Search Result
Results for "
Synthetic intermediate
" in MedChemExpress (MCE) Product Catalog:
26
Biochemical Assay Reagents
8
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W002603
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- HY-75813
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Biochemical Assay Reagents
Akt
5-HT Receptor
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Neurological Disease
Cancer
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2-Aminonicotinaldehyde is a synthetic intermediate. 2-Aminonicotinaldehyde can be used for the synthesis of 5-HT3 receptor antagonists, AKT inhibitors, and other compounds. 2-Aminonicotinaldehyde is applicable to research on depression and cancers (including hepatocellular carcinoma) .
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- HY-100083
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HIV
Drug Intermediate
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Infection
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Dolutegravir intermediate-1 (Compound 11) is a synthetic intermediate. Dolutegravir intermediate-1 can be used to synthesize Dolutegravir (HY-13238). Dolutegravir is an Integrase inhibitor with potential applications in HIV-1 infection research .
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- HY-17578
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L-688786
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Drug Intermediate
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Infection
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Pneumocandin B0 (L-688786) is the precursor of the synthetic antifungal agent Cancidas (Caspofungin acetate) (HY-17006). Pneumocandin B0 can be isolated from fungus Glarea lozoyensis .
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- HY-128753
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Endogenous Metabolite
Drug Intermediate
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Metabolic Disease
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D-Lyxose is an endogenous metabolite. D-Lyxose is a rare pentose with significant potential for pharmaceutical synthesis. D-Lyxose serves as a starting material for antitumor agents (such as α-galactosylceramide-based immunostimulants). D-Lyxose acts as a precursor for L-nucleoside analogs used in the development of antiviral drugs. D-Lyxose can be used as a synthetic intermediate for other rare sugars (such as L-ribose) .
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- HY-W008321
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Biochemical Assay Reagents
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Metabolic Disease
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6-Bromo-3,4-dihydro-1 (2H)-naphthalenone is a synthetic intermediate. 6-Bromo-3,4-dihydro-1 (2H)-naphthalenone can be used for the synthesis of 2-Benzyl-6-bromo-3,4-dihydro-1 (2H)-naphthalenone. 6-Bromo-3,4-dihydro-1 (2H)-naphthalenone can be applied to the development of hypoglycemic agents .
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- HY-76562
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- HY-69142
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- HY-34590
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Drug Intermediate
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Cancer
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3-Amino-2,6-piperidinedione is a synthetic intermediate that has been used to design antitumor compounds .
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- HY-W007690
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- HY-21629
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- HY-40040
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Drug Intermediate
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Infection
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(S)-1-Boc-3-methylpiperazine is a synthetic intermediate for indole-piperazine hybrid antimicrobial agent preparation. (S)-1-Boc-3-methylpiperazine can be used for research on bacterial infection and fungal infection .
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- HY-W016859
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Drug Intermediate
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Others
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5-Chlororesorcinol dimethyl ether is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W098322
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Drug Intermediate
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Others
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Z-Lys-OMe hydrochloride is a synthetic intermediate that can be used in the synthesis of peptide enzyme substrates and lysine cationic surfactants.
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- HY-W009498
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Drug Intermediate
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Others
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2,5-Dibromo-4-methylpyridine is a synthetic pyridine derivative and serves as an important intermediate .
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- HY-151661
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L-azidovaline (CHA)
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ADC Linker
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Others
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N3-L-Val-OH (CHA) is a click chemistry containing an azide group, a valine derivative. N3-L-Val-OH (CHA) can also be used as a synthetic intermediate for Valaciclovir (Valacyclovir) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-W000933
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Drug Intermediate
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Others
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Ethylboronic acid is an organic boron compound that can be used as a synthetic intermediate .
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- HY-60346
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2-Carboxy-Pyrimidine
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Drug Intermediate
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Infection
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2-Pyrimidinecarboxylic acid is a synthetic intermediate useful for pharmaceutical synthesis .
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- HY-60347A
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Pyrimidin-2-ylmethanamine hydrochloride
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Drug Intermediate
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Others
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2-Aminomethylpyrimidine (Pyrimidin-2-ylmethanamine) hydrochloride is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W017769
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Pyrimidin-4-ylmethanamine
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Drug Intermediate
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Others
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4-Pyrimidine methanamine (Pyrimidin-4-ylmethanamine) is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-118226
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Drug Intermediate
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Others
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5,6,7,8-Tetrahydro-2-naphthoic acid is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-Z0085
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Drug Intermediate
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Others
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2-Chloro-N-methyl-N-(4-nitrophenyl)acetamide is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-13952
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Drug Intermediate
Bacterial
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Others
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TP-808 is a key enone intermediate for the discovery and manufacture of Tetracycline (HY-A0107) analogs and synthetic tetracyclines including eravacycline .
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- HY-W076298
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SARS-CoV
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Infection
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Remdesivir intermediate-1 is a synthetic intermediate that can be used in the synthesis of Remdesivir (HY-104077).
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- HY-W128579
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Drug Intermediate
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Others
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2-Pyrimidinepropanoic acid is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W590911
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- HY-117052
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- HY-W024652
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Drug Intermediate
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Others
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4,5-Dimethylimidazole is a nitrogen-containing heterocyclic compound and is a synthetic intermediate .
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- HY-W011657
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Drug Intermediate
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Others
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tert-Butyl 4-(bromomethyl)benzoate is a synthetic intermediate useful for compound synthesis .
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- HY-117020
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Drug Intermediate
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Others
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Methyl (S)-(-)-N-Z-aziridine-2-carboxylate is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-43001
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- HY-41004
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Drug Intermediate
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Cancer
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3-Isoquinolinecarboxylic acid (compound 2) is a synthetic intermediate that has been used to design antitumor compounds .
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- HY-W007977
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Drug Intermediate
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Cancer
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4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline (Compound 11 and 15) is a building block and synthetic intermediate, which can be used as a precursor in the synthesis of receptor tyrosine kinase (RTK) inhibitors, dual RTK and histone deacetylase (HDAC) inhibitors, and anticancer agents. 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline can also be used to synthesize EGFR inhibitors, including Erlotinib (HY-50896), with antiproliferative activity .
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- HY-N7130
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- HY-52102
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Drug Intermediate
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Others
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2-(Chloromethyl)pyrimidine hydrochloride is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W020655
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D-(-)-Mandelic Acid Benzyl Ester
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Drug Intermediate
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Others
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(R)-Benzyl mandelate (D-(-)-Mandelic Acid Benzyl Ester) is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W017825
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- HY-135888
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- HY-W153810
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Drug Intermediate
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Others
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2-Methyl-4-phenyl thiazole is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-76548
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tert-Butyl p-methylbenzoate
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Drug Intermediate
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Others
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tert-Butyl p-Toluate (tert-Butyl p-methylbenzoate) is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-119414
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L-N,N-Dimethylvaline
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Drug Intermediate
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Others
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N,N-Dimethyl-L-valine (L-N,N-Dimethylvaline) is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W058182
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Drug Intermediate
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Others
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7-Chlorothieno[2,3-c]pyridine is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W099761
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- HY-W061399
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3-Aminotetrahydrofuran
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Drug Intermediate
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Others
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(S)-Tetrahydrofuran-3-ylamine (3-Aminotetrahydrofuran) is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-Y1118
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Drug Intermediate
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Others
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6,7-Dihydroquinolin-8(5H)-one is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-75814
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p-Isopropoxybenzoic acid
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Biochemical Assay Reagents
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Others
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4-Isopropoxybenzoic acid (p-Isopropoxybenzoic acid) is an aromatic carboxylic acid organic compound that can be used as a synthetic intermediate in organic synthesis such as pesticides .
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- HY-30217
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L-alpha-Hydroxyisovaleric acid
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Drug Intermediate
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Others
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(S)-2-Hydroxy-3-methylbutanoic acid (L-alpha-Hydroxyisovaleric acid) is a synthetic intermediate useful for pharmaceutical synthesis .
