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Results for "

Carotenoid

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acetolactate Synthase (ALS) (1) Adiponectin Receptor (1) Androgen Receptor (1) Apoptosis (14) Autophagy (1) Bacterial (4) Bcl-2 Family (1) Biochemical Assay Reagents (7) c-Myc (2) Calcium Channel (1) Caspase (3) Cytochrome P450 (2) Dengue Virus (1) DNA/RNA Synthesis (2) Drug Derivative (17) Drug Intermediate (3) Drug Isomer (2) Drug Metabolite (3) Endogenous Metabolite (23) Environmental Pollutants (5) Epigenetic Reader Domain (1) ERK (2) Fluorescent Dye (1) Heme Oxygenase (HO) (1) Herbicide (12) HPPD (3) Isotope-Labeled Compounds (2) Keap1-Nrf2 (1) MMP (1) NF-κB (1) NO Synthase (2) P-glycoprotein (1) P2X Receptor (1) p38 MAPK (1) Photosystem II (1) PI3K (1) PPAR (4) PROTACs (1) Reactive Oxygen Species (ROS) (14) Reference Standards (10) STAT (1)
By Research Areas:	Cancer (26) Cardiovascular Disease (8) Infection (6) Inflammation/Immunology (20) Metabolic Disease (17) Neurological Disease (4)

By Targets:

Acetolactate Synthase (ALS) (1)

Adiponectin Receptor (1)

Androgen Receptor (1)

Apoptosis (14)

Autophagy (1)

Bacterial (4)

Bcl-2 Family (1)

Biochemical Assay Reagents (7)

c-Myc (2)

Calcium Channel (1)

Caspase (3)

Cytochrome P450 (2)

Dengue Virus (1)

DNA/RNA Synthesis (2)

Drug Derivative (17)

Drug Intermediate (3)

Drug Isomer (2)

Drug Metabolite (3)

Endogenous Metabolite (23)

Environmental Pollutants (5)

Epigenetic Reader Domain (1)

ERK (2)

Fluorescent Dye (1)

Heme Oxygenase (HO) (1)

Herbicide (12)

HPPD (3)

Isotope-Labeled Compounds (2)

Keap1-Nrf2 (1)

MMP (1)

NF-κB (1)

NO Synthase (2)

P-glycoprotein (1)

P2X Receptor (1)

p38 MAPK (1)

Photosystem II (1)

PI3K (1)

PPAR (4)

PROTACs (1)

Reactive Oxygen Species (ROS) (14)

Reference Standards (10)

STAT (1)

By Research Areas:

Cancer (26)

Cardiovascular Disease (8)

Infection (6)

Inflammation/Immunology (20)

Metabolic Disease (17)

Neurological Disease (4)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0287

Lycopene Maximum Cited Publications 19 Publications Verification	Reactive Oxygen Species (ROS) Endogenous Metabolite	Cardiovascular Disease Cancer
Lycopene is naturally occurring carotenoids found in tomato, tomato products, and in other red fruits and vegetables; exhibits antioxidant effects.

HY-N6947

Lutein 4 Publications Verification Xanthophyll	Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS)	Neurological Disease Inflammation/Immunology
Lutein (Xanthophyll) is a carotenoid with reported anti-inflammatory properties. A large body of evidence shows that lutein has several beneficial effects, especially on eye health . Lutein exerts its biological activities, including anti-inflammation, anti-oxidase and anti-apoptosis, through effects on reactive oxygen species (ROS) . Lutein is able to arrive in the brain and shows antidepressant-like and neuroprotective effects. Lutein is orally active .

HY-B2163

Astaxanthin 15+ Cited Publications	PPAR Reactive Oxygen Species (ROS) STAT NF-κB Apoptosis	Cardiovascular Disease Metabolic Disease Cancer
Astaxanthin, the red dietary carotenoid, is an orally effective and potent antioxidant. Astaxanthin inhibits NF-κB and down-regulates VEGF in blood glucose. Astaxanthin exerts anti-cancer cell proliferation, increases apoptosis, impairs migration and invasion by activating PPARγ and reducing the expression of STAT3. Astaxanthin also has neuroprotective and anti-inflammatory activity and can be used in studies of cancer, diabetic retinopathy, cardiovascular disease, and in the coloring of animal feed .

HY-120318

Zeaxanthin 2 Publications Verification	Endogenous Metabolite	Inflammation/Immunology Cancer
Zeaxanthin, a diet-obtained carotenoid, presents in the macula region of the eye. Zeaxanthin shows antioxidant effects .

HY-N2302

Fucoxanthin 10+ Cited Publications all-trans-Fucoxanthin	Bacterial PPAR c-Myc NO Synthase Caspase ERK	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Fucoxanthin (all-trans-Fucoxanthin) is a marine carotenoid and shows anti-obesity, anti-diabetic, anti-oxidant, anti-inflammatory and anticancer activities .

HY-N0411

β-Carotene 2 Publications Verification Provitamin A; beta-Carotene	Environmental Pollutants Endogenous Metabolite Reactive Oxygen Species (ROS) Apoptosis	Metabolic Disease Cancer
β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .

HY-B1960

Canthaxanthin 3 Publications Verification E 161g; all-trans-Canthaxanthin	Reactive Oxygen Species (ROS) Endogenous Metabolite	Inflammation/Immunology Cancer
Canthaxanthin is a red-orange carotenoid with various biological activities, such as antioxidant, antitumor properties.

HY-N6677

β-Apo-8'-carotenal Apocarotenal	Cytochrome P450 DNA/RNA Synthesis	Metabolic Disease Cancer
β-Apo-8'-carotenal (Apocarotenal), an orally active provitamin A carotenoid. β-Apo-8'-carotenal can induce the expression of CYP1A through the Ah receptor-dependent pathway. β-Apo-8'-carotenal can induce cancer cells DNA strand breaks and lipid peroxidation. β-Apo-8'-carotenal can be used for the researches of cancer and metabolic disease .

