FSDD0I

Cat. No.: HY-146180: FAQs
Data Sheet Handling Instructions

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FSDD0I is an albumin-binding fibroblast activation protein (FAP) ligand. FSDD0I can be labeled with ⁶⁸Ga and ¹⁷⁷Lu for single photon emission computed tomography (SPECT) imaging.

For research use only. We do not sell to patients.

FSDD0I Chemical Structure

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Description	FSDD0I is an albumin-binding fibroblast activation protein (FAP) ligand. FSDD0I can be labeled with ⁶⁸Ga and ¹⁷⁷Lu for single photon emission computed tomography (SPECT) imaging^[1].
Molecular Weight	1572.52
Formula	C₆₈H₉₂F₂IN₁₅O₁₆S
SMILES	FC(F)(CN1C(CNC(C2=CC=NC3=CC=C(C=C32)OCCCN4CCN(CC4)C(CCC(NCCCC[C@H](NC(CCCC5=CC=C(C=C5)I)=O)C(NCCSC(C(N6CCNC(CN7CCN(CCN(CCN(CC7)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O)CC6=O)=O)=O)=O)=O)=O)C[C@]1(C#N)[H]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (264 KB) Handling Instructions (2659 KB)
References	[1]. Meng L, et, al. Rational Design and Pharmacomodulation of Protein-Binding Theranostic Radioligands for Targeting the Fibroblast Activation Protein. J Med Chem. 2022 Jun 23;65(12):8245-8257. [Content Brief]

FSDD0I Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FSDD0IFAPFibroblast activation proteinfibroblast activation protein68Ga177Lusingle photon emission computed tomographySPECTimagingInhibitorinhibitorinhibit

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FSDD0I

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