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- HY-W012428
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Drug Intermediate
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Others
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2-(3-Pyridyl)-4-methyl-thiazole-5-carboxylic acid is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-41240
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- HY-34190
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- HY-W015805
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- HY-W030112
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Drug Intermediate
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Others
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2-Pyridinecarboxamidoxime is a synthetic intermediate that can be used for pharmaceutical synthesis.
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- HY-78975
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Drug Intermediate
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Others
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2-(Hydroxymethyl)-pyrimidine is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W046161
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NSC 131886
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Drug Intermediate
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Others
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4-Aminomethylindole (NSC 131886) is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-169497
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Drug Intermediate
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Others
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MTDB is a synthetic intermediate in the synthesis of the clickable RNA pseudoknot binder MTDB-Alkyne.
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- HY-W028160
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Drug Intermediate
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Others
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5-(2-Aminopyridyl)amide oxime is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W057459
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Drug Intermediate
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Others
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(R)-3-Oxo-cyclopentanecarboxylic acid methyl ester is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-159053
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- HY-118436
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Drug Intermediate
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Others
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3-Methyl-2-quinoxalinone is a synthetic intermediate, and can be used for pharmaceutical synthesis .
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- HY-135200
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4-Amino-N'-hydroxybenzenecarboximidamide
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Drug Intermediate
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Others
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4-Amino benzamidoxime (4-Amino-N'-hydroxybenzenecarboximidamide) is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W043311
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Pyrimidine-4-carboxylicacidmethylester
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Drug Intermediate
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Others
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Methyl pyrimidine-4-carboxylate (Pyrimidine-4-carboxylicacidmethylester) is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W063149
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Drug Intermediate
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Others
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(1S,3R)-3-Aminocyclopentanol is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W028809
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Drug Intermediate
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Others
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5-Methyl-4-phenyl-2-thiazolamine is a synthetic intermediate that can be used for pharmaceutical synthesis.
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- HY-123029
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NSC 99006
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Drug Intermediate
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Others
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5,6,7,8-Tetrahydro-2-quinolone (NSC 99006) is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W061761
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Drug Intermediate
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Others
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(1R,3S)-3-Aminocyclopentane carboxylic acid is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W007287
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Drug Intermediate
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Others
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5-Methoxyquinolin-8-amine is a synthetic intermediate that can be used to prepare N-phthaloyl amino acid derivatives .
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- HY-Y0135R
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- HY-113908
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Drug Intermediate
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Others
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(1S,3S)-3-Aminomethyl-cyclopentanol is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W345015
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Drug Intermediate
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Others
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2-Methyl-3-pyrimidin-2-yl-propionic acid is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W278906
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Drug Intermediate
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Others
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Ethyl 2-(3-hydroxyphenyl)-4-methylthiazole-5-carboxylate is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W106109
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Drug Intermediate
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Others
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2-Hydroxy-4-methylquinoline is a synthetic intermediate. 2-Hydroxy-4-methylquinoline is formed via cyclization of acetoacetanilide under the action of concentrated sulfuric acid through the Conrad-Limpach-Knorr synthesis. 2-Hydroxy-4-methylquinoline can be used in studies related to the synthesis of chemotherapeutic agents .
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- HY-W061629
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- HY-135187
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Drug Intermediate
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Others
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8-Isoquinoline methanamine hydrochloride is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W333389
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Drug Intermediate
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Others
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4-Biphenylthio carboxamide is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W569932
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- HY-W357919
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Drug Intermediate
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Others
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3-Thio-pheneacrylic acid methyl ester is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-114870
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o-Tolylamidoxime; 2-methylbenzamide Oxime
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Drug Intermediate
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Others
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2-Methyl benzamideoxime (o-Tolylamidoxime) is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W128619
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3-Aminothiobenzamide
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Drug Intermediate
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Others
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3-Aminobenzothioamide (3-Aminothiobenzamide) is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W700710
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Drug Intermediate
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Others
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(Rac)-7-Methoxy propranolol is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W350880
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Drug Intermediate
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Others
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8-(1-Piperazinyl)-isoquinoline hydrochloride is a synthetic intermediate, and can be used for pharmaceutical synthesis .
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- HY-W057450
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Drug Intermediate
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Others
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(S)-3-Oxo-cyclopentanecarboxylic acid methyl ester is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W700173
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- HY-W267062A
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- HY-100083R
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Reference Standards
HIV
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Others
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Dolutegravir intermediate-1 (Standard) is the analytical standard of Dolutegravir intermediate-1 (HY-100083). This product is intended for research and analytical applications. Dolutegravir intermediate-1 is a synthetic intermediate of Dolutegravir extracted from patent WO 2016125192 A2. Dolutegravir is an integrase inhibitor developed for the treatment of human immunodeficiency virus (HIV)-1 infection.
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- HY-W094155
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Drug Intermediate
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Others
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Methyl (1S)-3-oxocyclopentaneacetate is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W212902
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Drug Intermediate
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Others
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2-Pyrimidin-2-yl-propionic acid is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W711166
-
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Drug Intermediate
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Others
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4-(2-Acetoxyacetyl)phenyl acetate is a synthetic intermediate that has been used in the synthesis of phenethylamine metabolites.
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- HY-169494
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Drug Intermediate
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Others
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Karrikinolide 3-ethyl ester a synthetic intermediate that can be used in the synthesis of butanolide seed germination stimulants.
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- HY-169321
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-
- HY-W338244
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Drug Intermediate
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Others
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2-Amino-4-(1-adamantyl)thiazole is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-136665
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tert-Butoxycarbonyl-D-phenylalanyl-L-proline
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Drug Intermediate
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Others
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Boc-D-Phe-Pro-OH (tert-Butoxycarbonyl-D-phenylalanyl-L-proline) is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-177965
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Drug Intermediate
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Others
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Boc-protected photo-Leu(tBu) (compound 4) is a synthetic intermediate of diazirine-containing probe (photo-Met) .
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- HY-Z17392
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Drug Intermediate
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Others
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Sunitinib impurity 61 (Compound 5h) is an intermediate. Sunitinib impurity 61 is a synthetic intermediate or impurity of Sunitinib (HY-10255A) and can be used as a reference standard for purity analysis and quality control .
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- HY-179365
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β-NTA dihydrochloride
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Drug Intermediate
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Others
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β-Naltrexamine (β-NTA) dihydrochloride is a key synthetic intermediate used in the preparation of irreversible ligands for opioid receptors .
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- HY-42223
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Drug Intermediate
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Others
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(1R,3S)-3-Amino-cyclopentanol is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-33921
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4-Piperazinoindole hydrochloride
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Drug Intermediate
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Others
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4-(1-Piperazinyl)-1H-Indole (4-Piperazinoindole) hydrochloride is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-118475
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6-(1-Piperazinyl)-isoquinoline hydrochloride
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Drug Intermediate
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Others
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6-Piperazin-1-yl-isoquinoline (6-(1-Piperazinyl)-isoquinoline) hydrochloride is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-113877
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3-amino-N'-hydroxybenzene-1-carboximidamide
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Drug Intermediate
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Others
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3-Amino benzamidoxime (3-amino-N'-hydroxybenzene-1-carboximidamide) is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-124049
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Drug Intermediate
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Others
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Ethyl 4-methyl-2-(2-thienyl)-thiazole-5 carboxylate is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-172831A
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Drug Intermediate
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Others
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(1S,3R)-3-Hydroxycyclopentane acetic acid is a synthetic intermediate and can be used for pharmaceutical synthesis.
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- HY-W755107
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Drug Intermediate
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Others
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(1S,3R)-3-Hydroxycyclopentane carboxylic acid methyl ester is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W034099
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Drug Intermediate
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Others
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(1R,3R)-3-Hydroxycyclopentane carboxylic acid methyl ester is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-Z4488
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Drug Intermediate
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Cancer
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5-Dibromomethyl anastrozole is a synthetic intermediate in the synthesis of the aromatase/CYP19A1 inhibitor Anastrozole (HY-14274).
