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Cat. No.: HY-N17468

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Neocrocin B

Neocrocin B is a carotenoid crocin. Neocrocin B inhibits L-Glutamic acid (HY-14608)-induced neuronal cell damage in a dose-dependent manner. Neocrocin B can be used in studies related to neuronal injury.

For research use only. We do not sell to patients.

CAS No.: 2001062-74-2
Formula: C₄₈H₆₀O₂₂
Molecular Weight:988.98

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Neocrocin B Chemical Structure

CAS No.: 2001062-74-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Neocrocin B (0.1-10 μM; 24 h) exhibits minimal neuroprotective activity against H₂O₂-induced injury in SH-SY5Y human neuroblastoma cells, with a maximum protection rate of 10.39 ± 4.85 at 10 μM^[1].
Neocrocin B (0.1-10 μM; 24 h) exhibits dose-dependent neuroprotective activity against L-glutamic acid-induced injury in SH-SY5Y human neuroblastoma cells, with a maximum protection rate of 40.03 ± 3.91 at 10 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2001062-74-2
Molecular Weight 988.98
Formula C₄₈H₆₀O₂₂
SMILES

OC(C=C1/C=C/C(O[C@H]2[C@@H]([C@@H](C[C@](O)(C2)C(O)=O)O)OC(/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C(O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)=O)=O)=O)=C(C=C1)O
Structure Classification
- Saccharides
- Polysaccharides
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ni Y, et al. Discovery and LC-MS Characterization of New Crocins in Gardeniae Fructus and Their Neuroprotective Potential. J Agric Food Chem. 2017;65(14):2936-2946. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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