HY-N0411R

β-Carotene (Standard) Provitamin A (Standard); beta-Carotene (Standard)	Reference Standards Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS)	Metabolic Disease Cancer
β-Carotene (Standard) is the analytical standard of β-Carotene. This product is intended for research and analytical applications. β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .

HY-107425A

cis-MZ 1	PROTACs Epigenetic Reader Domain	Cancer
cis-MZ 1 is a cis isomer of meso-zeaxanthin, a xanthophyll carotenoid component of total zeaxanthin measured in serum and egg yolks.cis-MZ 1 is a triphenyltin benzoate that adopts either a tetrahedral monomeric structure (I) or a trans-SnR₃O₂ polymeric structure (III), with structure determined by a balance of steric and electronic factors .

HY-N10991

Crocetin dialdehyde	Drug Derivative	Others
Crocetin dialdehyde is a non-volatile apocarotenoid obtained by the action of the plastidic enzyme CCD2 over the carotenoid zeaxanthin in saffron. Crocetin dialdehyde can be converted into Crocetin (HY-N2072) by aldehyde dehydrogenases (ALDHs). Crocetin dialdehyde has no effect on the liver in mice .

HY-108059

β-Cryptoxanthin (3R)-β-Cryptoxanthin	Drug Derivative	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
β-Cryptoxanthin ((3R)-β-Cryptoxanthin) is an orally active carotenoid found in fruits and vegetables such as angerines, red peppers, and pumpkin. β-Cryptoxanthin inhibits prevents osteoclast formation and inhibits bone resorption. β-Cryptoxanthin maintains retinol status in vivo. β-cryptoxanthin shows anti-inflammation and anticancer activity. β-Cryptoxanthin can be used for the researches of osteoporosis and bladder carcer .

HY-N9182

Zeaxanthin dipalmitate Physalien	Adiponectin Receptor P2X Receptor Autophagy	Inflammation/Immunology
Zeaxanthin dipalmitate (Physalien) is a wolfberry-derived carotenoid, has anti-inflammatory and anti-oxidative stress effects. Zeaxanthin dipalmitate directly interact with p2X7 receptor (K_d=81.2 nM) and adiponectin receptor 1 (AdipoR1; K_d=533 nM) in a positive dose-dependent manner. Zeaxanthin dipalmitate restores mitochondrial autophagy functions suppressed by ethanol intoxication. Zeaxanthin dipalmitate can be used in the research of alcoholic fatty liver disease (AFLD) and retinitis pigmentosa (RP) .

HY-N15637

Torularhodin	Apoptosis	Cancer
Torularhodin is a carotenoid with anti-cancer activity. Torularhodin induces apopotsis of tumor cells and can be used for the study of prostate cancer .

HY-W040206

Diflufenican	Environmental Pollutants Acetolactate Synthase (ALS) Herbicide	Others
Diflufenican is a Herbicide. Diflufenican inhibits phytoene desaturase (PDS) in the carotenoid synthesis pathway. Diflufenican suppresses the production of PDS, blocks carotenoid biosynthesis, thereby inducing chlorophyll destruction and cell membrane rupture, and ultimately causes the death of broadleaf weeds. The combination of Diflufenican and Flufenacet can be used to control Lolium rigidum populations resistant to ALS/ACCase .

HY-N9371

Crocin IV Dicrocin	Endogenous Metabolite	Others
Crocin IV (Dicrocin), a crocetin glycoside, is a carotenoid pigment. Crocin IV has potent antioxidant activity .

HY-W040194

Clomazone	Environmental Pollutants Herbicide	Metabolic Disease
Clomazone is a broad spectrum herbicide, mainly used to control annual broadleaf weeds and grass weeds in various crops such as rice, soybeans, and peanuts. Clomazone inhibits carotenoid biosynthesis, and treated plants show typical "albinism" symptoms due to the destruction of chloroplast membrane structure leading to chlorophyll degradation. Clomazone exhibits multiple toxic effects on non-target organisms, including aquatic lethality, developmental malformations, liver damage, mitochondrial dysfunction, and hematotoxicity .

HY-137910

Tembotrione	Environmental Pollutants HPPD Herbicide	Infection
Tembotrione is a herbicide belonging to the HPPD (dioxygenase) inhibitor class with crop selectivity. Tembotrione effectively controls a variety of weeds including broadleaf and gramineous species by disrupting carotenoid synthesis, which leads to chlorophyll degradation and leaf whitening. Mixing Tembotrione with isoxaflutole or adding surfactants optimizes its efficacy and reduces phytotoxicity, with no residual impact on subsequent cruciferous crops, thus helping to increase maize grain yield. The activity of Tembotrione decreases under drought conditions, and under specific conditions (such as double-dose treatment), it may cause reversible yellowing and even yield reduction in crops such as poppy .

HY-114849

Norflurazon SAN 9789	Environmental Pollutants Herbicide	Others
Norflurazon (SAN 9789) is a bleaching herbicide. Norflurazon can block carotenoid biosynthesis by inhibiting phytoene desaturase activity .

HY-N6884

Bixin 2 Publications Verification	Reactive Oxygen Species (ROS) Apoptosis	Cardiovascular Disease Inflammation/Immunology Cancer
Bixin is an orally active carotenoid found in the seeds of Bixa orellana. Bixin induces apoptosis in cancer cells. Bixin possessing anti-inflammatory, anti-tumor and anti-oxidant activities. Bixin treatment ameliorated cardiac dysfunction through inhibiting fibrosis, inflammation and reactive oxygen species (ROS) generation .

HY-W750676

(rac./meso)-Astaxanthin AstaREAL; AstaXin; BioAstin	Endogenous Metabolite	Metabolic Disease
rac-Astaxanthin is a carotenoid pigment found primarily in marine animals including shrimp and salmon. It is a potent lipid-soluble antioxidant.