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- HY-W394612
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Drug Intermediate
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Others
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(1R,3S)-3-Hydroxycyclopentane carboxylic acid methyl ester is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W088629
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Drug Intermediate
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Cardiovascular Disease
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D-2-Aminoglutarimide hydrochloride is a synthetic intermediate that can be used in the synthesis of hydantoins with anti-angiogenic and cancer cell differentiation-inducing activities.
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- HY-114756
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Drug Intermediate
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Others
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2-(2-Pyridyl)-4-methyl-thiazole-5-carboxylic acid is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W404362
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Drug Intermediate
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Others
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2,4,6-Trihydroxy-3-prenylacetophenone (compound 13) is a prenylated acetophenone derivative that can be used as a synthetic intermediate .
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- HY-W327038
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Drug Intermediate
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Others
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7-Piperazin-1-yl-thieno[2,3-c] pyridine hydrochloride is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W045268
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Drug Intermediate
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Others
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Ethyl-2-amino-4-phenyl thiophene-3-carboxylate is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-W040417
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PI3K
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Others
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Boc-L-cyclobutylglycine is a Boc-protected L-cyclic amino acid and synthetic intermediate in the preparation of purinyl quinazolinone PI3Kδ inhibitors .
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- HY-W017115
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Thio-p-anisamide
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Drug Metabolite
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Others
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4-Methoxybenzenecarbothioamide is a synthetic intermediate useful for pharmaceutical synthesis, which can be synthesized by 4-methoxy benzamide and phosphorus pentasulfide reactions .
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- HY-W058423
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Drug Intermediate
MAP4K
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Cardiovascular Disease
Inflammation/Immunology
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6-Bromo-3-fluoropyridine-2-carbaldehyde (synthetic intermediate of Compound I-90) is a synthetic intermediate. 6-Bromo-3-fluoropyridine-2-carbaldehyde can be used in the synthesis of HPK1 inhibitors. 6-Bromo-3-fluoropyridine-2-carbaldehyde is applicable to research on immune diseases and hematological diseases .
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- HY-172831
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Drug Intermediate
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Others
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(1S,3S)-3-Hydroxycyclopentane acetic acid (Compound 8) is a synthetic intermediate used in the synthesis of compounds .
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- HY-W329522
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Drug Intermediate
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Others
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Ethyl-2-(2-pyridyl)-4-(bromomethyl)-Thiazole-5-Carboxylate is a synthetic intermediate useful for pharmaceutical synthesis.
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-
- HY-129844
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N'-hydroxy-4-phenylbenzene-1-carboximidamide
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Drug Intermediate
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Others
|
|
Biphenyl-4-amidoxime (N'-hydroxy-4-phenylbenzene-1-carboximidamide) is a synthetic intermediate useful for pharmaceutical synthesis.
|
-
- HY-W012618
-
|
|
Drug Intermediate
|
Neurological Disease
|
|
1-Phenyl-1-propanol is used as a chiral building block and synthetic intermediate in the pharmaceutical industries. 1-Phenyl-1-propanol is an intermediate of anti-depressant agent Fluoxetine (HY-B0102) .
|
-
- HY-W320685
-
|
|
Drug Intermediate
|
Others
|
|
(S)-N-Boc-L-homoserine ethyl ester is a synthetic intermediate in the synthesis of unsaturated caprolactams and monomer units for oxy-peptide nucleic acids from the starting material L-homoserine.
|
-
- HY-W088558
-
|
|
Drug Intermediate
|
Others
|
|
Benzyl (1R,3R)-3-hydroxycyclopentane-1-carboxylate is a synthetic intermediate useful for pharmaceutical synthesis.
|
-
- HY-120021
-
|
|
Drug Intermediate
|
Others
|
|
tert-Butyl 4-(1H-indol-4-yl)piperazine-1-carboxylate is a synthetic intermediate useful for pharmaceutical synthesis..
|
-
- HY-123628
-
-
- HY-W350804
-
|
|
Drug Intermediate
|
Others
|
|
3-Pyrimidin-2-yl-2-pyrimidin-2-ylmethyl-propionic acid is a synthetic intermediate useful for pharmaceutical synthesis.
|
-
- HY-79576
-
|
Oestrone methyl ether; 3-O-Methylestrone
|
Drug Intermediate
|
Cancer
|
|
Estrone 3-methyl ether (Oestrone methyl ether; 3-O-Methylestrone) is a synthetic intermediate useful for synthesis of estrogen receptor modulator .
|
-
- HY-W007273
-
-
- HY-W010601
-
|
1-[(2R)-tetrahydrofuran-2-yl]methanamine
|
Drug Intermediate
|
Others
|
|
(R)-Tetrahydrofuran-2-yl-methylamine (1-[(2R)-tetrahydrofuran-2-yl]methanamine) is a synthetic intermediate useful for pharmaceutical synthesis.
|
-
- HY-134758
-
|
|
Drug Intermediate
|
Others
|
|
Dihydrovitamin K1 diacetate is a synthetic intermediate of Vitamin K1 (HY-N0684). Dihydrovitamin K1 diacetate can be oxidized to synthesize Vitamin K1 .
|
-
- HY-P4192
-
|
|
ADC Linker
|
Cancer
|
|
Fomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit .
|
-
- HY-W017851
-
|
|
Drug Intermediate
|
Neurological Disease
|
|
4-Phenyl-2-pyrrolidinone is a precursor and synthetic intermediate. 4-Phenyl-2-pyrrolidinone can be used as a precursor in the synthesis of compounds with anticonvulsant and nootropic activities and is an intermediate in the synthesis of bromodomain-containing protein 4 (BRD4) bromodomain 1 inhibitors .
|
-
- HY-W018778
-
-
- HY-W679892
-
|
|
Drug Intermediate
|
Others
|
|
N-(2,3-Dichlorophenyl)urea is a synthetic intermediate. N-(2,3-Dichlorophenyl)urea can be used to synthesize compounds with cytokinin activity .
|
-
- HY-W003592A
-
|
|
Drug Intermediate
|
Others
|
|
L-Orinithine lactam hydrochloride is a synthetic intermediate. L-Orinithine lactam (hydrochloride) can be used in the synthesis of dipeptidyl peptidase 4 (DPP-4) inhibitors, as well as signaling peptides .
|
-
- HY-I0308
-
-
- HY-32237
-
|
α-(4-chlorophenyl)pyridine-2-methanol
|
Drug Intermediate
|
Others
|
|
4-Chlorophenyl-2-pyridinylmethanol (α-(4-chlorophenyl)pyridine-2-methanol) is a synthetic intermediate useful for pharmaceutical synthesis.
|
-
- HY-W004788
-
|
5-Bromo-3,4-dihydro-2H-naphthalen-1-one
|
Drug Intermediate
|
Others
|
|
5-Bromotetralone (5-Bromo-3,4-dihydro-2H-naphthalen-1-one) is a synthetic intermediate useful for pharmaceutical synthesis.
|
-
- HY-41840
-
|
|
Drug Intermediate
|
Others
|
|
D-Glucurono-6,3-lactone acetonide is a acetone-protected derivative of D-Glucurono-6,3-lactone (HY-41982) that can be used as a synthetic intermediate.
|
-
- HY-69055
-
|
|
Drug Intermediate
|
Cardiovascular Disease
|
|
7-Bromoisoquinoline is a brominated isoquinoline and synthetic precursor that constructs the isoquinoline functional group at the C17 position of target molecules. 7-Bromoisoquinoline serves as a key synthetic intermediate for the synthesis of cortistatin A-derived anti-angiogenic steroidal analogs (e.g., 7-tributylstannyl isoquinoline). 7-Bromoisoquinoline .
|
-
- HY-152656
-
-
- HY-159622
-
|
|
Drug Intermediate
|
Cancer
|
|
Boc-Pip-C-oxotetrahydropyrimidin-bromophenyl is a synthetic intermediate for molecular glue. Boc-Pip-C-oxotetrahydropyrimidin-bromophenyl can be used in synthesis GSPT1 degrader-9 (HY-159610) .
