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Results for "

GA

" in MedChemExpress (MCE) Product Catalog:

54

Inhibitors & Agonists

3

Fluorescent Dye

2

Biochemical Assay Reagents

15

Peptides

1

Inhibitory Antibodies

3

Natural
Products

12

Recombinant Proteins

1

Isotope-Labeled Compounds

4

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-147082

    YAP Cancer
    GA-017 is a potent and selective LATS1 and LATS2 (large tumor suppressor kinase 1/2) inhibitor, with IC50 values of 4.10 and 3.92 nM, respectively. GA-017 is an activator of cell proliferation. GA-017 promotes YAP/TAZ activation and nuclear translocation. GA-017 promotes cell growth under 3D culture conditions. GA-017 enhances the ex vivo formation of mouse intestinal organoids .
    <em>GA</em>-017
  • HY-126558

    Others Others
    GA3-AM is a cell permeable analog of the plant hormone gibberellic acid that acts as a chemical dimerizer or chemical inducer of dimerization .
    <em>GA</em>3-AM
  • HY-136476D

    Bacterial Infection
    Ga(III)protoporphyrin-IX is a model for the key interporphyrin interactions in malaria pigment. Ga(III)protoporphyrin-IX acts as a potent antibacterial against gram-negative, gram-positive, and acid-fast bacteria. Ga(III)protoporphyrin-IX is readily soluble in methanol (MeOH). Ga(III)protoporphyrin IX are as malarial pigment analogues for agent development and as potential antibacterial agents .
    <em>Ga</em>(III) protoporphyrin IX
  • HY-145853

    Bacterial Infection Inflammation/Immunology
    GA-O-02, a 18β-Glycyrrhetinic acid derivative, is a potent antimicrobial and anti-inflammatory agent. GA-O-02 exerts anti-inflammation through the inhibition of NO, pro-inflammatory cytokines and chemokines. GA-O-02 displays a high antimicrobial activity against Gram-positive bacteria .
    <em>GA</em>-O-02
  • HY-145854

    Bacterial Infection Inflammation/Immunology
    GA-O-06, a 18β-Glycyrrhetinic acid derivative, is a potent antimicrobial and anti-inflammatory agent. GA-O-06 exerts anti-inflammation through the inhibition of NO, pro-inflammatory cytokines and chemokines. GA-O-06 displays a high antimicrobial activity against Gram-positive bacteria .
    <em>GA</em>-O-06
  • HY-163340

    Glucocorticoid Receptor Androgen Receptor Cancer
    GA32 (compound 58r) is potent androgen receptor (AR)/glucocorticoid receptor (GR) dual inhibitor with IC50 values of 0.13 μM and 0.83 μM for AR and GR, respectively. GA32 inhibits the proliferation of Enzalutamide (HY-70002) resistance castration-resistant prostate cancer both in vitro and in vivo .
    <em>GA</em>32
  • HY-D1289

    Fluorescent Dye Others
    GA-PEG5-bromide is a probe used for molecular labeling.
    <em>GA</em>-PEG5-bromide
  • HY-125572

    GA7

    Others Others
    Gibberellin A7 (GA7) is a plant hormone. Gibberellin A7 is the metabolite of Gibberella fujikuroi. Gibberellin A7 promotes the plant growth and elongation of cells .
    Gibberellin A7
  • HY-N11643

    GA-Mk

    Apoptosis Reactive Oxygen Species MMP Caspase Cancer
    Ganoderic acid Mk (GA-Mk) is a triterpenoid acid, that can be isolated from the mycelia of Ganoderma lucidum. Ganoderic acid Mk is efficiently anti-proliferative and can induce apoptosis of HeLa cells by mitochondria-mediated pathway. Ganoderic acid Mk can be used for cervical cancer research .
    Ganoderic acid Mk
  • HY-P9910

    GA101; Anti-Human CD20 type II, Humanized Antibody

    CD20 Cancer
    Obinutuzumab (GA101) a novel glycoengineered Type II CD20 humanized IgG1 monoclonal antibody in development for non-Hodgkin lymphoma.
    Obinutuzumab
  • HY-N11645

    GA-Mf

    Apoptosis Cancer
    Ganoderic acid Mf is an antitumor triterpenoid. Ganoderic acid Mf causes cell cycle arrest in the G1 phase. Ganoderic acid Mf shows high selectivity between normal and cancer cells and induces cell apoptosis via mitochondria mediated pathway .
    Ganoderic acid Mf
  • HY-102007

