1800229-46-2
Chemical Structure
DOTA-GA-maleimide
- CAS No.: 1800229-46-2
- Formula:C25H38N6O11
- Molecular Weight:598.60
InChIKey: NOHFVHQBEMKKMB-UHFFFAOYSA-N
SMILES: O=C(CN1CCN(CCN(C(CCC(NCCN2C(C=CC2=O)=O)=O)C(O)=O)CCN(CC1)CC(O)=O)CC(O)=O)O
Biological Activity: DOTA-GA-maleimide is a bifunctional chelator with protein conjugation and radiometal chelation capabilities. DOTA-GA-maleimide forms stable complexes with 111In and conjugates with proteins via maleimide chemistry. DOTA-GA-maleimide conjugates with LFn, enabling 111In radiolabeling of LFn through direct or pre-labeling strategies. Radiolabeled LFn is applicable to MMP activity imaging studies. DOTA-GA-maleimide is used in cancer research[1].
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DOTA-GA-maleimide | 99.72% | DOTA-GA-maleimide is a bifunctional chelator with protein conjugation and radiometal chelation capabilities. DOTA-GA-maleimide forms stable complexes with 111In and conjugates with proteins via maleimide chemistry. DOTA-GA-maleimide conjugates with LFn, enabling 111In radiolabeling of LFn through direct or pre-labeling strategies. Radiolabeled LFn is applicable to MMP activity imaging studies. DOTA-GA-maleimide is used in cancer research. | ||||||||||||||||||||
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Keywords