|
-
- HY-W044805
-
|
4-Pyridin-4-yl-thiazol-2-ylamine
|
Drug Intermediate
|
Others
|
|
2-Amino-4-(4-pyridyl)-thiazole (4-Pyridin-4-yl-thiazol-2-ylamine) is a synthetic intermediate useful for pharmaceutical synthesis.
|
-
- HY-Y0185
-
|
|
Biochemical Assay Reagents
Drug Intermediate
|
Others
|
|
4'-Nitroacetophenone is a nitroaromatic compound. 4'-Nitroacetophenone is an important organic synthetic intermediate, which can be used for the synthesis of other active compounds such as Chloramphenicol (HY-B0239) .
|
-
- HY-107211
-
|
SL 7810 nucleus; A-30912 A nucleus
|
Fungal
Drug Intermediate
|
Infection
|
|
Echinocandin B nucleus (A-30912 A nucleus) is the reaction product catalyzed by Echinocandin B (HY-125723) deacylase. Echinocandin B nucleus serves as an intermediate for the synthesis of semi-synthetic antifungal agents .
|
-
- HY-W724743
-
|
|
Biochemical Assay Reagents
|
Cardiovascular Disease
|
|
Losartan azide is a click chemistry reagent containing an azide group and is a synthetic intermediate for the preparation of angiotensin AT1R-targeted renal PET imaging probe [18 F]fluoropyridine-losartan .
|
-
- HY-W002616
-
|
5-Bromooxindole
|
Drug Intermediate
|
Infection
|
|
5-Bromoindolin-2-one (5-Bromooxindole) is a synthetic intermediate. 5-Bromoindolin-2-one can be used for the synthesis of CDK2 inhibitors and antibacterial agents .
|
-
- HY-401369
-
|
|
Drug Intermediate
|
Cancer
|
|
NH2-Benzo[d][1,3]dioxole-CO-bicyclo[1.1.1]pentane-NH-TFA is a synthetic intermediate that can be used for ADCs synthesis .
|
-
- HY-32149
-
-
- HY-W412215
-
|
|
Biochemical Assay Reagents
Endogenous Metabolite
|
|
|
TTMAPP is a photocatalyst with the activity of promoting organic reactions. TTMAPP is widely used in chemical synthesis, especially in oxidation and reduction reactions. TTMAPP can also be used as a synthetic intermediate for bioactive molecules, which is of great significance for compound development.
|
-
- HY-W002642
-
|
2-Aminocyclopent-1-ene-1-carbonitrile
|
Biochemical Assay Reagents
|
Others
|
|
2-Amino-1-cyclopentene-1-carbonitrile (2-Aminocyclopent-1-ene-1-carbonitrile) is an important and universal synthetic intermediate in organic chemistry.
|
-
- HY-W095670
-
|
|
Drug Intermediate
|
Others
|
|
2,4,7-Trichloro-8-fluoropyridopyrimidine is a pyridopyrimidine synthetic intermediate of MRTX1133 (HY-134813), which can be used for the synthesis of non-covalent KRAS G12D inhibitors .
|
-
- HY-169261
-
-
- HY-138179
-
|
|
Bacterial
|
Infection
|
|
7-APRA is a semi-synthetic intermediate of cephalosporin antibiotics. 7-APRA has antibacterial activity and is mainly used in the synthesis of other Cefaclor (HY-B0198) and Cefprozil (HY-B0458A) .
|
-
- HY-118292
-
|
1,4-Diacetoxybenzene
|
Drug Intermediate
|
Others
|
|
Hydroquinone diacetate (1,4-Diacetoxybenzene) is a diester product and also a commonly used synthetic intermediate for agrochemicals and fine chemicals. Hydroquinone diacetate can be produced via the acetylation of hydroquinone (HY-B0951) with acetic anhydride .
|
-
- HY-40146
-
-
- HY-159623
-
|
|
Drug Intermediate
|
Cancer
|
|
Thalidomide 5-Pip-C-oxotetrahydropyrimidin-bromophenyl is a synthetic intermediate for molecular glues. Thalidomide 5-Pip-C-oxotetrahydropyrimidin-bromophenyl can be used to synthesize GSPT1 degrader-9 (HY-159610) .
|
-
- HY-W783015
-
|
|
Drug Intermediate
|
Others
|
|
3-((1-Carboxy-2-((5,5-dimethyl-4,5-dihydroisoxazol-3-yl)thio)ethyl)amino)-3-oxopropanoic acid is an important organic synthetic intermediate.
|
-
- HY-W007690S
-
-
- HY-175155
-
|
(1S,3S)-3-(Benzoyloxy)cyclopentanecarboxylic acid
|
Drug Intermediate
|
Others
|
|
(1S,3S)-3-Benzoic acid 3-carboxycyclopentyl ester ((1S,3S)-3-(Benzoyloxy)cyclopentanecarboxylic acid) is a synthetic intermediate and can be used for pharmaceutical synthesis.
|
-
- HY-W366582
-
|
|
Drug Intermediate
|
Others
|
|
7-Methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-amine is a synthetic intermediate useful for pharmaceutical synthesis.
|
-
- HY-W048545
-
|
β-D-Glucopyranuronic acid, methyl ester, 2,3,4-triacetate
|
Drug Intermediate
|
Infection
|
|
2,3,4-Tri-O-acetyl-β-D-glucuronide methyl ester (β-D-Glucopyranuronic acid, methyl ester, 2,3,4-triacetate) is a synthetic intermediate in the synthesis of prodrug forms of the antitumor antibiotic Daunomycin (HY-13062A).
|
-
- HY-W006202
-
|
(1S,3R)-3-[(tert-Butoxycarbonyl)amino]cyclopentanecarboxylic acid
|
Drug Intermediate
|
Others
|
|
BOC-(1S,3R)-3-aminocyclopentanecarboxylic acid ((1S,3R)-3-[(tert-Butoxycarbonyl)amino]cyclopentanecarboxylic acid) is a synthetic intermediate useful for pharmaceutical synthesis.
|
-
- HY-44087
-
|
|
Drug Intermediate
|
Others
|
|
Ethyl (E)-3-(1-pyrrolidinyl)crotonate is an organic synthetic intermediate of the enamine ester type. Ethyl (E)-3-(1-pyrrolidinyl)crotonate has a stable structure and strong reactivity, and is mainly used for the construction of heterocyclic compounds and drug molecules.
|
-
- HY-114799
-
|
4-Methyl-2-pyridin-4-ylthiazole-5-carboxylic acid
|
Drug Intermediate
|
Others
|
|
2-(4-Pyridyl)-4-methyl-thiazole-5-carboxylic acid (4-Methyl-2-pyridin-4-ylthiazole-5-carboxylic acid) is a synthetic intermediate useful for pharmaceutical synthesis.
|
-
- HY-W599025
-
|
|
Drug Intermediate
|
Cancer
|
|
5-Br-4-Cl-Pyrrolo-pyroxypyridine is a synthetic intermediate for molecular glues. 5-Br-4-Cl-Pyrrolo-pyroxypyridine can be used for synthesis GSPT1 degrader-9 (HY-159609) .
|
-
- HY-W017378
-
|
|
Drug Intermediate
|
Others
|
|
Trimethylhydroquinone is an active compound intermediate. Trimethylhydroquinone can condense with isophytol or phytol to produce synthetic Vitamin E (HY-B1278A). Trimethylhydroquinone serves as the parent compound for the synthesis of trimethylhydroquinone derivatives with antioxidant, anti-allergic, and 5-lipoxygenase inhibitory activities .
|
-
- HY-128994
-
|
|
Drug Intermediate
|
Cancer
|
|
GGFG-Exatecan is a synthetic intermediate for drug-linker conjugates used in antibody-drug conjugates (ADCs). GGFG-Exatecan consists of a glycyl-glycyl-phenylalanyl-glycine (GGFG) tetrapeptide linker and a DNA topoisomerase I inhibitor Exatecan (HY-13631). GGFG-Exatecan can be used for the study of cancer .