    HSP Cancer
    Gamitrinib TPP is a Gamitrinib (GA) mitochondrial matrix inhibitor. Gamitrinib TPP is a mitochondrial targeted HSP90 inhibitor with anti-cancer activity.
    Gamitrinib TPP
  • HY-102007A

    HSP Cancer
    Gamitrinib TPP hexafluorophosphate is a Gamitrinib (GA) mitochondrial matrix inhibitor. Gamitrinib TPP hexafluorophosphate is a mitochondrial targeted HSP90 inhibitor with anti-cancer activity.
    Gamitrinib TPP hexafluorophosphate
  • HY-D2297

    Fluorescent Dye Others
    AIE-GA is a Golgi apparatus (GA) fluorescent probe (green channel: λex = 405 nm, λem = 500-700 nm). AIE-GA has a favourable binding ability to interact with COX-2. AIE-GA binds to the cyclooxygenase catalytic site of COX-2 .
    AIE-<em>GA</em>
  • HY-128873

    ADC Cytotoxin DNA Alkylator/Crosslinker Cancer
    Duocarmycin GA is an antibody agent conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin GA can be used against multi-agent resistant cell lines.
    Duocarmycin <em>GA</em>
  • HY-157977

    Biochemical Assay Reagents Others
    DOTA-GA-maleimide is a macrocyclic chelator, which forms stable complex with metals. DOTA-GA-maleimide is utilized as radiolabelled imaging agent .
    DOTA-<em>GA</em>-maleimide
  • HY-136312

    HSP Cancer
    17-DMAP-GA, a Geldanamycin (HY-15230) analogue, is an inhibitor of HSP90. 17-DMAP-GA causes cell cycle abnormalities .
    17-DMAP-<em>GA</em>
  • HY-150240

    Liposome Cancer
    DOPE-GA can be used for formulation of liposome, and used in the research of drug delivery .
    DOPE-<em>GA</em>
  • HY-130997

    ADC Cytotoxin HSP Infection Cancer
    17-GMB-APA-GA is an ADC Cytotoxin. 17-GMB-APA-GA is a potent HSP90 inhibitor and used for latent T. gondii infection research .
    17-GMB-APA-<em>GA</em>
  • HY-W614269

    Others Others
    DOTA-GA(tBu)4 is a macrocyclic chelator used in medical imaging .
    DOTA-<em>GA</em>(tBu)4
  • HY-133570

    HSP ADC Cytotoxin Cancer
    17-AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion. ADCs Toxin .
    17-AEP-<em>GA</em>
  • HY-156829

    Others Cancer
    PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 1:1) is a matrix materia, with lactic acid (LA):glycolic acid (GA) = 1:1, that acts as anti-cancer drug delivery. PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 1:1) can improve a drug's bioavailability, efficacy, water solubility, drug encapsulation efficiency, sustained drug release, and to minimize undesirable toxicity .
    PLGA-PEG-PLGA (1500-1500-1500) (LA/<em>GA</em> 1:1)
  • HY-156829A

    Others Cancer
    PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1) is a matrix materia, with lactic acid (LA):glycolic acid (GA) = 15:1, that acts as anti-cancer drug delivery. PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1) can improve a drug's bioavailability, efficacy, water solubility, drug encapsulation efficiency, sustained drug release, and to minimize undesirable toxicity .
    PLGA-PEG-PLGA (1500-1500-1500) (LA/<em>GA</em> 15:1)
  • HY-148776

    Biochemical Assay Reagents Others
    PLGA-PEG-MAL (20kDA-5.0kDA, LA:GA ratio 50:50) is a kind of poly(lactide-co-glycolide)-block-poly(ethylene glycol) (PLGA-PEG-Mal) nanoparticles. PLGA-PEG-MAL (20kDA-5.0kDA, LA:GA ratio 50:50) has a molecular weight of 20kDA to 5.0kDA and contains a 50:50 ratio of lactic acid (LA) to glycolic acid (GA) molecules. The molecular ratio of LA to GA determines the rate of matrix degradation and protein re-release .
    PLGA-PEG-MAL (20kDA-5.0kDA, LA:<em>GA</em> ratio 50:50)
  • HY-148775

    Biochemical Assay Reagents Others
    PLGA-PEG-MAL (60kDA-3.4kDA, LA:GA ratio 75:25) is a kind of poly(lactide-co-glycolide)-block-poly(ethylene glycol) (PLGA-PEG-Mal) nanoparticles. PLGA-PEG-MAL (60kDA-3.4kDA, LA:GA ratio 75:25) has a molecular weight of 60kDA to 3.4kDA and contains a 75:25 ratio of lactic acid (LA) to glycolic acid (GA) molecules .
    PLGA-PEG-MAL (60kDA-3.4kDA, LA:<em>GA</em> ratio 75:25)
  • HY-148775B

