Torularhodin
Torularhodin is a carotenoid with anti-cancer activity. Torularhodin induces apopotsis of tumor cells and can be used for the study of prostate cancer.
For research use only. We do not sell to patients.
- CAS No.: 514-92-1
- Formula: C40H52O2
- Molecular Weight:564.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Four to six-week-old BALB/c nude mice (male, 18-22 g) were subcutaneously injected with PC-3 cells (5 × 105 cells)[1]
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Dosage:9 mg/kg, 18 mg/kg
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Administration:p.o; every day; 2 weeks before transplantation; 7 weeks after transplantation
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Result:Lowered the mean number of tumors.
Tumor degeneration, apoptosis and necrosis presented at the end of the experiment.
Increased the mRNA expressions of caspase-3, 8 and 9 in tumor tissues.
Showed Bcl-2 expression of the control group was higher than that of the carotenoid-treated group while the expression of Bax was lower than the carotenoid-treated group.
Chemical Information
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CAS No. 514-92-1
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Molecular Weight 564.84
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Formula C40H52O2
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SMILES
OC(/C(C)=C/C=C/C(C)=C/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)=O
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Structure Classification
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Initial Source
Rhodotorula rubra
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Torularhodin Related Classifications
HY-N15637 Related Classifications
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