|
-
- HY-79334
-
|
|
Endogenous Metabolite
|
Others
|
|
(S)-(+)-1,2-Propanediol is an endogenous metabolite. (S)-(+)-1,2-Propanediol can be used as an organic solvent and diluent in drug preparations. (S)-(+)-1,2-Propanediol can also be used as a chiral synthetic intermediate and a substrate for enzyme research .
|
-
- HY-W003592R
-
|
|
Reference Standards
Drug Intermediate
|
Others
|
|
L-Orinithine lactam (Standard) is the analytical standard of L-Orinithine lactam. This product is intended for research and analytical applications. L-Orinithine lactam is a synthetic intermediate. L-Orinithine lactam can be used in the synthesis of dipeptidyl peptidase 4 (DPP-4) inhibitors, as well as signaling peptides .
|
-
- HY-206852
-
|
|
Drug Intermediate
Phosphodiesterase (PDE)
|
Neurological Disease
|
|
PF-06445974 precursor (Compound 28) is a nitro precursor and synthetic intermediate. PF-06445974 precursor can be used for the synthesis of PF-06445974 (HY-119190). PF-06445974 is a positron emission tomography (PET) compound that acts potently on PDE4B .
|
-
- HY-W003601
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-Bromo-4-fluoropyridine is a synthetic halogenated heterocyclic organic compound and a key intermediate in the pharmaceutical and agrochemical industries. 2-Bromo-4-fluoropyridine can be used to synthesize bioactive molecules through cross-coupling reactions, such as Suzuki coupling or Buchwald-Hartwig amination.
|
-
- HY-W036733
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Hydroxy-4-methylcyclohexanone is a useful synthetic reagent extracted from patent JP2009022162A. 4-Hydroxy-4-methylcyclohexanone can be used to synthesize trans-4-amino-1-methylcyclohexanol which is intermediate of pharmaceutical synthesis .
|
-
- HY-128994A
-
|
|
Drug Intermediate
|
Cancer
|
|
GGFG-Exatecan TFA is a synthetic intermediate for drug-linker conjugates used in antibody-drug conjugates (ADCs). GGFG-Exatecan TFA consists of a glycyl-glycyl-phenylalanyl-glycine (GGFG) tetrapeptide linker and a DNA topoisomerase I inhibitor Exatecan (HY-13631). GGFG-Exatecan TFA can be used for the study of cancer .
|
-
- HY-W698250
-
|
|
Biochemical Assay Reagents
Endogenous Metabolite
|
|
|
3-Ferrocenylpropionic anhydride is an important organic compound with good biological activity. 3-Ferrocenylpropionic anhydride is widely used in compound synthesis and can be used as a synthetic intermediate to participate in the production of a variety of biologically active compounds. 3-Ferrocenylpropionic anhydride exhibits potential anti-tumor properties by regulating specific enzyme activities.
|
-
- HY-76547
-
|
4-Methylbenzoic acid
|
Endogenous Metabolite
|
Metabolic Disease
|
|
p-Toluic acid (4-Methylbenzoic acid), coumarin, is a substituted benzoic acid. p-Toluic acidis synthetic p-aminomethylbenzoic acid (PAMBA), intermediates such as p-toluonitrile. p-Toluic acidMay have potential reproductive toxicity, press 1g/kgRepeated administration of doses can produce a variety of adverse effects on the epididymis .
|
-
- HY-153263
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
(Aminooxy)acetamide-Val-Cit-PAB-MMAE (MMAE 5) is an intermediate used in the synthetic preparation of drug-linker conjugates for ADC. (Aminooxy)acetamide-Val-Cit-PAB-MMAE is conjugated to polyamide via oxime bond formation to form MMAE polyamide conjugate. Then MMAE polyamide conjugate can be conjugated to Trastuzumab, to make ADC .
|
-
- HY-79576S2
-
|
Oestrone methyl ether-13C6; 3-O-Methylestrone-13C6
|
Isotope-Labeled Compounds
|
Others
|
|
Estrone 3-methyl ether- 13C6 is a 13C-labeled Estrone 3-methyl ether (HY-79576). Estrone 3-methyl ether (Oestrone methyl ether; 3-O-Methylestrone) is a synthetic intermediate useful for synthesis of estrogen receptor modulator .
|
-
- HY-175154
-
|
(1S,3S)-Benzyl-3-hydroxycyclopentanecarboxylate
|
Drug Intermediate
|
Others
|
|
(1S,3S)-3-Hydroxycyclopentane carboxylic acid benzyl ester ((1S,3S)-Benzyl-3-hydroxycyclopentanecarboxylate) is a synthetic intermediate. (1S,3S)-3-Hydroxycyclopentane carboxylic acid benzyl ester is useful for pharmaceutical synthesis.
|
-
- HY-185226
-
|
|
Drug Metabolite
|
Cancer
|
|
γ-Linolenic acid NHS ester is a lipid metabolite of γ-Linolenic acid (GLA) (HY-N7140), which can serve as a synthetic intermediate or probe labeling reagent for the preparation of GLA conjugates. In practical applications, γ-Linolenic acid NHS ester can be conjugated with taxanes and polysaccharides to form dual-type conjugates for drug delivery purposes .
|
-
- HY-W015012
-
|
|
Fluorescent Dye
|
Others
|
|
NBD-Hydrazine is an aldehyde- and ketone-reactive fluorescent probe. NBD-Hydrazine has excitation/emission maxima of 468/535 nm in the presence of aldehydes or ketones. NBD-Hydrazine can be used as a starting material to synthesize malondialdehyde-reactive fluorescent probes. NBD-Hydrazine is a synthetic intermediate in the synthesis of cupric and chronic ion colorimetric sensors .
|
-
- HY-W008388
-
|
N6-Benzoyladenosine
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
Bz-rA (N6-Benzoyladenosine) is a nucleoside derivative with an N6 protecting group. Bz-rA is mainly used as a synthetic intermediate to participate in photocatalytic oxidative cyclization reactions and synthesize oligoribonucleotides. Bz-rA can be used to efficiently construct heterocyclic skeletons in photochemical conversions and protect the ribose moiety to regulate the cyclization pathway .
|
-
- HY-47868
-
|
|
Drug Intermediate
|
Others
|
|
(S)-(2-Amino-5-methoxy-4-((triisopropylsilyl)oxy)phenyl)(6-(((tert-butyldimethylsilyl)oxy)methyl)-5-azaspiro[2.4]heptan-5-yl)methanone (compound 1-6) is a synthetic intermediate useful for pharmaceutical synthesis .
|
-
- HY-W003129
-
|
|
Drug Intermediate
Bacterial
|
Infection
|
|
2-Bromo-4-chloropyridine is a halogenated pyridine derivative that serves as a synthetic intermediate. 2-Bromo-4-chloropyridine undergoes Suzuki-Miyaura coupling with 4-tert-butylphenylboronic acid (HY-W007389). 2-Bromo-4-chloropyridine facilitates the construction of compounds with broad-spectrum antibacterial activity .
|
-
- HY-134349A
-
|
8-Piperidino-NAD+ sodium
|
Endogenous Metabolite
|
Others
|
|
8-PIP-NAD+ (sodium) (8-Piperidino-NAD+ (sodium)) is a derivative of the signaling molecule and enzyme cofactor NAD+ (HY-B0445). 8-PIP-NAD+ (sodium) can be used in the determination of poly(ADP-ribose) polymerase (PARP) target proteins. 8-PIP-NAD+ (sodium) is a synthetic intermediate in the synthesis of cyclic ADP-ribose (cADPR) derivatives .
|
-
- HY-W007273R
-
|
|
Biochemical Assay Reagents
Reference Standards
|
Endocrinology
|
|
11-Dodecyn-1-ol (Standard) is the analytical standard of 11-Dodecyn-1-ol (HY-W007273). This product is intended for research and analytical applications. 11-Dodecyn-1-ol is a synthetic intermediate of the sex pheromone (Z,E)-11,13,15-Hexadecatrienyl acetate for Thaumetopoea processionea .