    Biochemical Assay Reagents Others
    PLGA-PEG-MAL (20kDA-5.0kDA, LA:GA ratio 40:60) is a kind of poly(lactide-co-glycolide)-block-poly(ethylene glycol) (PLGA-PEG-Mal) nanoparticles. PLGA-PEG-MAL (20kDA-5.0kDA, LA:GA ratio 40:60) has a molecular weight of 60kDA to 3.4kDA and contains a 75:25 ratio of lactic acid (LA) to glycolic acid (GA) molecules .
    PLGA-PEG-MAL (20kDA-5.0kDA, LA:<em>GA</em> ratio 40:60)
  • HY-148682

    Glycyrrhetic acid 3-O-hydrogen sulfate

    11β-HSD Drug Metabolite Metabolic Disease Inflammation/Immunology
    18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)) is a potent type 2 11β-hydroxysteroid dehydrogenase (11β-HSD2) inhibitor with an IC50 of 0.10 µM using rat kidney microsome. 18β-Glycyrrhetyl-3-O-sulfate is the major metabolite of Glycyrrhetinic acid (GA). 18β-Glycyrrhetyl-3-O-sulfate is the substrate of organic anion transporter (OAT) 1 and OAT3. 18β-Glycyrrhetyl-3-O-sulfate has anti-inflammatory effects and has the potential for pseudohyperaldosteronism research .
    18β-Glycyrrhetyl-3-O-sulfate
  • HY-B1886

    Others Others
    Chlorocholine chloride is an effective plant growth regulator. Chlorocholine chloride can inhibit gibberellin (GA) biosynthesis. Chlorocholine chloride can be used for the research of the mechanisms and effects of GA on plant cell growth and differentiation .
    Chlorocholine chloride
  • HY-N2011

    n-Octyl GAllate; Stabilizer GA 8

    Octyl gallate (Progallin O) is widely used as a food additive, with antimicrobial and antioxidant activity . Octyl gallate (Progallin O) shows selective and sensitive fluorescent property . Octyl gallate shows a marked antiviral effect against HSV-1, vesicular stomatitis virus (VSV) and poliovirus .
    Octyl gallate
  • HY-P5362

    Somatostatin Receptor Cancer
    NODAGA-LM3 can be labeled by 68Ga for PET imaging. 68Ga-NODAGA-LM3 is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas .
    NODAGA-LM3
  • HY-P5362A

    Somatostatin Receptor Cancer
    NODAGA-LM3 TFA can be labeled by 68Ga for PET imaging. 68Ga-NODAGA-LM3 TFA is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas .
    NODAGA-LM3 TFA
  • HY-B1886S1

    Isotope-Labeled Compounds Others
    Chlorocholine-d9 (chloride) is the deuterium labeled Chlorocholine chloride[1]. Chlorocholine chloride is an effective plant growth regulator. Chlorocholine chloride can inhibit gibberellin (GA) biosynthesis. Chlorocholine chloride can be used for the research of the mechanisms and effects of GA on plant cell growth and differentiation[2][3].
    Chlorocholine-d9 chloride
  • HY-125979

    Others Others
    TSPC is a phytohormone gibberellin (GA) perception inhibitor with an IC50 value of 10 μM in vitro .
    TSPC
  • HY-129042
    Cibacron Blue 3G-A
    1 Publications Verification

    Fluorescent Dye Beta-lactamase Infection
    Cibacron Blue 3G-A is an anthraquinone dye, inhibits the R46 β-lactamase with a Ki value of 1.2 uM .
    Cibacron Blue 3G-A
  • HY-153549

    CXCR Others
    Pentixafor is a peptide that targets CXCR4. Pentixafor is capable of being labelled with 68Gallium ( 68Ga) for positron emission tomography (PET) imaging .
    Pentixafor
  • HY-P0271

    CaMK Autophagy Neurological Disease
    Syntide 2, a Ca 2+- and calmodulin (CaM)-dependent protein kinase II (CaMKII) substrate peptide, selectively inhibits the gibberellin (GA) response, leaving constitutive and abscisic acid-regulated events unaffected .
    Syntide 2
  • HY-P0271A
    Syntide 2 TFA
    1 Publications Verification

