inhibitory effect on bile acid transport .

HY-B0519

Tylosin tartrate 1 Publications Verification	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields Source Classification	Bacterial Antibiotic
Tylosin tartrate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin tartrate is widely used as a feed additive for promoting animal growth. Tylosin tartrate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-B0220D

Erythromycin thiocyanate 20+ Cited Publications	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Antibacterial Disease Research Anticancer Disease Research Fields Source Classification	Bacterial Antibiotic DNA/RNA Synthesis
Erythromycin thiocyanate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin thiocyanate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid ^[1][2]. Erythromycin thiocyanate also exhibits antitumor and neuroprotective effect in different fields of research ^[3][4].

HY-B1908

Midecamycin 2 Publications Verification SF-837; Antibiotic SF-837	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Source Classification	Bacterial Antibiotic
Midecamycin, an acetoxy-substituted macrolide antibiotic, is tested against gram-positive and gram-negative bacteria.

HY-B0519B

Tylosin phosphate 1 Publications Verification	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Animal Husbandry Antibacterial Disease Research Disease Research Fields Source Classification	Bacterial Antibiotic
Tylosin phosphate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin phosphate is widely used as a feed additive for promoting animal growth. Tylosin phosphate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-N7141

Spiramycin I 1 Publications Verification	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Anti-parasitic Disease Research Disease Research Fields Source Classification	Antibiotic Parasite Bacterial
Spiramycin I is a macrolide antibiotic and antiparasitic .

HY-106681

Lagosin Fungichromin; Pentamycin; Cogomycin	Microorganisms Antifungal Macrolide Antibiotics Classification of Application Fields Antibiotics Disease Research Disease Research Fields Source Classification Cancer	Antibiotic Fungal
Lagosin (Fungichromin) is a polyene macrolide antibiotic. Lagosin has demonstrated broad-spectrum antifungal activity and is impervious to agent resistance .

HY-130173

Bafilomycin C1 1 Publications Verification	Infection Microorganisms Macrolide Antibiotics Antibiotics Antibacterial Disease Research Anticancer Disease Research Fields Source Classification Cancer	Bacterial Fungal Na+/K+ ATPase Apoptosis Antibiotic
Bafilomycin C1 is a macrolide antibiotic isolated from Streptomyces sp. Bafilomycin C1 is a potent, specific and reversible inhibitor of vacuolar-type H ⁺-ATPases (V-ATPases). Bafilomycin C1 inhibits growth of gram-positive bacteria and fungi . Bafilomycin C1 induces cell apoptosis and can be used for the study of hepatocellular carcinoma (HCC) .

HY-N6738

Bafilomycin B1 1 Publications Verification	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Source Classification	Antibiotic Bacterial Fungal Proton Pump
Bafilomycin B1 is a *macrolide antibiotic* that can be isolated from mycelium of Streptomyces gresuis. Bafilomycin B1 is neuroprotective against Chloroquine (HY-17589A)-induced death. Bafilomycin B1 is a structural analog of Bafilomycin A1 and has the ability to inhibit V-ATPase. Bafilomycin B1 inhibits significantly the oxidized low density lipoprotein (LDL)-induced accumulation of lipid droplets .

HY-120809

Spiramycin III	Microorganisms Macrolide Antibiotics Antibiotics Source Classification	Bacterial Parasite Antibiotic
Spiramycin III (SPMIII) is a main component of Spiramycin. Spiramycin (HY-100593) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect .

HY-N6783

Oligomycin C 1 Publications Verification	Infection Microorganisms Antifungal Macrolide Antibiotics Classification of Application Fields Antibiotics Disease Research Disease Research Fields Source Classification	Fungal Antibiotic
Oligomycin C is a macrolide antibiotic produced by Streptomyces strains. Oligomycin C exhibits a strong activity against Aspergillus niger, Alternaria alternata, Botrytis cinerea and Phytophthora capsici but no activity toward bacteria .