HY-N15686

Torulene Torulin	Apoptosis Androgen Receptor Bcl-2 Family MMP	Cancer
Torulene (Torulin) is an orally active carotenoid with anti-cancer activity. Torulene inhibits proliferation and induces apoptosis of tumor cells via a mitochondrial signal pathway and the down-regulation of androgen receptor (AR) expression. Torulene can be used for the study of prostate cancer .

HY-W743654

Capsorubin	Apoptosis	Cancer
Capsorubin is a carotenoid found in peppers with multiple biological activities. Capsorubin (167 μM) inhibits lipid peroxidation induced by 2,2'-azobis(2,4-dimethylvaleronitrile) (AMVN) in vitro. Capsorubin (1 μM) reduces UVB-induced DNA strand breaks and apoptosis in human dermal fibroblasts. Capsorubin also inhibits Epstein-Barr virus early antigen (EBV-EA) activation induced by phorbol 12-myristate 13-acetate in Raji cells, a marker of tumorigenesis.

HY-174423

Iptriazopyrid NC-656	Herbicide	Others
Iptriazopyrid (NC-656) is an azole carboxamide herbicide targeting 4-hydroxyphenylpyruvate dioxygenase (HPPD) with a K_i value of 24.3 nM for Arabidopsis HPPD and 33.3 nM for rice HPPD. Iptriazopyrid blocks plastoquinone and carotenoid synthesis, leading to weed chlorosis and death. Iptriazopyrid is promising for research of controlling weeds such as Echinochloa crus-galli in paddy fields .

HY-N2302R

Fucoxanthin (Standard) all-trans-Fucoxanthin (Standard)	Reference Standards Bacterial PPAR c-Myc NO Synthase Caspase ERK	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Fucoxanthin (Standard) is the analytical standard of Fucoxanthin. This product is intended for research and analytical applications. Fucoxanthin (all-trans-Fucoxanthin) is a marine carotenoid and shows anti-obesity, anti-diabetic, anti-oxidant, anti-inflammatory and anticancer activities .

HY-N9625

Violaxanthin	Photosystem II	Others
Violaxanthin is a lipophilic epoxy carotenoid and a light energy scavenger with biological activities such as antioxidation and anti-inflammation. Violaxanthin exists in photosynthetic eukaryotes including higher plants and participates in the xanthophyll cycle. As a component of the xanthophyll cycle, violaxanthin can be synthesized from zeaxanthin under the catalysis of epoxidase and scavenge excess light energy in photosynthetic eukaryotes .

HY-113326

Phytoene trans-Phytoene	Reactive Oxygen Species (ROS)	Cancer
Phytoene (trans-Phytoene) is a carotene pigment. Phytoene is the precursor of all carotenoids. Phytoene is the predominant PT isomer in most carotenogenic organisms. Phytoene can delay the skin tumors appearance and reduce their number in mice that are induced the tumors with UV-B light. Phytoene leads to protection against oxidative stress and malignant transformation. Phytoene inhibits the proliferation of breast cancer cells .

HY-N7523

Neoxanthin	DNA/RNA Synthesis Apoptosis	Cancer
Neoxanthin is a major xanthophyll carotenoid and a precursor of the plant hormone abscisic acid in dark green leafy vegetables. Neoxanthin is a potent antioxidant and light-harvesting pigment. Neoxanthin induces apoptosis and has anticancer actions .

HY-W750676R

(rac./meso)-Astaxanthin (Standard) AstaREAL (Standard); AstaXin (Standard); BioAstin (Standard)	Endogenous Metabolite Reference Standards	Metabolic Disease
(rac./meso)-Astaxanthin (Standard) is the analytical standard of (rac./meso)-Astaxanthin. This product is intended for research and analytical applications. rac-Astaxanthin is a carotenoid pigment found primarily in marine animals including shrimp and salmon. It is a potent lipid-soluble antioxidant.

HY-W743654R

Capsorubin (Standard)	Apoptosis Reference Standards	Cancer
Capsorubin (Standard) is the analytical standard of Capsorubin. This product is intended for research and analytical applications. Capsorubin is a carotenoid found in peppers with multiple biological activities. Capsorubin (167 μM) inhibits lipid peroxidation induced by 2,2'-azobis(2,4-dimethylvaleronitrile) (AMVN) in vitro. Capsorubin (1 μM) reduces UVB-induced DNA strand breaks and apoptosis in human dermal fibroblasts. Capsorubin also inhibits Epstein-Barr virus early antigen (EBV-EA) activation induced by phorbol 12-myristate 13-acetate in Raji cells, a marker of tumorigenesis.

HY-N0411S4

β-Carotene-13C10 Provitamin A-¹³C₁₀; beta-Carotene-¹³C₁₀	Isotope-Labeled Compounds Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS)	Metabolic Disease Cancer
β-Carotene- ¹³C₁₀ (Provitamin A- ¹³C₁₀) is the ¹³C-labeled β-Carotene (HY-N0411). β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .

HY-N15684

Rhodoxanthin	Others	Metabolic Disease
Rhodoxanthin is a carotenoid. Rhodoxanthin exerts antioxidant activity via free radical scavenging and lipid peroxidation inhibition. Rhodoxanthin is promising for research of oxidative stress-related diseases (e.g., UV-induced skin damage) .

HY-B1960R

Canthaxanthin (Standard) E 161g (Standard); all-trans-Canthaxanthin (Standard)	Reference Standards Reactive Oxygen Species (ROS) Endogenous Metabolite	Inflammation/Immunology Cancer
Canthaxanthin (Standard) is the analytical standard of Canthaxanthin. This product is intended for research and analytical applications. Canthaxanthin is a red-orange carotenoid with various biological activities, such as antioxidant, antitumor properties.

HY-W750678

9-cis-Canthaxanthin	Apoptosis Caspase	Inflammation/Immunology
9-cis-Canthaxanthin is a carotenoid with pro-apoptotic activity in THP-1 macrophage cells. 9-cis-Canthaxanthin induces cell apoptosis by increasing caspase-3 and caspase-8 activity .