    CaMK Neurological Disease
    Syntide 2 (TFA), a Ca 2+- and calmodulin (CaM)-dependent protein kinase II (CaMKII) substrate peptide, selectively inhibits the gibberellin (GA) response, leaving constitutive and abscisic acid-regulated events unaffected .
    Syntide 2 TFA
  • HY-146180

    FAP Cancer
    FSDD0I is an albumin-binding fibroblast activation protein (FAP) ligand. FSDD0I can be labeled with 68Ga and 177Lu for single photon emission computed tomography (SPECT) imaging .
    FSDD0I
  • HY-146181

    FAP Cancer
    FSDD1I is an albumin-binding fibroblast activation protein (FAP) ligand. FSDD1I can be labeled with 68Ga and 177Lu for single photon emission computed tomography (SPECT) imaging .
    FSDD1I
  • HY-146182

    FAP Cancer
    FSDD3I is an albumin-binding fibroblast activation protein (FAP) ligand. FSDD3I can be labeled with 68Ga and 177Lu for single photon emission computed tomography (SPECT) imaging .
    FSDD3I
  • HY-P3853

    Neurokinin Receptor Neurological Disease
    GR 87389 is a potent NK2 receptor antagonist. GR 87389 antagonized GA 64349-induced smooth muscle strips contractions in a competitive manner in the human detrusor, prostate and prostatic urethra .
    GR 87389
  • HY-P5128

    Satoreotide tetraxetan

    Somatostatin Receptor Cancer
    DOTA-JR11 is a somatostatin receptor 2 (SSTR2)antagonist. DOTA-JR11 can be labeled by 68Ga, used for paired imaging in neuroendocrine tumors (NETs) research .
    DOTA-JR11
  • HY-148370A

    RG6299 sodium

    Complement System Others
    IONIS-FB-LRx sodium is a specific antisense oligonucleotide (ASO) targeting complement factor B (CFB). IONIS-FB-LRx sodium effectively reduces circulating levels of CFB, and can be used for geographic atrophy (GA) research .
    IONIS-FB-LRx sodium
  • HY-148370

    RG6299

    Complement System Others
    IONIS-FB-LRx is a specific antisense oligonucleotide (ASO) targeting complement factor B (CFB). IONIS-FB-LRx effectively reduces circulating levels of CFB. IONIS-FB-LRx can be used for geographic atrophy (GA) research .
    IONIS-FB-LRx
  • HY-128775

    Others Cancer
    JHU395 is an orally-bioavailable and a plasma stable lipophilic glutamine antagonists (GA) proagent. JHU395 delivers 6-diazo-5-oxo-L-norleucine (DON) to malignant peripheral nerve sheath tumor (MPNST) in vitro and in vivo, and has antitumor activity in MPNST .
    JHU395
  • HY-148457

    Complement System Infection Inflammation/Immunology
    Avacincaptad pegol, which is a pegylated aptamer, has garnered significant attention as a C5 complement inhibitor that may reduce inflammation-related retinal pigment epithelium (RPE) damage. Avacincaptad pegol caqn be used for the research of stargardt macular dystrophy (STGD1) and geographic atrophy (GA) .
    Avacincaptad pegol
  • HY-128642

    FAP Cancer
    FAPI-2 is a quinoline-based therapeutic ligand targeting fibroblast activator protein. FAPI-2, a ligand for the synthesis of 68Ga-FAPI-2, is a PET tracer. FAPI-2 is a fibroblast activating protein (FAP) inhibitor that can be used in cancer research .
    FAPI-2
  • HY-D1536

    Fluorescent Dye Neurological Disease
    Glycine cresol red is a complexometric indicator. Glycine cresol red forms coloured complexes with Al 3+, Ga 3+ and In 3+ ions in aqueous solutions. Glycine cresol red can been used for the spectrophotometric determination of inorganic ions. Glycine cresol red can be used as a stain in neurohistology .
    Glycine cresol red
  • HY-128643
    FAPI-4
    Maximum Cited Publications
    20 Publications Verification

    FAP Cancer
    FAPI-4 is a potent fibroblast activation protein (FAP) inhibitor for the targeting FAP. FAPI-4 can be used in cancer research. 68Ga-FAPI-4 PET/CT is a promising new diagnostic method for imaging various kinds of cancer, with good tumor-to-background contrast ratios .
    FAPI-4
  • HY-P5126

    Somatostatin Receptor Cancer
    DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 and 68 Ga-DOTA-LM3. 68 Ga-DOTA-LM3 shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis .
    DOTA-LM3

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