HY-B0133R

Natamycin (Standard) Pimaricin (Standard)	Structural Classification Microorganisms Anti-inflammation/Immunoregulatory Antifungal Macrolide Antibiotics Antibiotics Disease Research Endogenous metabolite Source Classification	Reference Standards Fungal Endogenous Metabolite Antibiotic Bacterial
Natamycin (Standard) is the analytical standard of Natamycin. This product is intended for research and analytical applications. Natamycin (Pimaricin) is a macrolide antibiotic agent produced by several Streptomyces strains. Natamycin inhibits the growth of fungi via inhibition of amino acid and glucose transport across the plasma membrane. Natamycin is a food preservative, an antifungal agent in agriculture, and is widely used for fungal keratitis research .

HY-126479

Carbomycin B Magnamycin B	Microorganisms Macrolide Antibiotics Antibiotics Source Classification	Antibiotic
Carbomycin B is a macrolide antibiotic .

HY-N7112A

Leucomycin tartrate Kitasamycin tartrate	Natural Products Animals Source Classification	Antibiotic Bacterial
Leucomycin tartrate (Kitasamycin tartrate) is a potent 16-membered macrolideantibiotic .

HY-101411R

4-Acetamidobutanoic acid (Standard) N-acetyl GABA (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards GABA Receptor Endogenous Metabolite Bacterial
Josamycin propionate (Standard) is the analytical standard of Josamycin propionate. This product is intended for research and analytical applications. Josamycin propionate is classified as a macrolide antibiotic.

HY-126813

Concanamycin C	Structural Classification Natural Products Microorganisms Source Classification	Antibiotic Fungal
Concanamycin C is a macrolide antibiotic with inhibitory activity against certain fungi and yeasts, but no activity against bacteria. Concanamycin C inhibits the proliferation of mouse splenic lymphocytes. Concanamycin C exhibits acute toxicity in ddY mice. Concanamycin C can be used in studies related to fungal infections and yeast infections .

HY-B0519BR

Tylosin phosphate (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Animal Husbandry Antibacterial Disease Research Source Classification	Reference Standards Bacterial Antibiotic
Tylosin (phosphate) (Standard) is the analytical standard of Tylosin (phosphate). This product is intended for research and analytical applications. Tylosin phosphate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin phosphate is widely used as a feed additive for promoting animal growth. Tylosin phosphate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-N7141R

Spiramycin I (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Anti-parasitic Disease Research Source Classification	Reference Standards Antibiotic Parasite Bacterial
Spiramycin I (Standard) is the analytical standard of Spiramycin I. This product is intended for research and analytical applications. Spiramycin I is a macrolide antibiotic and antiparasitic .

HY-125652

Macrosphelide A	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Source Classification	Antibiotic
Macrosphelide A is a macrolide antibiotic. Macrosphelide A inhibits growth of some ascomycetes, basidiomycetes, oomycetes and all four Gram-positive bacteria tested, including the medically important Staphylococcus aureus with a MIC of ≤500 μg/mL .

HY-112661

PC-766B Antibiotic PC-766B	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Disease Research Fields Source Classification Cancer	Antibiotic Bacterial Fungal
PC-766B is a macrolide antibiotic. PC-766B is active against Gram-positive bacteria, and some fungi and yeasts, but inactive against Gram-negative bacteria. PC-766B shows antitumor activity against murine tumor cells. PC-766B has weak inhibitory activity against Na ⁺, K ⁺-ATPase .

HY-B0519AR

Tylosin (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research Source Classification	Reference Standards Bacterial Antibiotic
Tylosin (Standard) is the analytical standard of Tylosin. This product is intended for research and analytical applications. Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-N7454

Anhydroerythromycin A	Infection Structural Classification Macrolide Antibiotics Classification of Application Fields Antibiotics Antibacterial Disease Research Endogenous metabolite Disease Research Fields Source Classification	Drug Metabolite Bacterial
Anhydroerythromycin A is a degradation product of the macrolide antibiotic erythromycin. Anhydroerythromycin A is formed via degradation of erythromycin in acidic aqueous solutions in vitro as well as in vivo. Anhydroerythromycin A is active against S. aureus and B. cereus in vitro (MICs = 12.5 and 6.25 μg/ml, respectively). Anhydroerythromycin A also inhibits steroid 6β-hydroxylase activity associated with the cytochrome P450 (CYP) isoform CYP3A in human liver microsomes.

