NF(N-Me)GA(N-Me)IL (Synonyms: Amylin (22-27) [NMeG24, NMeI26], human (IAPP))

Cat. No.: HY-P5514: FAQs
Data Sheet Handling Instructions

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NF(N-Me)GA(N-Me)IL is a biological active peptide. (This amino acids 22 to 27 fragment is a modification of the human islet amyloid polypeptide hIAPP (NFGAIL) with N-methylation of the amide bonds at G24 and I26. The introduction of two N-methyl rests in the amyloid-core-containing sequence NFGAIL converts this amyloidogenic and cytotoxic sequence into non-amyloidogenic and non-cytotoxic peptide. The peptide is able to bind with high-affinity full-length hIAPP and to inhibit its fibrillogenesis.)

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NF(N-Me)GA(N-Me)IL Chemical Structure

CAS No. : 409085-42-3

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Description	NF(N-Me)GA(N-Me)IL is a biological active peptide. (This amino acids 22 to 27 fragment is a modification of the human islet amyloid polypeptide hIAPP (NFGAIL) with N-methylation of the amide bonds at G24 and I26. The introduction of two N-methyl rests in the amyloid-core-containing sequence NFGAIL converts this amyloidogenic and cytotoxic sequence into non-amyloidogenic and non-cytotoxic peptide. The peptide is able to bind with high-affinity full-length hIAPP and to inhibit its fibrillogenesis.)
Molecular Weight	661.79
Formula	C₃₂H₅₁N₇O₈
CAS No.	409085-42-3
Sequence	Asn-Phe-{Sar}-Ala-{Ile(N-Me)}-Leu
Sequence Shortening	NF-{Sar}-A-{Ile(N-Me)}-L
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (240 KB) Handling Instructions (2659 KB)

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NF(N-Me)GA(N-Me)IL409085-42-3Amylin (22-27) [NMeG24, NMeI26], human (IAPP)OthersInhibitorinhibitorinhibit

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NF(N-Me)GA(N-Me)IL (Synonyms: Amylin (22-27) [NMeG24, NMeI26], human (IAPP))

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