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JHU395 

Cat. No.: HY-128775
Handling Instructions

JHU395 is an orally-bioavailable and a plasma stable lipophilic glutamine antagonists (GA) prodrug. JHU395 delivers 6-diazo-5-oxo-L-norleucine (DON) to malignant peripheral nerve sheath tumor (MPNST) in vitro and in vivo, and has antitumor activity in MPNST.

For research use only. We do not sell to patients.

JHU395 Chemical Structure

JHU395 Chemical Structure

CAS No. : 2079938-92-2

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Description

JHU395 is an orally-bioavailable and a plasma stable lipophilic glutamine antagonists (GA) prodrug. JHU395 delivers 6-diazo-5-oxo-L-norleucine (DON) to malignant peripheral nerve sheath tumor (MPNST) in vitro and in vivo, and has antitumor activity in MPNST[1].

Molecular Weight

447.48

Formula

C₂₂H₂₉N₃O₇

CAS No.

2079938-92-2

SMILES

O=C(C(C)(C)C)OC(OC(N[[email protected]@H](CCC(C=[N+]=[N-])=O)C(OC(C)C)=O)=O)C1=CC=CC=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

JHU395JHU 395JHU-395OthersInhibitorinhibitorinhibit

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JHU395
Cat. No.:
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