DOTA-GA-maleimide

Cat. No.: HY-157977: FAQs
Data Sheet Handling Instructions

Molarity Calculator

DOTA-GA-maleimide is a macrocyclic chelator, which forms stable complex with metals. DOTA-GA-maleimide is utilized as radiolabelled imaging agent.

For research use only. We do not sell to patients.

DOTA-GA-maleimide Chemical Structure

CAS No. : 1800229-46-2

Size	Price	Stock	Quantity
5 mg	USD 140	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 220	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 425	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 680	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 1060	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Purity & Documentation
References
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Description

DOTA-GA-maleimide is a macrocyclic chelator, which forms stable complex with metals. DOTA-GA-maleimide is utilized as radiolabelled imaging agent^[1].

Molecular Weight

598.60

Formula

C₂₅H₃₈N₆O₁₁

CAS No.

1800229-46-2

Appearance

Solid

SMILES

O=C(CN1CCN(CCN(C(CCC(NCCN2C(C=CC2=O)=O)=O)C(O)=O)CCN(CC1)CC(O)=O)CC(O)=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

H₂O : 250 mg/mL (417.64 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6706 mL	8.3528 mL	16.7056 mL
5 mM	0.3341 mL	1.6706 mL	3.3411 mL
10 mM	0.1671 mL	0.8353 mL	1.6706 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Xavier ME, et al., Pre-labelling versus direct labelling of anthrax proteins for imaging of matrix metalloproteinases activity using DOTA-GA. Nucl Med Biol. 2019 May-Jun;72-73:49-54. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.6706 mL	8.3528 mL	16.7056 mL	41.7641 mL
	5 mM	0.3341 mL	1.6706 mL	3.3411 mL	8.3528 mL
	10 mM	0.1671 mL	0.8353 mL	1.6706 mL	4.1764 mL
	15 mM	0.1114 mL	0.5569 mL	1.1137 mL	2.7843 mL
	20 mM	0.0835 mL	0.4176 mL	0.8353 mL	2.0882 mL
	25 mM	0.0668 mL	0.3341 mL	0.6682 mL	1.6706 mL
	30 mM	0.0557 mL	0.2784 mL	0.5569 mL	1.3921 mL
	40 mM	0.0418 mL	0.2088 mL	0.4176 mL	1.0441 mL
	50 mM	0.0334 mL	0.1671 mL	0.3341 mL	0.8353 mL
	60 mM	0.0278 mL	0.1392 mL	0.2784 mL	0.6961 mL
	80 mM	0.0209 mL	0.1044 mL	0.2088 mL	0.5221 mL
	100 mM	0.0167 mL	0.0835 mL	0.1671 mL	0.4176 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.