HY-N15660

Azafrin	Keap1-Nrf2 Heme Oxygenase (HO)	Cardiovascular Disease Inflammation/Immunology
Azafrin, a carotenoid, is one of the most abundant active ingredients in C. grandiflora. Azafrin increases HO-1, NQO1, and Nrf2 expression. Azafrin shows cardioprotective effect against myocardial injury via activation of the Nrf2-ARE pathway. Azafrin can be used for research of cardiovascular diseases .

HY-W750694

β-Cryptoxanthin palmitate	Drug Derivative	Others
β-Cryptoxanthin palmitate is a carotenoid, and is abundant in peels. Carotenoids are important biological active, and may regulate cellular differentiation, growth control, photooxidative protection, cell membrane stability, photosynthesis, vision process and nutrition .

HY-D1290

Antheraxanthin	Fluorescent Dye	Others
Antheraxanthin, carotenoid, is a photoprotective pigment found in a chromophyte alga .

HY-W750675

Astaxanthin monopalmitate Astaxanthin palmitate	Drug Derivative	Others
Astaxanthin monopalmitate (Astaxanthin palmitate) is an esterified form of Astaxanthin (HY-B2163) (a carotenoid). Astaxanthin monopalmitate degradation resulted in a mixture of free and palmitate apo-astaxanthins. Carotenoids are important biological active, and may regulate cellular differentiation, growth control, photooxidative protection, cell membrane stability, photosynthesis, vision process and nutrition .

HY-W750692

β-Citraurin	Drug Derivative	Others
β-Citraurin is a carotenoid. Jasmonates induce β-Citraurin biosynthesis in citrus by activating a CsMPK6-CsMYC2 cascade, thereby affecting fruit coloration .

HY-N11697

α-Cryptoxanthin	P-glycoprotein	Cancer
α-Cryptoxanthin is a natural carotenoid with anticancer effects. α-Cryptoxanthin inhibits multidrug resistance 1 (MDR1) mediated efflux pump .

HY-W750716

Lutein epoxide Taraxanthin; Lutein 5,6-epoxide	Endogenous Metabolite	Others
Lutein epoxide is a carotenoid. Lutein epoxide can be converted into Lutein (HY-N6947) under the action of light. Lutein epoxide can be used to study the photoprotection mechanism of plants .

HY-N15440

Mutatochrome Citroxanthin	Reactive Oxygen Species (ROS) Endogenous Metabolite	Inflammation/Immunology Cancer
Mutatochrome (Citroxanthin) is a naturally occurring carotenoid pigment found in certain plants. Mutatochrome has antioxidant property to help protect cells from damage caused by free radicals. Mutatochrome can be used for anti-inflammatory and anticancer study .

HY-N10183

Crocin-4	Reactive Oxygen Species (ROS)	Neurological Disease
Crocin-4, a carotenoid constituent of saffron, is a potent and brain-penetrant antioxidant agent. Crocin-4 can inhibit the aggregation and the concomitant deposition of Aβ fibrils in the brain. Crocin-4 can be used for the research of Alzheimer's Disease. Crocin-4 also exhibits antitumor and anti-inflammatory activities .

HY-W740803

15-cis-Phytofluene (15Z)-Phytofluene	Drug Intermediate Drug Isomer	Others
15-cis-Phytofluene is a cis-isomer of Phytofluene. 15-cis-Phytofluene is an acyclic carotenoid. 15-cis-Phytofluene acts as a biosynthetic intermediate in carotenoid biosynthesis .

HY-N15683

3-Hydroxyechinenone	Biochemical Assay Reagents	Others
3-Hydroxyechinenone is a chromophore of the orange carotenoid protein (OCP). 3-Hydroxyechinenone is involved in the photoprotective mechanism of the photosynthetic apparatus of cyanobacteria .

HY-170473

Wheat germ oil	Biochemical Assay Reagents	Others
Wheat germ oil is an oil with nutritional value, especially its high Vitamin E content. Wheat germ oil is rich in health- beneficial bioactive compounds, such as phytosterols, tocopherols, carotenoids, and omega-3 fatty acids .

HY-W750719

Neurosporene	Endogenous Metabolite Drug Intermediate	Cancer
Neurosporene is a carotenoid. Neurosporene is an intermediate in the synthesis of Lycopene (HY-N0287). Neurosporene can be isolated from date palm, Kocuria sp. GMA bacteria, and Anthurus archeri fungi. Neurosporene has antioxidant activity. Neurosporene can be used in the research of diseases such as cancer .

HY-W587784

Norbixin	PPAR	Metabolic Disease
Norbixin is a carotenoid that has been found in B. orellana.It binds to PPARγ in a cell-free assay (Ki = 1.15 μM) . Norbixin attenuates hyperglycemia, hyperinsulinemia, and insulin resistance, as well as decreases serum lipid levels and cardiac levels of thiobarbituric acid reactive substances (TBARS) and glutathione (GSH) in a rat model of cardio-metabolic syndrome .

HY-W719989

γ-Carotene	Drug Intermediate	Metabolic Disease
γ-Carotene is a carotenoid found in Hippophae rhamnoides L. and peach palm fruits. γ-Carotene exhibits no significant inhibitory activity against self-activated hepatic stellate cells in vitro. γ-Carotene can be converted into retinol (Vitamin A) (HY-B1342) and can be used for the research of vitamin A deficiency ^[2].

HY-N6884R

Bixin (Standard)	Reference Standards Reactive Oxygen Species (ROS) Apoptosis	Cardiovascular Disease Inflammation/Immunology Cancer
Bixin (Standard) is the analytical standard of Bixin. This product is intended for research and analytical applications.Bixin is an orally active carotenoid found in the seeds of Bixa orellana. Bixin induces apoptosis in cancer cells. Bixin possessing anti-inflammatory, anti-tumor and anti-oxidant activities. Bixin treatment ameliorated cardiac dysfunction through inhibiting fibrosis, inflammation and reactive oxygen species (ROS) generation.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0287

Lycopene Maximum Cited Publications 19 Publications Verification	Structural Classification Natural Products Classification of Application Fields Endocrine diseases Solanum lycopersicum L. Plants Endogenous metabolite Food Research Infection Human Gut Microbiota Metabolites Immune System Disorder Disease markers Pigments Solanaceae Disease Research Fields Cancer Source Classification	Reactive Oxygen Species (ROS) Endogenous Metabolite
Lycopene is naturally occurring carotenoids found in tomato, tomato products, and in other red fruits and vegetables; exhibits antioxidant effects.

