2. Anti-infection Cell Cycle/DNA Damage
  3. Bacterial Antibiotic DNA/RNA Synthesis
  4. Erythromycin (glutamate)

Erythromycin glutamate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin glutamate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1][2]. Erythromycin glutamate also exhibits antitumor and neuroprotective effect in different fields of research[3][4].

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CAS No. : 16667-03-1

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Top Publications Citing Use of Products

    Erythromycin (glutamate) purchased from MedChemExpress. Usage Cited in: AMB Express. 2024 Dec 24;14(1):141.  [Abstract]

    Combinational antimicrobial effects between PVB and conventional antibiotics against MRSA ATCC 43,300. TET, Tetracycline. DOX, Doxycycline. E, Erythromycin. AZI, Azithromycin. P, Penicillin. CAZ, Ceftazidime. AMP, Ampicillin. CEZ, Cefazolin. CEF, Cefotaxime. OXA, Oxacillin. CRO, Ceftriaxone. AMK, Amikacin. GEN, Gentamycin, KANA, Kanamycin. TOB, Tobramycin. SPC, Spectinomycin.

    Erythromycin (glutamate) purchased from MedChemExpress. Usage Cited in: Theranostics. 2022 Jan 1;12(3):1187-1203.  [Abstract]

    mRNA levels of thermogenic and mitochondrial gene programs in immortal beige and brown adipocytes treated with controls,erythromycin, azithromycin roxithromycin and telithromyc at 5 uM for 24 h (n=3).

    Erythromycin (glutamate) purchased from MedChemExpress. Usage Cited in: EBioMedicine. 2022 Apr;78:103943.  [Abstract]

    FIC indices of the combination of plumbagin (32 μg/mL) and Erythromycin against tet(X3)/tet(X4)-positive strains. Synergy was defined as an FIC index of ≤ 0.5.

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    Description

    Erythromycin glutamate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin glutamate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1][2]. Erythromycin glutamate also exhibits antitumor and neuroprotective effect in different fields of research[3][4].

    Molecular Weight

    881.06

    Formula

    C42H76N2O17
    CAS No.
    SMILES

    OC(CC[C@H](N)C(O)=O)=O.C[C@@H]([C@@H]([C@H](C(O[C@@H]([C@@](O)([C@@H]([C@H](C([C@@H](C[C@]1(O)C)C)=O)C)O)C)CC)=O)C)O[C@H]2C[C@](C)([C@H]([C@@H](O2)C)O)OC)[C@H]1O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
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    Erythromycin (glutamate) Related Classifications

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      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Erythromycin (glutamate)16667-03-1BacterialAntibioticDNA/RNA Synthesisactinomycetestreptomyces antimicrobialprotein synthesistumorcancerEAC P388cellantitumorneuroprotectiveInhibitorinhibitorinhibit

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