1. Cell Cycle/DNA Damage
    Apoptosis
  2. DNA/RNA Synthesis
    Apoptosis
  3. Neoxanthin

Neoxanthin 

Cat. No.: HY-N7523
Handling Instructions

Neoxanthin is a major xanthophyll carotenoid and a precursor of the plant hormone abscisic acid in dark green leafy vegetables. Neoxanthin is a potent antioxidant and light-harvesting pigment. Neoxanthin induces apoptosis and has anticancer actions.

For research use only. We do not sell to patients.

Neoxanthin Chemical Structure

Neoxanthin Chemical Structure

CAS No. : 14660-91-4

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Description

Neoxanthin is a major xanthophyll carotenoid and a precursor of the plant hormone abscisic acid in dark green leafy vegetables. Neoxanthin is a potent antioxidant and light-harvesting pigment. Neoxanthin induces apoptosis and has anticancer actions[1][2].

In Vitro

Neoxanthin (20 μM; 72 h) treatment significantly reduces cell viability to 10.9% for PC-3 cells, 15.0% for DU 145 cells, and nearly zero for LNCaP cells, respectively[1].
Neoxanthin strongly inhibits cell growth by suppressing DNA synthesis in C3H10T1/2 cells[1].
In photosynthetic organisms, Neoxanthin is the essential component of both the photosystem I (PSI) and photosystem II (PSII) reaction centers of oxygenic photosynthetic apparatus[2].

In Vivo

The gastrointestinal metabolism of Neoxanthin in mice is investigated. Two hours after the oral administration of Neoxanthin (40 nmol/mouse), Neoxanthin is found in the plasma and livers of mice. The concentrations of Neoxanthin is 13.6-9.0 nM in plasma, and 7.3 3.6 pmol/g in liver, respectively. (R/S)-Neochrome is also found in the small intestinal contents of Neoxanthin-administered mice[3].

Molecular Weight

600.87

Formula

C₄₀H₅₆O₄

CAS No.

14660-91-4

SMILES

CC(/C=C/[[email protected]](O1)(C(C)(C2)C)[[email protected]]1(C[[email protected]]2O)C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=[[email protected]@]=C([[email protected]](O)(C3)C)C(C)(C[[email protected]@H]3O)C

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

NeoxanthinDNA/RNA SynthesisApoptosisAntioxidantanticancerlight-harvestingpigmentphotosystemxanthophyllcarotenoidDNAantiproliferativeInhibitorinhibitorinhibit

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