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Concanamycin C

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Concanamycin C is a macrolide antibiotic with inhibitory activity against certain fungi and yeasts, but no activity against bacteria. Concanamycin C inhibits the proliferation of mouse splenic lymphocytes. Concanamycin C exhibits acute toxicity in ddY mice. Concanamycin C can be used in studies related to fungal infections and yeast infections.

For research use only. We do not sell to patients.

Purity: 99.9%
CAS No.: 81552-34-3
Formula: C₄₅H₇₄O₁₃
Molecular Weight:823.06

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Concanamycin C Chemical Structure

CAS No.: 81552-34-3

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Quantity

Sample (0.1mg)

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(In Japan)

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

All Antibiotic Isoforms :

In Vitro

Concanamycin C exhibits in vitro inhibitory activity against specific fungi and yeasts, including Saccharomyces cerevisiae, S. sake, Alternaria citri, Penicillium citrinum, and Pirricularia oryzae, but has no activity against tested bacteria and other fungi/yeasts^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Concanamycin C (0.1-1.0 mg/kg; i.p.; single administration) exhibits acute toxicity in ddY mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

ddY mice^[1]
Dosage:

0.1 mg/kg; 1.0 mg/kg
Administration:

i.p.; single dose
Result:

Resulted in 100% survival in ddY mice.
Resulted in 100% mortality in ddY mice.

Chemical Information

CAS No. 81552-34-3
Appearance Solid
Molecular Weight 823.06
Formula C₄₅H₇₄O₁₃
Color White to off-white
SMILES

C[C@H](C/C(C)=C\C=C\[C@H](OC)[C@]([C@@H](C)[C@@H](O)[C@H](C)[C@@]1(O)C[C@@H](O[C@@]2([H])C[C@@H](O)[C@H](O)[C@@H](C)O2)[C@H](C)[C@@H](/C=C/C)O1)([H])O3)[C@H](O)[C@H](CC)[C@H](O)[C@H](C)/C=C(C)/C=C(OC)/C3=O
Structure Classification
- Others
Initial Source
- Microorganisms
Streptomyces diastatochromogenes S-45
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (481 KB)
- English - EN (481 KB)
- Français - FR (481 KB)
- Deutsch - DE (481 KB)
- Norwegian - NO (481 KB)
- Español - ES (481 KB)
- Swedish - SV (481 KB)
- Italian - IT (481 KB)
- Portuguese - PT (481 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. inashi H, et al., Isolation and characterization of concanamycins A, B and C. J Antibiot (Tokyo). 1984 Nov;37(11):1333-43. [Content Brief]

Calculators

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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