HY-B0220R

Erythromycin (Standard) 20+ Cited Publications	Structural Classification Classification of Application Fields Antibacterial Disease Research Infection Microorganisms Macrolide Antibiotics Antibiotics Animal Husbandry Mammalian Cell Culture Anticancer Disease Research Fields Source Classification	Reference Standards Bacterial Antibiotic DNA/RNA Synthesis
Erythromycin (Standard) is the analytical standard of Erythromycin. This product is intended for research and analytical applications. Erythromycin is a macrolide antibiotic produced by actinomycete?Streptomyces erythreus?with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits?RNA-dependent protein synthesis?by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid . Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research .

HY-B0519R

Tylosin tartrate (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research Source Classification	Reference Standards Bacterial Antibiotic
Tylosin (tartrate) (Standard) is the analytical standard of Tylosin (tartrate). This product is intended for research and analytical applications. Tylosin tartrate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin tartrate is widely used as a feed additive for promoting animal growth. Tylosin tartrate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-N8381

Berkeleylactone E	Microorganisms Macrolide Antibiotics Antibiotics Source Classification	Antibiotic
Berkeleylactone E is a macrolide antibiotic .

HY-N14691

Platenomycin C3	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial
Platenomycin C3 is a macrolide antibiotic with anti-Gram-positive bacteria effects .

HY-N14456

Platenomycin A0	Microorganisms Ketones, Aldehydes, Acids Source Classification	Antibiotic Bacterial
Platenomycin A0 is a macrolide antibiotic with anti-Gram-positive bacteria activities .

HY-N14457

Platenomycin W2	Microorganisms Ketones, Aldehydes, Acids Source Classification	Antibiotic Bacterial
Platenomycin W2 is a macrolide antibiotic with anti-Gram-positive bacteria activities .

HY-N14505

Mycinamicin Ⅵ	Microorganisms Macrolide Antibiotics Antibiotics Source Classification	Antibiotic Bacterial
Mycinamicin VI is a macrolide antibiotic. Mycinamicin VI shows activity against Gram-positive bacteria .

HY-N14507

Mycinamicin VII	Microorganisms Macrolide Antibiotics Antibiotics Source Classification	Antibiotic Bacterial
Mycinamicin VII is a macrolide antibiotic. Mycinamicin VII shows activity against Gram-positive bacteria .

HY-125707

Concanamycin B MCH 210	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source Classification	Proton Pump Antibiotic
Concanamycin B is a macrolide antibiotic, which can inhibit the cavitation type H+-ATPases, and the IC₅₀ value is 5 nM .

HY-115367

Aldgamycin G	Microorganisms Antibiotics Source Classification	Antibiotic Bacterial
Aldgamycin G is a macrolide antibiotic active against Gram-positive bacteria and can be isolated from Streptomyces avidinii .

HY-N15075

Espinomycin A2	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source Classification	Antibiotic Bacterial
Espinomycin A2 is a sixteen-membered macrolide antibiotic. Espinomycin A2 is active against Gram-positive bacteria .

HY-N15032

Espinomycin A3	Microorganisms Macrolide Antibiotics Antibiotics Source Classification	Antibiotic Bacterial
Espinomycin A3 is a sixteen-membered macrolide antibiotic. Espinomycin A3 is active against Gram-positive bacteria .

HY-113795

Aldgamycin E	Microorganisms Antibiotics Source Classification	Antibiotic Bacterial
Aldgamycin E is a neutral macrolide antibiotic that can be derived from culture filtrates of Streptomyces lavendulae. Aldgamycin E has antibacterial activity .

HY-N14191

Malonylniphimycin	Microorganisms Antibiotics Cyclopeptides Source Classification	Antibiotic Bacterial Fungal
Malonylniphimycin is a macrolide antibiotic found in Streptomyces str. hygroscopicus B-7. Malonylniphimycin is resistant to Gram-positive bacteria, fungi and yeasts .

HY-151224R

Thermospermine (Standard)	Microorganisms Source Classification	DNA/RNA Synthesis Reference Standards
Roxithromycin (Standard) is the analytical standard of Roxithromycin. This product is intended for research and analytical applications. Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic.

