6-Bromo-3-fluoropyridine-2-carbaldehyde

Cat. No.: HY-W058423 Purity: 99.92%: Data Sheet
COA

SDS
Handling Instructions
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6-Bromo-3-fluoropyridine-2-carbaldehyde (synthetic intermediate of Compound I-90) is a synthetic intermediate. 6-Bromo-3-fluoropyridine-2-carbaldehyde can be used in the synthesis of HPK1 inhibitors. 6-Bromo-3-fluoropyridine-2-carbaldehyde is applicable to research on immune diseases and hematological diseases.

For research use only. We do not sell to patients.

6-Bromo-3-fluoropyridine-2-carbaldehyde Chemical Structure

CAS No. : 885267-36-7

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
500 mg	In-stock	Estimated Time of Arrival: December 31
1 g	In-stock	Estimated Time of Arrival: December 31
5 g	In-stock	Estimated Time of Arrival: December 31
10 g	In-stock	Estimated Time of Arrival: December 31
25 g	In-stock	Estimated Time of Arrival: December 31
50 g	In-stock	Estimated Time of Arrival: December 31
100 g	In-stock	Estimated Time of Arrival: December 31
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MAP4K2/GCK MAP4K3/GLK MAP4K4/HGK MAP4K5/KHS1 MAP4K6/MINK1 MAP4K7/TNIK MAP4K1/HPK1

Biological Activity
Purity & Documentation
References
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Description

In Vitro

6-Bromo-3-fluoropyridine-2-carbaldehyde serves as a synthetic raw material for Compound I-90 (an HPK1 inhibitor)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

204.00

Formula

C₆H₃BrFNO

CAS No.

885267-36-7

Appearance

Solid

Color

White to light yellow

SMILES

FC1=CC=C(Br)N=C1C=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (490.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.9020 mL	24.5098 mL	49.0196 mL
5 mM	0.9804 mL	4.9020 mL	9.8039 mL
10 mM	0.4902 mL	2.4510 mL	4.9020 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.92%

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Data Sheet (270 KB) SDS (394 KB)

COA (246 KB) GC (270 KB)

Handling Instructions (2659 KB)

References

[1]. Gao, et al. Substituted pyrrolinone compounds. WO2025021181A1. WIPO (PCT). 2024-07-26.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.9020 mL	24.5098 mL	49.0196 mL	122.5490 mL
	5 mM	0.9804 mL	4.9020 mL	9.8039 mL	24.5098 mL
	10 mM	0.4902 mL	2.4510 mL	4.9020 mL	12.2549 mL
	15 mM	0.3268 mL	1.6340 mL	3.2680 mL	8.1699 mL
	20 mM	0.2451 mL	1.2255 mL	2.4510 mL	6.1275 mL
	25 mM	0.1961 mL	0.9804 mL	1.9608 mL	4.9020 mL
	30 mM	0.1634 mL	0.8170 mL	1.6340 mL	4.0850 mL
	40 mM	0.1225 mL	0.6127 mL	1.2255 mL	3.0637 mL
	50 mM	0.0980 mL	0.4902 mL	0.9804 mL	2.4510 mL
	60 mM	0.0817 mL	0.4085 mL	0.8170 mL	2.0425 mL
	80 mM	0.0613 mL	0.3064 mL	0.6127 mL	1.5319 mL
	100 mM	0.0490 mL	0.2451 mL	0.4902 mL	1.2255 mL