1. Anti-infection
  2. Fungal
    Antibiotic
  3. Pneumocandin B0

Pneumocandin B0 (Synonyms: L-688786)

Cat. No.: HY-17578 Purity: 97.21%
Handling Instructions

Pneumocandin B0(L-688786), a key intermediate in the synthesis of the antifungal agent, Cancidas, has led to the identification of several materials with potential for improved performance.

For research use only. We do not sell to patients.

Pneumocandin B0 Chemical Structure

Pneumocandin B0 Chemical Structure

CAS No. : 135575-42-7

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 217 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 217 In-stock
Estimated Time of Arrival: December 31
Solid
10 mg USD 185 In-stock
Estimated Time of Arrival: December 31
50 mg USD 550 In-stock
Estimated Time of Arrival: December 31
100 mg USD 950 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

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Description

Pneumocandin B0(L-688786), a key intermediate in the synthesis of the antifungal agent, Cancidas, has led to the identification of several materials with potential for improved performance.

Molecular Weight

1065.21

Formula

C50H80N8O17

CAS No.
SMILES

O=C([[email protected]](NC(C(NC([[email protected]@](C[[email protected]@H](O)C1)([H])N1C2=O)=O)[[email protected]](O)[[email protected]](C3=CC=C(O)C=C3)O)=O)([H])[[email protected]](O)CC(N)=O)N4[[email protected]@](C(N[[email protected]@H]([[email protected]@H](C[[email protected]@H](C(NC2[[email protected]](O)C)=O)NC(CCCCCCCC[[email protected]@H](C)C[[email protected]@H](C)CC)=O)O)O)=O)([H])[[email protected]@H](O)CC4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (93.88 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9388 mL 4.6939 mL 9.3878 mL
5 mM 0.1878 mL 0.9388 mL 1.8776 mL
10 mM 0.0939 mL 0.4694 mL 0.9388 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 4.55 mg/mL (4.27 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (2.35 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (2.35 mM); Clear solution

*All of the co-solvents are available by MCE.
References
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Product Name:
Pneumocandin B0
Cat. No.:
HY-17578
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