HY-N15090

Milbemycin α10	Microorganisms Antibiotics Source Classification	Antibiotic Bacterial Insecticide
Milbemycin α10 is a macrolide antibiotic. Milbemycin α10 has insecticidal effects on agricultural harmful insects, pans, larvae, etc .

HY-N14860

Milbemycin β3	Natural Products Microorganisms Source Classification	Antibiotic Bacterial
Milbemycin β3 is a macrolide antibiotic. Milbemycin β3 has insecticidal effects on agricultural harmful insects, pans, larvae, etc .

HY-N14762

Leucomycin V	Microorganisms Macrolide Antibiotics Antibiotics Source Classification	Antibiotic Bacterial
Leucomycin V is a macrolide antibiotic. Leucomycin V has strong anti-Gram-positive bacterial effect, and also has an effect on spirochetes, Rickettsium and Chlamydia .

HY-N12421

Paulomycin A Volonomycin A	Microorganisms Antibiotics Source Classification	Bacterial
Paulomycin A (Volonomycin A) has anti-Gram-positive bacteria effect, and it has inhibitory effect on Staphylococcus aureus resistant to penicillin, Streptomycin, Neomycin and Macrolide antibiotics .

Cat. No.	Product Name	Chemical Structure

HY-17506S

Azithromycin-d3
Azithromycin-d₃ is the deuterium labeled Azithromycin. Azithromycin (CP-62993) is a macrolide antibiotic useful for the treatment of a number of bacterial infections .

HY-B0435S

Roxithromycin-d7
Roxithromycin-d₇ (RU-28965-d₇) is the deuterium labeled Roxithromycin (HY-B0435) . Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic .

HY-B0220S1

Erythromycin-13C,d3

Erythromycin- ¹³C,d₃ is the ¹³C- and deuterium labeled Erythromycin. Erythromycin is a macrolide antibiotic produced by actinomycete?Streptomyces erythreus?with a broad spectrum of antimicrobial activity. Erythromycin acts by binding to bacterial 50S ribosomal subunits and inhibits?RNA-dependent protein synthesis?by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid .

HY-B0519AS

Tylosin-d3

Tylosin-d₃ is the deuterium labeled Tylosin. Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .

HY-B0220S2

Erythromycin-d3

Erythromycin-d₃ is the deuterium labeled Erythromycin . Erythromycin is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid. Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research .

HY-B0905S

Tilmicosin-d3

Tilmicosin-d3 is the deuterium labeled Tilmicosin. Tilmicosin (LY-177370) is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. Tilmicosin mainly acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin is effective in the treatment of respiratory diseases in livestock such as cattle, sheep and pigs. In addition, Tilmicosin has immunomodulatory and anti-inflammatory effects .

HY-B0220S3

Erythromycin-13C2
Erythromycin-13C2 is a macrolide antibiotic that can be used to treat respiratory infections, skin infections, and chlamydia infections .

HY-W710036

Erythromycin A 9-oxime-d3
Erythromycin A 9-oxime-d₃ is the deuterium labeled Erythromycin oxime (HY-134518). Erythromycin oxime is an intermediate of Azithromycin (HY-17506). Azithromycin is a macrolide antibiotic useful for the treatment of a number of bacterial infections.

HY-W653875

Azithromycin-d5
Azithromycin-d₅ (CP-62993-d₅) is the deuterium labeled Azithromycin (CP-62993) (HY-17506) . Azithromycin is a macrolide antibiotic useful for thestudy of a number of bacterial infections .

HY-B0220S

Erythromycin-d6

Erythromycin-d₆ is the deuterium labeled Erythromycin. Erythromycin is a macrolide antibiotic produced by actinomycete?Streptomyces erythreus?with a broad spectrum of antimicrobial activity. Erythromycin acts by binding to bacterial 50S ribosomal subunits and inhibits?RNA-dependent protein synthesis?by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid .

HY-15662S

Tulathromycin A-d7
Tulathromycin A-d₇ (Tulathromycin-d₇) is deuterium labeled Tulathromycin A. Tulathromycin A (Tulathromycin), a macrolide antibiotic, inhibits protein synthesis (IC₅₀=0.26 μM) by targeting bacterial ribosome. Tulathromycin A is used for the research of respiratory disease in cattle and swine. Immunomodulatory effects .

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