Concanamycin C

Cat. No.: HY-126813 Purity: 99.9%: Data Sheet
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Concanamycin C is a macrolide antibiotic with inhibitory activity against certain fungi and yeasts, but no activity against bacteria. Concanamycin C inhibits the proliferation of mouse splenic lymphocytes. Concanamycin C exhibits acute toxicity in ddY mice. Concanamycin C can be used in studies related to fungal infections and yeast infections.

For research use only. We do not sell to patients.

Concanamycin C Chemical Structure

CAS No. : 81552-34-3

Size	Stock	Quantity
25 μg	In-stock	Estimated Time of Arrival: December 31
100 μg	In-stock	Estimated Time of Arrival: December 31
500 μg	Get quote	Estimated Time of Arrival: December 31

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References
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Description

In Vitro

Concanamycin C exhibits in vitro inhibitory activity against specific fungi and yeasts, including Saccharomyces cerevisiae, S. sake, Alternaria citri, Penicillium citrinum, and Pirricularia oryzae, but has no activity against tested bacteria and other fungi/yeasts^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Concanamycin C (0.1-1.0 mg/kg; i.p.; single administration) exhibits acute toxicity in ddY mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	ddY mice^[1]
Dosage:	0.1 mg/kg; 1.0 mg/kg
Administration:	i.p.; single dose
Result:	Resulted in 100% survival in ddY mice. Resulted in 100% mortality in ddY mice.

Molecular Weight

823.06

Formula

C₄₅H₇₄O₁₃

CAS No.

81552-34-3

Appearance

Solid

Color

White to off-white

SMILES

C[C@H](C/C(C)=C\C=C\[C@H](OC)[C@]([C@@H](C)[C@@H](O)[C@H](C)[C@@]1(O)C[C@@H](O[C@@]2([H])C[C@@H](O)[C@H](O)[C@@H](C)O2)[C@H](C)[C@@H](/C=C/C)O1)([H])O3)[C@H](O)[C@H](CC)[C@H](O)[C@H](C)/C=C(C)/C=C(OC)/C3=O

Structure Classification

Others

Initial Source

Microorganisms

Streptomyces diastatochromogenes S-45

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Purity: 99.9%

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Data Sheet (267 KB) SDS (481 KB)

COA (250 KB)

Handling Instructions (2659 KB)

References

[1]. inashi H, et al., Isolation and characterization of concanamycins A, B and C. J Antibiot (Tokyo). 1984 Nov;37(11):1333-43. [Content Brief]

Concanamycin C Related Classifications

Infection

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Concanamycin C81552-34-3AntibioticFungalpokeweed mitogenStreptomyces diastatochromogenes S-45Saccharomyces cerevisiaeddY miceyeastsmixed lymphocyte reactionsconcanavalin Afungibacteriamouse splenic lymphocytesInhibitorinhibitorinhibit

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