TP748
Based on 1 Customer Validation
TP748,an isoxazole, is a key intermediate for fully synthetic tetracyclines.
For research use only. We do not sell to patients.
- Purity: 99.14%
- CAS No.: 951698-15-0
- Formula: C15H18N2O2
- Molecular Weight:258.32
-
Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
A robust, cost effective and high yielding manufacturing process for enantiomerically enriched (S)-allylic amine 3, a key intermediate for fully synthetic tetracyclines have been developed[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 951698-15-0
-
Appearance Solid
-
Molecular Weight 258.32
-
Formula C15H18N2O2
-
Color White to off-white
-
SMILES
CN(C)[C@H](C1=CC(OCC2=CC=CC=C2)=NO1)C=C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (387.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (272 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8712 mL | 19.3558 mL | 38.7117 mL | 96.7792 mL |
| 5 mM | 0.7742 mL | 3.8712 mL | 7.7423 mL | 19.3558 mL | |
| 10 mM | 0.3871 mL | 1.9356 mL | 3.8712 mL | 9.6779 mL | |
| 15 mM | 0.2581 mL | 1.2904 mL | 2.5808 mL | 6.4519 mL | |
| 20 mM | 0.1936 mL | 0.9678 mL | 1.9356 mL | 4.8390 mL | |
| 25 mM | 0.1548 mL | 0.7742 mL | 1.5485 mL | 3.8712 mL | |
| 30 mM | 0.1290 mL | 0.6452 mL | 1.2904 mL | 3.2260 mL | |
| 40 mM | 0.0968 mL | 0.4839 mL | 0.9678 mL | 2.4195 mL | |
| 50 mM | 0.0774 mL | 0.3871 mL | 0.7742 mL | 1.9356 mL | |
| 60 mM | 0.0645 mL | 0.3226 mL | 0.6452 mL | 1.6130 mL | |
| 80 mM | 0.0484 mL | 0.2419 mL | 0.4839 mL | 1.2097 mL | |
| 100 mM | 0.0387 mL | 0.1936 mL | 0.3871 mL | 0.9678 mL |