|
-
- HY-W004121
-
|
|
Drug Intermediate
|
Cancer
|
|
4-Biphenylsulfonyl chloride is a synthetic intermediate that participates in the sulfonamide formation reaction to synthesize antiproliferative compounds. The derivatives of 4-Biphenylsulfonyl chloride inhibit human head and neck squamous cell carcinoma (HNSCC) cells by increasing PTEN expression and inhibiting the PI3K/Akt/mTOR pathway. 4-Biphenylsulfonyl chloride can be used in the development of anticancer drugs for HNSCC .
|
-
- HY-176068
-
|
|
Androgen Receptor
|
Cancer
|
|
3-Cl-Pyridine-amide-acrylaldehyde-piperazine is a synthetic intermediate of LO-4-25 (HY-176067). LO-4-25 is an androgen receptor (AR) DNA binding domain ligand linked via a linker to the truncated fumaramide handle. LO-4-25 shows robust degradation of both AR and AR-V7 in 22Rv1 cells .
|
-
- HY-W016689
-
|
|
Drug Intermediate
|
Cancer
|
|
2-Amino-4-phenylthiazole is a synthetic intermediate useful for pharmaceutical synthesis. 2-Amino-4-phenylthiazole can be used to synthesize suberoylanilide hydroxamic acid (SAHA) analogs with cancer cell growth inhibitory activities. 2-Amino-4-phenylthiazole also can be used to synthesize ketone histone deacetylase inhibitors with antitumor activity in vivo .
|
-
- HY-161703
-
|
|
Adenosine Deaminase
|
Cardiovascular Disease
|
|
2-Hydroxy-3′-O-methyladenosine is a synthetic intermediate product that can be used in the research of ischemic heart disease, cerebrovascular disease, kidney disease, inflammatory allergies and other diseases. 2-phenylamino-N6,2'-O-dimethyladenosine produced from 2-Hydroxy-3′-O-methyladenosine is an inhibitor of adenosine deaminase with a Ki of 13 nM .
|
-
- HY-32149S
-
-
- HY-137899
-
|
|
Endogenous Metabolite
|
Metabolic Disease
Cancer
|
|
Dephospho-CoA is a key intermediate in the biosynthesis of coenzyme A (CoA), which is catalyzed to form CoA by GTP-dependent Dephospho-CoA kinase (DPCK). Dephospho-CoA completes the final synthetic step of CoA via phosphorylation and participates in energy metabolism and cellular signal transduction. Dephospho-CoA can be used in studies involving cancer (e.g., regulation of cell proliferation) and metabolic diseases (e.g., mitochondrial dysfunction) .
|
-
- HY-76547R
-
|
4-Methylbenzoic acid (Standard)
|
Endogenous Metabolite
Reference Standards
|
Metabolic Disease
|
|
p-Toluic acid (Standard) is the analytical standard of p-Toluic acid. This product is intended for research and analytical applications. p-Toluic acid (4-Methylbenzoic acid), coumarin, is a substituted benzoic acid. p-Toluic acidis synthetic p-aminomethylbenzoic acid (PAMBA), intermediates such as p-toluonitrile. p-Toluic acidMay have potential reproductive toxicity, press 1g/kgRepeated administration of doses can produce a variety of adverse effects on the epididymis .
|
-
- HY-128753S6
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
Drug Intermediate
|
Metabolic Disease
|
|
D-Lyxose-d is the deuterium labeled D-Lyxose. D-Lyxose is an endogenous metabolite. D-Lyxose is a rare pentose sugar with significant potential for drug synthesis. D-Lyxose can be used as a starting material for anti-tumor drugs such as alpha galactose ceramide immunostimulants. D-Lyxose can be used as a precursor for L-nucleoside analogs for the development of antiviral drugs. D-Lyxose can be used as a synthetic intermediate for other rare sugars such as L-ribose .
|
-
- HY-79334R
-
|
|
Reference Standards
Endogenous Metabolite
|
Others
|
|
(S)-(+)-1,2-Propanediol (Standard) is the analytical standard of (S)-(+)-1,2-Propanediol. This product is intended for research and analytical applications. (S)-(+)-1,2-Propanediol is an endogenous metabolite. (S)-(+)-1,2-Propanediol can be used as an organic solvent and diluent in drug preparations. (S)-(+)-1,2-Propanediol can also be used as a chiral synthetic intermediate and a substrate for enzyme research.
|
-
- HY-128753S7
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
Drug Intermediate
|
Metabolic Disease
|
|
D-Lyxose-d-1 is the deuterium labeled D-Lyxose. D-Lyxose is an endogenous metabolite. D-Lyxose is a rare pentose sugar with significant potential for drug synthesis. D-Lyxose can be used as a starting material for anti-tumor drugs such as alpha galactose ceramide immunostimulants. D-Lyxose can be used as a precursor for L-nucleoside analogs for the development of antiviral drugs. D-Lyxose can be used as a synthetic intermediate for other rare sugars such as L-ribose .
|
-
- HY-W005485
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2,3,4,6-Tetra-O-benzyl-D-glucono-1,5-lactone
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Biochemical Assay Reagents
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Others
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Tetra-O-benzyl-δ-D-Gluconolactone (2,3,4,6-Tetra-O-benzyl-D-glucono-1,5-lactone) is a 1,5-sugar lactone and protected D-glucono-1,5-lactone, which serves as a synthetic intermediate in the field of carbohydrate chemistry. Tetra-O-benzyl-δ-D-Gluconolactone acts as a model substrate for zinc-mediated Barbier allylation, crotylation and propargylation reactions .
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- HY-125946
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Drug Intermediate
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Endocrinology
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Latanoprost lactone diol is a small organic molecule derived from Prostaglandin F2α (HY-12956), serving as a key synthetic intermediate and inactive metabolism-related form of Latanoprost (HY-B0577). Latanoprost lactone diol is significantly upregulated in hypothyroid rats, and its level can be reversed by crude polysaccharide, lactone and oligosaccharide fractions from the rhizome of Atractylodis macrocephalae. Latanoprost lactone diol can be used in studies related to hypothyroidism .
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- HY-128753S3
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Isotope-Labeled Compounds
Endogenous Metabolite
Drug Intermediate
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Others
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D-Lyxose- 13C-2 is the 13C labeled D-Lyxose. D-Lyxose is an endogenous metabolite. D-Lyxose is a rare pentose sugar with significant potential for drug synthesis. D-Lyxose can be used as a starting material for anti-tumor drugs such as alpha galactose ceramide immunostimulants. D-Lyxose can be used as a precursor for L-nucleoside analogs for the development of antiviral drugs. D-Lyxose can be used as a synthetic intermediate for other rare sugars such as L-ribose .
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- HY-128753S5
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Isotope-Labeled Compounds
Endogenous Metabolite
Drug Intermediate
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Others
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D-Lyxose- 13C-4 is the 13C labeled D-Lyxose. D-Lyxose is an endogenous metabolite. D-Lyxose is a rare pentose sugar with significant potential for drug synthesis. D-Lyxose can be used as a starting material for anti-tumor drugs such as alpha galactose ceramide immunostimulants. D-Lyxose can be used as a precursor for L-nucleoside analogs for the development of antiviral drugs. D-Lyxose can be used as a synthetic intermediate for other rare sugars such as L-ribose .
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- HY-128753R
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Reference Standards
Endogenous Metabolite
Drug Intermediate
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Metabolic Disease
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D-Lyxose (Standard) is the analytical standard of D-Lyxose. This product is intended for research and analytical applications. D-Lyxose is an endogenous metabolite. D-Lyxose is a rare pentose sugar with significant potential for drug synthesis. D-Lyxose can be used as a starting material for anti-tumor drugs such as alpha galactose ceramide immunostimulants. D-Lyxose can be used as a precursor for L-nucleoside analogs for the development of antiviral drugs. D-Lyxose can be used as a synthetic intermediate for other rare sugars such as L-ribose .
