2079938-92-2
2079938-92-2
Chemical Structure
JHU395
- CAS No.: 2079938-92-2
- Formula:C22H29N3O7
- Molecular Weight:447.48
IUPAC Name: isopropyl (2S)-6-diazo-5-oxo-2-(((phenyl(pivaloyloxy)methoxy)carbonyl)amino)hexanoate
InChIKey: QQIBFRQTTLIECS-KKFHFHRHSA-N
SMILES: O=C(C(C)(C)C)OC(OC(N[C@@H](CCC(C=[N+]=[N-])=O)C(OC(C)C)=O)=O)C1=CC=CC=C1
Biological Activity: JHU395 is an orally-bioavailable and a plasma stable lipophilic glutamine antagonists (GA) proagent. JHU395 delivers 6-diazo-5-oxo-L-norleucine (DON) to malignant peripheral nerve sheath tumor (MPNST) in vitro and in vivo, and has antitumor activity in MPNST[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JHU395 | 99.69% | JHU395 is an orally-bioavailable and a plasma stable lipophilic glutamine antagonists (GA) proagent. JHU395 delivers 6-diazo-5-oxo-L-norleucine (DON) to malignant peripheral nerve sheath tumor (MPNST) in vitro and in vivo, and has antitumor activity in MPNST. | ||||||||||||||||||||
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References
Keywords