HY-N6947

Lutein 4 Publications Verification Xanthophyll	Animals Classification of Application Fields Terpenoids Whitening Agent Pigments Diterpenoids Cosmetic Research Inflammation/Immunology Disease Research Fields Source Classification Food Research	Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS)
Lutein (Xanthophyll) is a carotenoid with reported anti-inflammatory properties. A large body of evidence shows that lutein has several beneficial effects, especially on eye health . Lutein exerts its biological activities, including anti-inflammation, anti-oxidase and anti-apoptosis, through effects on reactive oxygen species (ROS) . Lutein is able to arrive in the brain and shows antidepressant-like and neuroprotective effects. Lutein is orally active .

HY-B2163

Astaxanthin 15+ Cited Publications	Cardiovascular Disease Classification of Application Fields Anti-aging Whitening Agent Research on Agricultural Breeding Food Research Agricultural Research Microorganisms Sunscreen Terpenoids Pigments Diterpenoids Cosmetic Research Disease Research Fields Source Classification	PPAR Reactive Oxygen Species (ROS) STAT NF-κB Apoptosis
Astaxanthin, the red dietary carotenoid, is an orally effective and potent antioxidant. Astaxanthin inhibits NF-κB and down-regulates VEGF in blood glucose. Astaxanthin exerts anti-cancer cell proliferation, increases apoptosis, impairs migration and invasion by activating PPARγ and reducing the expression of STAT3. Astaxanthin also has neuroprotective and anti-inflammatory activity and can be used in studies of cancer, diabetic retinopathy, cardiovascular disease, and in the coloring of animal feed .

HY-120318

Zeaxanthin 2 Publications Verification	Classification of Application Fields Erythrina melanacantha Taub. ex Harms Whitening Agent Endocrine diseases Plants Compositae Endogenous metabolite Food Research Other Terpenoids Immune System Disorder Microorganisms Terpenoids Disease markers Pigments Cosmetic Research Inflammation/Immunology Disease Research Fields Source Classification	Endogenous Metabolite
Zeaxanthin, a diet-obtained carotenoid, presents in the macula region of the eye. Zeaxanthin shows antioxidant effects .

HY-N2302

Fucoxanthin 10+ Cited Publications all-trans-Fucoxanthin	Natural Products Classification of Application Fields Anti-aging Marine natural products Whitening Agent Metabolic Disease Plants Food Research other families Sunscreen Marine algae Pigments Cosmetic Research Inflammation/Immunology Disease Research Fields Source Classification Cancer	Bacterial PPAR c-Myc NO Synthase Caspase ERK
Fucoxanthin (all-trans-Fucoxanthin) is a marine carotenoid and shows anti-obesity, anti-diabetic, anti-oxidant, anti-inflammatory and anticancer activities .

HY-N0411

β-Carotene 2 Publications Verification Provitamin A; beta-Carotene	Structural Classification Classification of Application Fields Endocrine diseases Metabolic Disease Plants Endogenous metabolite Food Research Other Terpenoids Immune System Disorder other families Terpenoids Disease markers Pigments Disease Research Fields Cancer Source Classification	Environmental Pollutants Endogenous Metabolite Reactive Oxygen Species (ROS) Apoptosis
β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .

HY-B1960

Canthaxanthin 3 Publications Verification E 161g; all-trans-Canthaxanthin	Other Terpenoids Microorganisms Animals Classification of Application Fields Terpenoids Pigments Inflammation/Immunology Disease Research Fields Source Classification Food Research	Reactive Oxygen Species (ROS) Endogenous Metabolite
Canthaxanthin is a red-orange carotenoid with various biological activities, such as antioxidant, antitumor properties.

HY-N6677

β-Apo-8'-carotenal Apocarotenal	Other Terpenoids Structural Classification other families Classification of Application Fields Terpenoids Plants Disease Research Fields Source Classification Cancer	Cytochrome P450 DNA/RNA Synthesis
β-Apo-8'-carotenal (Apocarotenal), an orally active provitamin A carotenoid. β-Apo-8'-carotenal can induce the expression of CYP1A through the Ah receptor-dependent pathway. β-Apo-8'-carotenal can induce cancer cells DNA strand breaks and lipid peroxidation. β-Apo-8'-carotenal can be used for the researches of cancer and metabolic disease .

HY-N0411R

β-Carotene (Standard) Provitamin A (Standard); beta-Carotene (Standard)	Other Terpenoids Structural Classification Immune System Disorder other families Terpenoids Disease markers Endocrine diseases Plants Endogenous metabolite Cancer Source Classification	Reference Standards Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS)
β-Carotene (Standard) is the analytical standard of β-Carotene. This product is intended for research and analytical applications. β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .

HY-N10991

Crocetin dialdehyde	Natural Products Crocus sativus Linn. Iridaceae Plants Source Classification	Drug Derivative
Crocetin dialdehyde is a non-volatile apocarotenoid obtained by the action of the plastidic enzyme CCD2 over the carotenoid zeaxanthin in saffron. Crocetin dialdehyde can be converted into Crocetin (HY-N2072) by aldehyde dehydrogenases (ALDHs). Crocetin dialdehyde has no effect on the liver in mice .

