Octyl gallate
Based on 3 publication(s) in Google Scholar
Octyl gallate (Progallin O) is widely used as a food additive, with antimicrobial and antioxidant activity. Octyl gallate (Progallin O) shows selective and sensitive fluorescent property. Octyl gallate shows a marked antiviral effect against HSV-1, vesicular stomatitis virus (VSV) and poliovirus.
For research use only. We do not sell to patients.
- Purity: 99.53%
- CAS No.: 1034-01-1
- Formula: C15H22O5
- Molecular Weight:282.33
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) Octyl gallate
More-
Cell Proliferation/Viability Assay
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IF
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RT-PCR
Biological Activity
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HSV-1 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| B16-F10 | IC50 |
45 μM
Compound: G8
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Cytotoxicity against mouse B16F10 cells
Cytotoxicity against mouse B16F10 cells
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[PMID: 23291333] |
| CCRF-CEM | CC50 |
11 μM
Compound: 6
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Cytotoxicity against human CEM cells assessed as inhibition of cell proliferation
Cytotoxicity against human CEM cells assessed as inhibition of cell proliferation
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[PMID: 25617695] |
| CCRF-CEM | EC50 |
>2 μM
Compound: 6
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Antiviral activity against HIV1 3B infected in human CEM cells assessed as reduction in virus-induced cytopathicity after 4 to 5 days by microscopy based syncytium cell formation assay
Antiviral activity against HIV1 3B infected in human CEM cells assessed as reduction in virus-induced cytopathicity after 4 to 5 days by microscopy based syncytium cell formation assay
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[PMID: 25617695] |
| CCRF-CEM | EC50 |
>2 μM
Compound: 6
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Antiviral activity against HIV2 ROD infected in human CEM cells assessed as reduction in virus-induced cytopathicity after 4 to 5 days by microscopy based syncytium cell formation assay
Antiviral activity against HIV2 ROD infected in human CEM cells assessed as reduction in virus-induced cytopathicity after 4 to 5 days by microscopy based syncytium cell formation assay
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[PMID: 25617695] |
| CCRF-CEM | IC50 |
50 μM
Compound: G8
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Cytotoxicity against human CEM cells
Cytotoxicity against human CEM cells
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[PMID: 23291333] |
| CCRF-CEM | IC50 |
58.5 μM
Compound: OG
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Cytotoxicity against human CCRF-CEM cells after 48 hrs by neutral red assay
Cytotoxicity against human CCRF-CEM cells after 48 hrs by neutral red assay
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[PMID: 24568614] |
| L1210 | IC50 |
22 μM
Compound: G8
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Cytotoxicity against mouse L1210 cells
Cytotoxicity against mouse L1210 cells
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[PMID: 23291333] |
| L929 | IC50 |
1 μM
Compound: G8
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Cytotoxicity against mouse L929 cells
Cytotoxicity against mouse L929 cells
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[PMID: 23291333] |
Octyl gallate has antimicrobial activity over H. pylori, with a minimum inhibitory concentration (MIC) value of 125 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1034-01-1
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Appearance Solid
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Molecular Weight 282.33
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Formula C15H22O5
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Color White to off-white
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SMILES
O=C(OCCCCCCCC)C1=CC(O)=C(O)C(O)=C1
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Synonyms
n-Octyl gallate; Stabilizer GA 8
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (3)
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Journal Impact Factor
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Most Recent
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Virol Sin
Development of the reverse genetics system for viral hemorrhagic septicemia virus genotype IVa and its application in antiviral compound screening. [Abstract]2025 Dec 27:S1995-820X(25)00177-4. PMID: 41461367
Octyl gallate purchased from MedChemExpress. Usage Cited in: Virol Sin. 2025 Dec 27:S1995-820X(25)00177-4. [Abstract]
Cells were treated with Octyl gallate at concentrations ranging from 0 to 100 μmol/L for 4 days, and cell viability was determined using the Cell Counting Kit-8 (CCK-8) assay.
Octyl gallate purchased from MedChemExpress. Usage Cited in: Virol Sin. 2025 Dec 27:S1995-820X(25)00177-4. [Abstract]
Fluorescence microscopy imaging of FHM cells infected with rVHSV-EGFP (rescued from FHM cells, MOI = 0.1) after treatment with varying concentrations of Octyl gallate (1, 2, 3, 4, 5 μM) to assess GFP fluorescence intensity.
Octyl gallate purchased from MedChemExpress. Usage Cited in: Virol Sin. 2025 Dec 27:S1995-820X(25)00177-4. [Abstract]
FHM cells were infected with rVHSV-EGFP (rescued from FHM cells, MOI = 0.1) and treated with Xanthohumol (10 μmol/L), Octyl gallate (5 μmol/L), or Rottlerin (10 μmol/L) at indicated time-points, which represented the stage of viral attachment, internalization or replication, respectively.
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Vet Microbiol
The Chinese medicine monomer Schisandrin C inhibits PRRSV infection by regulating the OGT-PI3K/AKT/mTOR signaling pathway. [Abstract]2026 May:316:110992. PMID: 41865607 -
Solvent & Solubility
DMSO : 125 mg/mL (442.74 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Wolf VG, et al. Octyl gallate, a food additive with potential beneficial properties to treat Helicobacter pylori infection. Food Funct. 2017 Jul 19;8(7):2500-2511. [Content Brief]
[2]. Wang Q, et al. Octyl gallate: An antioxidant demonstrating selective and sensitive fluorescent property. Food Chem. 2017 Mar 15;219:268-273. [Content Brief]
[3]. Uozaki M, et al. Antiviral effect of octyl gallate against DNA and RNA viruses. Antiviral Res. 2007 Feb;73(2):85-91. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5420 mL | 17.7098 mL | 35.4195 mL | 88.5489 mL |
| 5 mM | 0.7084 mL | 3.5420 mL | 7.0839 mL | 17.7098 mL | |
| 10 mM | 0.3542 mL | 1.7710 mL | 3.5420 mL | 8.8549 mL | |
| 15 mM | 0.2361 mL | 1.1807 mL | 2.3613 mL | 5.9033 mL | |
| 20 mM | 0.1771 mL | 0.8855 mL | 1.7710 mL | 4.4274 mL | |
| 25 mM | 0.1417 mL | 0.7084 mL | 1.4168 mL | 3.5420 mL | |
| 30 mM | 0.1181 mL | 0.5903 mL | 1.1807 mL | 2.9516 mL | |
| 40 mM | 0.0885 mL | 0.4427 mL | 0.8855 mL | 2.2137 mL | |
| 50 mM | 0.0708 mL | 0.3542 mL | 0.7084 mL | 1.7710 mL | |
| 60 mM | 0.0590 mL | 0.2952 mL | 0.5903 mL | 1.4758 mL | |
| 80 mM | 0.0443 mL | 0.2214 mL | 0.4427 mL | 1.1069 mL | |
| 100 mM | 0.0354 mL | 0.1771 mL | 0.3542 mL | 0.8855 mL |