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- HY-128753S4
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Isotope-Labeled Compounds
Endogenous Metabolite
Drug Intermediate
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Others
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D-Lyxose- 13C-3 is the 13C labeled D-Lyxose. D-Lyxose is an endogenous metabolite. D-Lyxose is a rare pentose sugar with significant potential for drug synthesis. D-Lyxose can be used as a starting material for anti-tumor drugs such as alpha galactose ceramide immunostimulants. D-Lyxose can be used as a precursor for L-nucleoside analogs for the development of antiviral drugs. D-Lyxose can be used as a synthetic intermediate for other rare sugars such as L-ribose .
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- HY-W047688
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1-Boc-1,10-diaminodecane
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PROTAC Linkers
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Cancer
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tert-Butyl (10-aminodecyl) carbamate (1-Boc-1,10-diaminodecane) is a synthetic intermediate that serves as a PROTAC linker in PROTAC synthesis and other conjugation applications. tert-Butyl (10-aminodecyl) carbamate is an alkane chain with a terminal amine and a Boc-protected amino group. The amine group can react with carboxylic acids, active NHS esters, carbonyl groups (ketones, aldehydes), etc. The Boc group can be deprotected under mild acidic conditions to form a free amine .
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- HY-125946R
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Reference Standards
Drug Intermediate
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Metabolic Disease
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Latanoprost lactone diol (Standard) is the analytical standard of Latanoprost lactone diol (HY-125946). This product is intended for research and analytical applications. Latanoprost lactone diol is a small organic molecule derived from Prostaglandin F2α (HY-12956), and is a key synthetic intermediate and inactive metabolically related form of Latanoprost (HY-B0577). Latanoprost lactone diol is significantly upregulated in hypothyroid rats, and its levels can be reversed by the crude polysaccharide, lactone, and oligosaccharide components of the rhizome of Atractylodis macrocephalae. Latanoprost lactone diol can be used for research related to hypothyroidism.
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- HY-W001242
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- HY-W014159
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Biochemical Assay Reagents
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Others
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1-Bromo-2-methyl-3-nitrobenzene is an organic synthesis intermediate. 1-Bromo-2-methyl-3-nitrobenzene participates in chemical reactions such as electrophilic substitution and coupling through the bromine atom and nitro group in the molecule, and acts as a synthetic precursor. 1-Bromo-2-methyl-3-nitrobenzene can construct complex molecular structures by relying on the leaving property of bromine and the electron-withdrawing property of nitro group, and can be used in the synthesis of benzimidazole VISTA inhibitors in medicinal chemistry .
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- HY-Y0373
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Biochemical Assay Reagents
Drug Intermediate
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Infection
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tert-Butyl carbazate serves as a starting material for the preparation of heterocyclic and hydrazine derivatives. tert-Butyl carbazate undergoes coupling with aryl, heteroaryl, and alkenyl boronic acids to synthesize doubly protected monosubstituted hydrazines. Derivatives of tert-Butyl carbazate exhibit varying degrees of inhibitory activity against Gram-positive bacteria, Gram-negative bacteria, and various fungi .
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- HY-179728
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Amylin Receptor
CGRP Receptor
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Metabolic Disease
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Amylin agonist 1 (Example 239a) is a receptor 3 for pancreatic amyloid peptide (bAMY3R) agonist, and its EC50 for stimulating cAMP production in cells is 6.17 nM. Amylin agonist 1 is also a receptor for calcitonin (bCTR) agonist, with its EC50 being 8.58 nM. Amylin agonist 1 can be used for research on type 2 diabetes and obesity .
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| Cat. No. |
Product Name |
Type |
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- HY-W002603
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Biochemical Assay Reagents
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Benzyl piperazine-1-carboxylate is a synthetic intermediate that can be used in the research of melanocortin-4 (MC4) receptor antagonists .
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- HY-40146
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N-Boc-3-azetidinone
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Biochemical Assay Reagents
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tert-Butyl 3-oxoazetidine-1-carboxylate is a synthetic intermediate. tert-Butyl 3-oxoazetidine-1-carboxylate is used in the discovery and development of compounds targeting cancer and tuberculosis .
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- HY-75813
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Biochemical Assay Reagents
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2-Aminonicotinaldehyde is a synthetic intermediate. 2-Aminonicotinaldehyde can be used for the synthesis of 5-HT3 receptor antagonists, AKT inhibitors, and other compounds. 2-Aminonicotinaldehyde is applicable to research on depression and cancers (including hepatocellular carcinoma) .
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- HY-I0308
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Biochemical Assay Reagents
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1-Methyl-1H-pyrazole-4-boronic acid pinacol ester is an organic synthetic intermediate, which can be used to synthesize other active compounds .
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- HY-W008321
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Biochemical Assay Reagents
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6-Bromo-3,4-dihydro-1 (2H)-naphthalenone is a synthetic intermediate. 6-Bromo-3,4-dihydro-1 (2H)-naphthalenone can be used for the synthesis of 2-Benzyl-6-bromo-3,4-dihydro-1 (2H)-naphthalenone. 6-Bromo-3,4-dihydro-1 (2H)-naphthalenone can be applied to the development of hypoglycemic agents .
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- HY-76562
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Biochemical Assay Reagents
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Methyl 6-bromopicolinate is a synthetic intermediate used in the preparation of γ-secretase inhibitor library scaffolds .
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- HY-W005485
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2,3,4,6-Tetra-O-benzyl-D-glucono-1,5-lactone
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Biochemical Assay Reagents
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Tetra-O-benzyl-δ-D-Gluconolactone (2,3,4,6-Tetra-O-benzyl-D-glucono-1,5-lactone) is a 1,5-sugar lactone and protected D-glucono-1,5-lactone, which serves as a synthetic intermediate in the field of carbohydrate chemistry. Tetra-O-benzyl-δ-D-Gluconolactone acts as a model substrate for zinc-mediated Barbier allylation, crotylation and propargylation reactions .
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- HY-W001242
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Biochemical Assay Reagents
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1-(Tetrahydropyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester is a pharmaceutical intermediate used in the synthesis of naphthyl FXIa/PKa inhibitors .
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- HY-W007690
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- HY-Y0185
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Biochemical Assay Reagents
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4'-Nitroacetophenone is a nitroaromatic compound. 4'-Nitroacetophenone is an important organic synthetic intermediate, which can be used for the synthesis of other active compounds such as Chloramphenicol (HY-B0239) .
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- HY-W036733
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Biochemical Assay Reagents
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4-Hydroxy-4-methylcyclohexanone is a useful synthetic reagent extracted from patent JP2009022162A. 4-Hydroxy-4-methylcyclohexanone can be used to synthesize trans-4-amino-1-methylcyclohexanol which is intermediate of pharmaceutical synthesis .
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- HY-21629
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Biochemical Assay Reagents
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N-Boc-4-piperidinemethanol (Compound 4) is a synthetic intermediate. N-Boc-4-piperidinemethanol can be used for the preparation of Acetylcholinesterase inhibitors .
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- HY-40040
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Biochemical Assay Reagents
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(S)-1-Boc-3-methylpiperazine is a synthetic intermediate for indole-piperazine hybrid antimicrobial agent preparation. (S)-1-Boc-3-methylpiperazine can be used for research on bacterial infection and fungal infection .
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- HY-W009498
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Biochemical Assay Reagents
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2,5-Dibromo-4-methylpyridine is a synthetic pyridine derivative and serves as an important intermediate .
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- HY-69055
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Biochemical Assay Reagents
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7-Bromoisoquinoline is a brominated isoquinoline and synthetic precursor that constructs the isoquinoline functional group at the C17 position of target molecules. 7-Bromoisoquinoline serves as a key synthetic intermediate for the synthesis of cortistatin A-derived anti-angiogenic steroidal analogs (e.g., 7-tributylstannyl isoquinoline). 7-Bromoisoquinoline .
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- HY-W002616
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5-Bromooxindole
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Biochemical Assay Reagents
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5-Bromoindolin-2-one (5-Bromooxindole) is a synthetic intermediate. 5-Bromoindolin-2-one can be used for the synthesis of CDK2 inhibitors and antibacterial agents .