HY-108059

β-Cryptoxanthin (3R)-β-Cryptoxanthin	Other Terpenoids Structural Classification Capsicum annuum L. other families Neurological Disease Classification of Application Fields Terpenoids Solanaceae Plants Endogenous metabolite Disease Research Fields Source Classification	Drug Derivative
β-Cryptoxanthin ((3R)-β-Cryptoxanthin) is an orally active carotenoid found in fruits and vegetables such as angerines, red peppers, and pumpkin. β-Cryptoxanthin inhibits prevents osteoclast formation and inhibits bone resorption. β-Cryptoxanthin maintains retinol status in vivo. β-cryptoxanthin shows anti-inflammation and anticancer activity. β-Cryptoxanthin can be used for the researches of osteoporosis and bladder carcer .

HY-N9182

Zeaxanthin dipalmitate Physalien	Structural Classification Classification of Application Fields Terpenoids Diterpenoids Solanaceae Plants Lycium chinense Miller Inflammation/Immunology Disease Research Fields Source Classification	Adiponectin Receptor P2X Receptor Autophagy
Zeaxanthin dipalmitate (Physalien) is a wolfberry-derived carotenoid, has anti-inflammatory and anti-oxidative stress effects. Zeaxanthin dipalmitate directly interact with p2X7 receptor (K_d=81.2 nM) and adiponectin receptor 1 (AdipoR1; K_d=533 nM) in a positive dose-dependent manner. Zeaxanthin dipalmitate restores mitochondrial autophagy functions suppressed by ethanol intoxication. Zeaxanthin dipalmitate can be used in the research of alcoholic fatty liver disease (AFLD) and retinitis pigmentosa (RP) .

HY-N15637

Torularhodin	Microorganisms Ketones, Aldehydes, Acids Source Classification	Apoptosis
Torularhodin is a carotenoid with anti-cancer activity. Torularhodin induces apopotsis of tumor cells and can be used for the study of prostate cancer .

HY-N9371

Crocin IV Dicrocin	Classification of Application Fields Terpenoids Other Diseases Pigments Diterpenoids Lridaceae Plants Crocus sativus L. Disease Research Fields Food Research Source Classification	Endogenous Metabolite
Crocin IV (Dicrocin), a crocetin glycoside, is a carotenoid pigment. Crocin IV has potent antioxidant activity .

HY-N6884

Bixin 2 Publications Verification	Bixaceae Bixa orellana Linn. Classification of Application Fields Ketones, Aldehydes, Acids Pigments Plants Inflammation/Immunology Disease Research Fields Source Classification Cancer Food Research	Reactive Oxygen Species (ROS) Apoptosis
Bixin is an orally active carotenoid found in the seeds of Bixa orellana. Bixin induces apoptosis in cancer cells. Bixin possessing anti-inflammatory, anti-tumor and anti-oxidant activities. Bixin treatment ameliorated cardiac dysfunction through inhibiting fibrosis, inflammation and reactive oxygen species (ROS) generation .

HY-N15686

Torulene Torulin	Natural Products Microorganisms Source Classification	Apoptosis Androgen Receptor Bcl-2 Family MMP
Torulene (Torulin) is an orally active carotenoid with anti-cancer activity. Torulene inhibits proliferation and induces apoptosis of tumor cells via a mitochondrial signal pathway and the down-regulation of androgen receptor (AR) expression. Torulene can be used for the study of prostate cancer .

HY-N2302R

Fucoxanthin (Standard) all-trans-Fucoxanthin (Standard)	Structural Classification Natural Products other families Marine algae Marine natural products Plants Source Classification	Reference Standards Bacterial PPAR c-Myc NO Synthase Caspase ERK
Fucoxanthin (Standard) is the analytical standard of Fucoxanthin. This product is intended for research and analytical applications. Fucoxanthin (all-trans-Fucoxanthin) is a marine carotenoid and shows anti-obesity, anti-diabetic, anti-oxidant, anti-inflammatory and anticancer activities .

HY-N9625

Violaxanthin	Structural Classification Natural Products Viola tricolor L. Violaceae Plants Source Classification	Photosystem II
Violaxanthin is a lipophilic epoxy carotenoid and a light energy scavenger with biological activities such as antioxidation and anti-inflammation. Violaxanthin exists in photosynthetic eukaryotes including higher plants and participates in the xanthophyll cycle. As a component of the xanthophyll cycle, violaxanthin can be synthesized from zeaxanthin under the catalysis of epoxidase and scavenge excess light energy in photosynthetic eukaryotes .

HY-113326

Phytoene trans-Phytoene	Natural Products Solanum lycopersicum L. Solanaceae Plants Source Classification	Reactive Oxygen Species (ROS)
Phytoene (trans-Phytoene) is a carotene pigment. Phytoene is the precursor of all carotenoids. Phytoene is the predominant PT isomer in most carotenogenic organisms. Phytoene can delay the skin tumors appearance and reduce their number in mice that are induced the tumors with UV-B light. Phytoene leads to protection against oxidative stress and malignant transformation. Phytoene inhibits the proliferation of breast cancer cells .

HY-N7523

Neoxanthin	Natural Products Classification of Application Fields Plants Food Research Agricultural Research Microorganisms other families Pigments Abscisic acid Phytohormone Disease Research Fields Source Classification Cancer	DNA/RNA Synthesis Apoptosis
Neoxanthin is a major xanthophyll carotenoid and a precursor of the plant hormone abscisic acid in dark green leafy vegetables. Neoxanthin is a potent antioxidant and light-harvesting pigment. Neoxanthin induces apoptosis and has anticancer actions .

HY-N15684

Rhodoxanthin	Natural Products Animals Source Classification	Others
Rhodoxanthin is a carotenoid. Rhodoxanthin exerts antioxidant activity via free radical scavenging and lipid peroxidation inhibition. Rhodoxanthin is promising for research of oxidative stress-related diseases (e.g., UV-induced skin damage) .

HY-B1960R

Canthaxanthin (Standard) E 161g (Standard); all-trans-Canthaxanthin (Standard)	Other Terpenoids Structural Classification Microorganisms Animals Terpenoids Source Classification	Reference Standards Reactive Oxygen Species (ROS) Endogenous Metabolite
Canthaxanthin (Standard) is the analytical standard of Canthaxanthin. This product is intended for research and analytical applications. Canthaxanthin is a red-orange carotenoid with various biological activities, such as antioxidant, antitumor properties.

