1. Anti-infection
  2. Fungal
  3. Natamycin

Natamycin (Synonyms: Pimaricin)

Cat. No.: HY-B0133 Purity: >98.0%
Handling Instructions

Natamycin (pimaricin) is an antifungal macrolide polyene that binds to cell membrane sterols.

For research use only. We do not sell to patients.

Natamycin Chemical Structure

Natamycin Chemical Structure

CAS No. : 7681-93-8

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
50 mg USD 60 In-stock
Estimated Time of Arrival: December 31
100 mg USD 96 In-stock
Estimated Time of Arrival: December 31
200 mg USD 174 In-stock
Estimated Time of Arrival: December 31
500 mg USD 360 In-stock
Estimated Time of Arrival: December 31
1 g   Get quote  
5 g   Get quote  

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Description

Natamycin (pimaricin) is an antifungal macrolide polyene that binds to cell membrane sterols. Target: Antifungal Natamycin (INN), also known as pimaricin and sometimes sold as Natacyn, is a naturally occurring antifungal agent produced during fermentation by the bacterium Streptomyces natalensis, commonly found in soil. Natamycin has a very low solubility in water; however, natamycin is effective at very low levels. There is an MIC (minimum inhibitory concentration) of less than 10 ppm for most molds. Natamycin is classified as a macrolide polyene antifungal and, as a drug, is used to treat fungal keratitis. It is especially effective against Aspergillus and Fusarium corneal infections. Other common members of the polyene macrolide antifungal family are amphotericin B, nystatin, and filipin. Natamycin is also used in the food industry as a natural preservative. Natamycin is used to treat fungal infections, including Candida, Aspergillus, Cephalosporium, Fusarium and Penicillium. It is applied as a cream, in eyedrops, or (for oral infections) in a lozenge. Natamycin shows negligible absorption into the body when administered in these ways. When taken orally, little or none is absorbed from the gastrointestinal tract, making it inappropriate for systemic infections.

Clinical Trial
Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 10.75 mg/mL (16.15 mM; Need warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5021 mL 7.5106 mL 15.0211 mL
5 mM 0.3004 mL 1.5021 mL 3.0042 mL
10 mM 0.1502 mL 0.7511 mL 1.5021 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

665.73

Formula

C₃₃H₄₇NO₁₃

CAS No.

7681-93-8

SMILES
Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
Natamycin
Cat. No.:
HY-B0133
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Natamycin

Cat. No.: HY-B0133