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- HY-W003601
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Biochemical Assay Reagents
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2-Bromo-4-fluoropyridine is a synthetic halogenated heterocyclic organic compound and a key intermediate in the pharmaceutical and agrochemical industries. 2-Bromo-4-fluoropyridine can be used to synthesize bioactive molecules through cross-coupling reactions, such as Suzuki coupling or Buchwald-Hartwig amination.
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- HY-W003129
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Biochemical Assay Reagents
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2-Bromo-4-chloropyridine is a halogenated pyridine derivative that serves as a synthetic intermediate. 2-Bromo-4-chloropyridine undergoes Suzuki-Miyaura coupling with 4-tert-butylphenylboronic acid (HY-W007389). 2-Bromo-4-chloropyridine facilitates the construction of compounds with broad-spectrum antibacterial activity .
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- HY-W000933
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- HY-41840
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Biochemical Assay Reagents
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D-Glucurono-6,3-lactone acetonide is a acetone-protected derivative of D-Glucurono-6,3-lactone (HY-41982) that can be used as a synthetic intermediate.
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- HY-44087
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Biochemical Assay Reagents
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Ethyl (E)-3-(1-pyrrolidinyl)crotonate is an organic synthetic intermediate of the enamine ester type. Ethyl (E)-3-(1-pyrrolidinyl)crotonate has a stable structure and strong reactivity, and is mainly used for the construction of heterocyclic compounds and drug molecules.
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- HY-W004121
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Biochemical Assay Reagents
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4-Biphenylsulfonyl chloride is a synthetic intermediate that participates in the sulfonamide formation reaction to synthesize antiproliferative compounds. The derivatives of 4-Biphenylsulfonyl chloride inhibit human head and neck squamous cell carcinoma (HNSCC) cells by increasing PTEN expression and inhibiting the PI3K/Akt/mTOR pathway. 4-Biphenylsulfonyl chloride can be used in the development of anticancer drugs for HNSCC .
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- HY-W014159
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Biochemical Assay Reagents
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1-Bromo-2-methyl-3-nitrobenzene is an organic synthesis intermediate. 1-Bromo-2-methyl-3-nitrobenzene participates in chemical reactions such as electrophilic substitution and coupling through the bromine atom and nitro group in the molecule, and acts as a synthetic precursor. 1-Bromo-2-methyl-3-nitrobenzene can construct complex molecular structures by relying on the leaving property of bromine and the electron-withdrawing property of nitro group, and can be used in the synthesis of benzimidazole VISTA inhibitors in medicinal chemistry .
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- HY-32149
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Biochemical Assay Reagents
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1-Bromo-3-iodobenzene is a biochemical reagent and an important organic synthetic intermediate. 1-Bromo-3-iodobenzene can be used for the synthesis of other active compounds .
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- HY-159053
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- HY-W002642
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2-Aminocyclopent-1-ene-1-carbonitrile
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Biochemical Assay Reagents
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2-Amino-1-cyclopentene-1-carbonitrile (2-Aminocyclopent-1-ene-1-carbonitrile) is an important and universal synthetic intermediate in organic chemistry.
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Product Name |
Target |
Research Area |
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- HY-P4192
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ADC Linker
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Cancer
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Fomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit .
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- HY-W040417
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PI3K
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Others
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Boc-L-cyclobutylglycine is a Boc-protected L-cyclic amino acid and synthetic intermediate in the preparation of purinyl quinazolinone PI3Kδ inhibitors .
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| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
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- HY-128753S6
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D-Lyxose-d is the deuterium labeled D-Lyxose. D-Lyxose is an endogenous metabolite. D-Lyxose is a rare pentose sugar with significant potential for drug synthesis. D-Lyxose can be used as a starting material for anti-tumor drugs such as alpha galactose ceramide immunostimulants. D-Lyxose can be used as a precursor for L-nucleoside analogs for the development of antiviral drugs. D-Lyxose can be used as a synthetic intermediate for other rare sugars such as L-ribose .
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- HY-32149S
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1-Bromo-3-iodobenzene-d4 is the deuterium labeled 1-Bromo-3-iodobenzene (HY-32149). 1-Bromo-3-iodobenzene is a biochemical reagent and an important organic synthetic intermediate. 1-Bromo-3-iodobenzene can be used for the synthesis of other active compounds .
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- HY-W007690S
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Pyridin-4-ol-d5 is the deuterium labeled Pyridin-4-ol (HY-W007690) . Pyridin-4-ol is a pyridinol and can be used as synthetic intermediate .
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- HY-79576S2
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Estrone 3-methyl ether- 13C6 is a 13C-labeled Estrone 3-methyl ether (HY-79576). Estrone 3-methyl ether (Oestrone methyl ether; 3-O-Methylestrone) is a synthetic intermediate useful for synthesis of estrogen receptor modulator .
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- HY-128753S7
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D-Lyxose-d-1 is the deuterium labeled D-Lyxose. D-Lyxose is an endogenous metabolite. D-Lyxose is a rare pentose sugar with significant potential for drug synthesis. D-Lyxose can be used as a starting material for anti-tumor drugs such as alpha galactose ceramide immunostimulants. D-Lyxose can be used as a precursor for L-nucleoside analogs for the development of antiviral drugs. D-Lyxose can be used as a synthetic intermediate for other rare sugars such as L-ribose .
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- HY-128753S3
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D-Lyxose- 13C-2 is the 13C labeled D-Lyxose. D-Lyxose is an endogenous metabolite. D-Lyxose is a rare pentose sugar with significant potential for drug synthesis. D-Lyxose can be used as a starting material for anti-tumor drugs such as alpha galactose ceramide immunostimulants. D-Lyxose can be used as a precursor for L-nucleoside analogs for the development of antiviral drugs. D-Lyxose can be used as a synthetic intermediate for other rare sugars such as L-ribose .
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- HY-128753S5
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D-Lyxose- 13C-4 is the 13C labeled D-Lyxose. D-Lyxose is an endogenous metabolite. D-Lyxose is a rare pentose sugar with significant potential for drug synthesis. D-Lyxose can be used as a starting material for anti-tumor drugs such as alpha galactose ceramide immunostimulants. D-Lyxose can be used as a precursor for L-nucleoside analogs for the development of antiviral drugs. D-Lyxose can be used as a synthetic intermediate for other rare sugars such as L-ribose .
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- HY-128753S4
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D-Lyxose- 13C-3 is the 13C labeled D-Lyxose. D-Lyxose is an endogenous metabolite. D-Lyxose is a rare pentose sugar with significant potential for drug synthesis. D-Lyxose can be used as a starting material for anti-tumor drugs such as alpha galactose ceramide immunostimulants. D-Lyxose can be used as a precursor for L-nucleoside analogs for the development of antiviral drugs. D-Lyxose can be used as a synthetic intermediate for other rare sugars such as L-ribose .
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| Cat. No. |
Product Name |
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Classification |
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- HY-151661
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L-azidovaline (CHA)
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Azide
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N3-L-Val-OH (CHA) is a click chemistry containing an azide group, a valine derivative. N3-L-Val-OH (CHA) can also be used as a synthetic intermediate for Valaciclovir (Valacyclovir) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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| Cat. No. |
Product Name |
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Classification |
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- HY-152656
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Nucleoside Analogs
Adenosine
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2-Hydrazinyl-adenosine is a synthetic intermediate. Derivatives of 2-Hydrazinyl-adenosine act as A2A adenosine receptor agonists. 2-Hydrazinyl-adenosine is used in the research of neurodegenerative diseases .
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- HY-161703
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Nucleoside Analogs
Adenosine
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2-Hydroxy-3′-O-methyladenosine is a synthetic intermediate product that can be used in the research of ischemic heart disease, cerebrovascular disease, kidney disease, inflammatory allergies and other diseases. 2-phenylamino-N6,2'-O-dimethyladenosine produced from 2-Hydroxy-3′-O-methyladenosine is an inhibitor of adenosine deaminase with a Ki of 13 nM .
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