PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1)
PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1) is a matrix materia, with lactic acid (LA):glycolic acid (GA) = 15:1, that acts as anti-cancer drug delivery. PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1) can improve a drug's bioavailability, efficacy, water solubility, drug encapsulation efficiency, sustained drug release, and to minimize undesirable toxicity.
For research use only. We do not sell to patients.
- Molecular Weight:Average Mn (1500-1500-1500)
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
PLGA‑PEG‑PLGA is an amphiphilic triblock copolymer, which combines the biodegradability of PLGA and the excellent biocompatibility of PEG, and can self‑assemble into core‑shell micelles in aqueous solution[1][2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight Average Mn (1500-1500-1500)
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SMILES
[H]OC(C)C(OCC(OCCOC(C(C)OC(CO[H])=O)=O)=O)=O.[x].[y].[m].[x].[y].[n].[m]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Xiufen Chen, et al. PLGA-PEG-PLGA triblock copolymeric micelles as oral drug delivery system: In vitro drug release and in vivo pharmacokinetics assessment. J Colloid Interface Sci. 2017 Mar 15:490:542-552. [Content Brief]
[2]. Yuan Gao, et al. A thermo-sensitive PLGA-PEG-PLGA hydrogel for sustained release of docetaxel. J Drug Target. 2011 Aug;19(7):516-27. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1) Related Classifications
HY-156829A Related Classifications
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