HY-N15660

Azafrin	Ketones, Aldehydes, Acids Centranthera grandiflora Benth. Orobanchaceae Plants Source Classification	Keap1-Nrf2 Heme Oxygenase (HO)
Azafrin, a carotenoid, is one of the most abundant active ingredients in C. grandiflora. Azafrin increases HO-1, NQO1, and Nrf2 expression. Azafrin shows cardioprotective effect against myocardial injury via activation of the Nrf2-ARE pathway. Azafrin can be used for research of cardiovascular diseases .

HY-W750694

β-Cryptoxanthin palmitate	Natural Products Plants Anacardium occidentaleL. Anacardiaceae Source Classification	Drug Derivative
β-Cryptoxanthin palmitate is a carotenoid, and is abundant in peels. Carotenoids are important biological active, and may regulate cellular differentiation, growth control, photooxidative protection, cell membrane stability, photosynthesis, vision process and nutrition .

HY-D1290

Antheraxanthin	Natural Products Microorganisms Source Classification	Fluorescent Dye
Antheraxanthin, carotenoid, is a photoprotective pigment found in a chromophyte alga .

HY-W750692

β-Citraurin	Natural Products Rutaceae Plants Citrus sinensis (L.) Osbeck Source Classification	Drug Derivative
β-Citraurin is a carotenoid. Jasmonates induce β-Citraurin biosynthesis in citrus by activating a CsMPK6-CsMYC2 cascade, thereby affecting fruit coloration .

HY-N11697

α-Cryptoxanthin	Natural Products Capsicum annuum L. Solanaceae Plants Source Classification	P-glycoprotein
α-Cryptoxanthin is a natural carotenoid with anticancer effects. α-Cryptoxanthin inhibits multidrug resistance 1 (MDR1) mediated efflux pump .

HY-W750716

Lutein epoxide Taraxanthin; Lutein 5,6-epoxide	Other Terpenoids Structural Classification Terpenoids Biancaea decapetala (Roth) O. Deg. Plants Compositae Source Classification	Endogenous Metabolite
Lutein epoxide is a carotenoid. Lutein epoxide can be converted into Lutein (HY-N6947) under the action of light. Lutein epoxide can be used to study the photoprotection mechanism of plants .

HY-N15440

Mutatochrome Citroxanthin	Natural Products Rosaceae Plants Rosa foetida Herrm. Source Classification	Reactive Oxygen Species (ROS) Endogenous Metabolite
Mutatochrome (Citroxanthin) is a naturally occurring carotenoid pigment found in certain plants. Mutatochrome has antioxidant property to help protect cells from damage caused by free radicals. Mutatochrome can be used for anti-inflammatory and anticancer study .

HY-N10183

Crocin-4	Crocus sativus Linn. Iridaceae Terpenoids Diterpenoids Plants Source Classification	Reactive Oxygen Species (ROS)
Crocin-4, a carotenoid constituent of saffron, is a potent and brain-penetrant antioxidant agent. Crocin-4 can inhibit the aggregation and the concomitant deposition of Aβ fibrils in the brain. Crocin-4 can be used for the research of Alzheimer's Disease. Crocin-4 also exhibits antitumor and anti-inflammatory activities .

HY-W740803

15-cis-Phytofluene (15Z)-Phytofluene	Natural Products Rosaceae Plants Prunus armeniaca L. Source Classification	Drug Intermediate Drug Isomer
15-cis-Phytofluene is a cis-isomer of Phytofluene. 15-cis-Phytofluene is an acyclic carotenoid. 15-cis-Phytofluene acts as a biosynthetic intermediate in carotenoid biosynthesis .

HY-N15683

3-Hydroxyechinenone	Natural Products Microorganisms Source Classification	Biochemical Assay Reagents
3-Hydroxyechinenone is a chromophore of the orange carotenoid protein (OCP). 3-Hydroxyechinenone is involved in the photoprotective mechanism of the photosynthetic apparatus of cyanobacteria .

HY-W750719

Neurosporene	Natural Products Microorganisms Source Classification	Endogenous Metabolite Drug Intermediate
Neurosporene is a carotenoid. Neurosporene is an intermediate in the synthesis of Lycopene (HY-N0287). Neurosporene can be isolated from date palm, Kocuria sp. GMA bacteria, and Anthurus archeri fungi. Neurosporene has antioxidant activity. Neurosporene can be used in the research of diseases such as cancer .

HY-W587784

Norbixin	Bixaceae Bixa orellana Linn. Ketones, Aldehydes, Acids Plants Source Classification	PPAR
Norbixin is a carotenoid that has been found in B. orellana.It binds to PPARγ in a cell-free assay (Ki = 1.15 μM) . Norbixin attenuates hyperglycemia, hyperinsulinemia, and insulin resistance, as well as decreases serum lipid levels and cardiac levels of thiobarbituric acid reactive substances (TBARS) and glutathione (GSH) in a rat model of cardio-metabolic syndrome .

HY-W719989

γ-Carotene	Structural Classification Natural Products Elaeagnaceae Hippophaë rhamnoides Plants Source Classification	Drug Intermediate
γ-Carotene is a carotenoid found in Hippophae rhamnoides L. and peach palm fruits. γ-Carotene exhibits no significant inhibitory activity against self-activated hepatic stellate cells in vitro. γ-Carotene can be converted into retinol (Vitamin A) (HY-B1342) and can be used for the research of vitamin A deficiency ^[2].

HY-N6884R

Bixin (Standard)	Bixaceae Bixa orellana Linn. Ketones, Aldehydes, Acids Plants Source Classification	Reference Standards Reactive Oxygen Species (ROS) Apoptosis
Bixin (Standard) is the analytical standard of Bixin. This product is intended for research and analytical applications.Bixin is an orally active carotenoid found in the seeds of Bixa orellana. Bixin induces apoptosis in cancer cells. Bixin possessing anti-inflammatory, anti-tumor and anti-oxidant activities. Bixin treatment ameliorated cardiac dysfunction through inhibiting fibrosis, inflammation and reactive oxygen species (ROS) generation.

