Erythromycin A enol ether
Based on 1 Customer Validation
Erythromycin A enol ether is an acidic degradation product of Erythromycin A (macrolide antibiotic) and has no antibacterial effect.
For research use only. We do not sell to patients.
- Purity: 98.86%
- CAS No.: 33396-29-1
- Formula: C37H65NO12
- Molecular Weight:715.91
-
Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
-
Anti-Infection Compound Library
HY-L002
-
Macrocyclic Compound Library
HY-L041
-
Antibacterial Compound Library
HY-L049
-
Antibiotics Library
HY-L067
-
Human Metabolite Library
HY-L123
-
Heterocyclic Compound Library
HY-L138
-
Bioactive Compound Library Max
HY-L181
-
MCE Bioactive Compound Library
HY-L001V
-
Bioactive Compound Library
HY-L001
-
High-Throughput Bioactive Compound Library
HY-L205
-
Mass Spectrometry Human Metabolite Library
HY-L215
All Antibiotic Isoforms
More
Biological Activity
Chemical Information
-
CAS No. 33396-29-1
-
Appearance Solid
-
Molecular Weight 715.91
-
Formula C37H65NO12
-
Color White to off-white
-
SMILES
C[C@@](OC([C@@H]([C@H]([C@](O)1C)O)C)=C2C)(C2)[C@@H]([C@H]([C@@H]([C@H](C(O[C@@H]1CC)=O)C)O[C@H](O[C@H]3C)C[C@](C)([C@H]3O)OC)C)O[C@H](O[C@@H]4C)[C@@H]([C@H](C4)N(C)C)O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (139.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
-
-
-
-
Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
-
%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
-
%+
-
+%Tween-80 + +
-
%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
-
Data Sheet (281 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
[1]. A Deubel, et al. Development of an enhanced separation of erythromycin and its related substances by liquid chromatography. J Pharm Biomed Anal. 2007 Jan 17;43(2):493-8. [Content Brief]
[2]. Abdolreza Hassanzadeh, et al. Mechanism for the degradation of erythromycin A and erythromycin A 2'-ethyl succinate in acidic aqueous solution. J Phys Chem A. 2007 Oct 11;111(40):10098-104. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3968 mL | 6.9841 mL | 13.9682 mL | 34.9206 mL |
| 5 mM | 0.2794 mL | 1.3968 mL | 2.7936 mL | 6.9841 mL | |
| 10 mM | 0.1397 mL | 0.6984 mL | 1.3968 mL | 3.4921 mL | |
| 15 mM | 0.0931 mL | 0.4656 mL | 0.9312 mL | 2.3280 mL | |
| 20 mM | 0.0698 mL | 0.3492 mL | 0.6984 mL | 1.7460 mL | |
| 25 mM | 0.0559 mL | 0.2794 mL | 0.5587 mL | 1.3968 mL | |
| 30 mM | 0.0466 mL | 0.2328 mL | 0.4656 mL | 1.1640 mL | |
| 40 mM | 0.0349 mL | 0.1746 mL | 0.3492 mL | 0.8730 mL | |
| 50 mM | 0.0279 mL | 0.1397 mL | 0.2794 mL | 0.6984 mL | |
| 60 mM | 0.0233 mL | 0.1164 mL | 0.2328 mL | 0.5820 mL | |
| 80 mM | 0.0175 mL | 0.0873 mL | 0.1746 mL | 0.4365 mL | |
| 100 mM | 0.0140 mL | 0.0698 mL | 0.1397 mL | 0.3492 mL |
Erythromycin A enol ether Related Classifications
HY-122207 Related Classifications
Powered by Bioz