AIE-GA
AIE-GA is a Golgi apparatus (GA) fluorescent probe (green channel: λex = 405 nm, λem = 500-700 nm). AIE-GA has a favourable binding ability to interact with COX-2. AIE-GA binds to the cyclooxygenase catalytic site of COX-2.
For research use only. We do not sell to patients.
- CAS No.: 2653341-16-1
- Formula: C33H25N3O2S
- Molecular Weight:527.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
For Golgi apparatus staining, cells were first incubated with ACQ-GA (2 μM) and AIE-GA (2 μM), respectively. Then Golgi Tracker Red (333 μg/mL) was added and incubated at 37 °C for 30 min, and the medium was removed and the cells were rinsed with phosphate buffered saline (PBS) three times and then imaged under a confocal microscope[1].
Loss in fluorescence of HeLa cells stained with ACQ-GA (2 μM), AIE-GA (2 μM) and Golgi Tracker Red (333 μg/mL) with increasing the number of scans of laser irradiation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2653341-16-1
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Molecular Weight 527.64
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Formula C33H25N3O2S
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SMILES
N#C/C(C1=CC=C(C2=CC=C(S(N)(=O)=O)C=C2)C=C1)=C\C3=CC=C(N(C4=CC=CC=C4)C5=CC=CC=C5)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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