HY-W750691

Citranaxanthin	Natural Products Marine natural products Other marine organisms Source Classification	Drug Derivative
Citranaxanthin is a carotenoid that can be isolated from Sea Hare Dolabella auriculari. Carotenoids are important biological active, and may regulate cellular differentiation, growth control, photooxidative protection, cell membrane stability, photosynthesis, vision process and nutrition .

HY-W719977

Astacene	Natural Products Animals Source Classification	Drug Derivative
Astacene is a major secondary carotenoid that can be extracted from the skin of the goldfish and other species. Astacene is an oxidative artifact of Astaxanthin (HY-B2163). Carotenoids are important biological active, and may regulate cellular differentiation, growth control, photooxidative protection, cell membrane stability, photosynthesis, vision process and nutrition .

HY-W782321

β-Apo-12'-carotenal 12'-Apo-β-carotenal	Other Terpenoids Structural Classification Capsicum annuum L. Terpenoids Solanaceae Plants Source Classification	Drug Derivative
β-Apo-12'-carotenal (12'-Apo-β-carotenal) is a carotenoid derivative. β-Apo-12'-carotenal can be isolated from chili pepper fruits. Carotenoids are important biological active, and may regulate cellular differentiation, growth control, photooxidative protection, cell membrane stability, photosynthesis, vision process and nutrition .

HY-W720006

4,4'-Diapo-ω,ω-carotene-4,4'-dial	Natural Products Araucariaceae Plants Araucaria cunninghamii Mudie Source Classification	Drug Derivative
4,4'-Diapo-ω,ω-carotene-4,4'-dial is a carotenoid pigment. Carotenoids are important biological active, and may regulate cellular differentiation, growth control, photooxidative protection, cell membrane stability, photosynthesis, vision process and nutrition .

HY-W782495

Cucurbitaxanthin A Capsolutein	Natural Products Capsicum annuum L. Solanaceae Plants Source Classification	Drug Derivative
Cucurbitaxanthin A (Capsolutein) is a peculiar carotenoid containing an 3,6-oxabicycloheptane end group. Cucurbitaxanthin A is a carotenoid pigment .

HY-N15680

Anhydrolutein II	Natural Products Polygonaceae Rumex rugosus Campd. Plants Source Classification	Drug Derivative
Anhydrolutein II, a carotenoid, is a dehydration product of Lutein (HY-N6947) .

HY-W750707

4-Hydroxyechinenone	Natural Products Animals Source Classification	Drug Metabolite
4-Hydroxyechinenone is a trace carotenoid present in the carapaces of crabs. 4-Hydroxyechinenone is also an intermediate in the metabolism of β-Carotene (HY-N0411) to Astaxanthin (HY-B2163) .

HY-W750700

Dihydroxylycopene 1,1'-Dihydroxylycopene	Natural Products Microorganisms Source Classification	Endogenous Metabolite
Dihydroxylycopene is a polar carotenoid that is essential for photosynthesis in phototrophic bacteria. Dihydroxylycopene is an essential carotenoid in Phaeospirillum .

HY-N12698

(9Z)-Antheraxanthin	Natural Products Microorganisms Source Classification	Others
(9Z)-Antheraxanthin is a carotenoid and can be isolated from K. antarctica .

HY-124385

Tunaxanthin	Structural Classification Natural Products Solanum lycopersicum L. Solanaceae Plants Source Classification	Biochemical Assay Reagents
Tunaxanthin is a xanthophyll, exists in fruits of various tomato strains and their hybrid. Tunaxanthin is also a carotenoid present in fish .

HY-W750709

Isozeaxanthin	Other Terpenoids Structural Classification Animals Terpenoids Source Classification	Endogenous Metabolite
Isozeaxanthin is a carotenoid that can be isolated from some Antarctic fish (e.g. species from the families Rajidae and Notothenidae) .

HY-W750708

Idoxanthin	Natural Products Animals Source Classification	Drug Metabolite
Idoxanthin is a metabolite of Astaxanthin (HY-B2163). Idoxanthin is involved in the metabolic pathway of Carotenoids, and its formation and accumulation reflect the metabolic capacity and metabolic pathways of different fish species .

HY-N9371R

Crocin IV (Standard) Dicrocin (Standard)	Structural Classification Terpenoids Diterpenoids Lridaceae Plants Crocus sativus L. Source Classification	Reference Standards Endogenous Metabolite
Crocin IV (Standard) is the analytical standard of Crocin IV. This product is intended for research and analytical applications. Crocin IV (Dicrocin), a crocetin glycoside, is a carotenoid pigment. Crocin IV has potent antioxidant activity .

HY-W595136

(rac)-α-Carotene	Natural Products Leguminosae Ulex europaeus L. Plants Source Classification	Endogenous Metabolite
(rac)-α-Carotene is the racemate of α-Carotene. α-Carotene is a carotenoid and potent antioxidant. Serum α-Carotene concentrations are inversely associated with the risk of all-cause mortality, cardiovascular disease, cancer, and mortality from all causes other than cardiovascular disease and cancer .

Cat. No.	Product Name	Chemical Structure

HY-N0411S4

β-Carotene-13C10

β-Carotene- ¹³C₁₀ (Provitamin A- ¹³C₁₀) is the ¹³C-labeled β-Carotene (HY-N0411). β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .

HY-W778236

Norflurazon-13C,d3
Norflurazon- ¹³C,d₃ (SAN 9789- ¹³C,d₃) is the deuterium and ¹³C-labeled Norflurazon (HY-114849). Norflurazon (SAN 9789) is a bleaching herbicide. Norflurazon can block carotenoid biosynthesis by inhibiting phytoene desaturase activity .

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