2. GPCR/G Protein Neuronal Signaling
  3. Amylin Receptor CGRP Receptor
  4. Amylin agonist 1

Amylin agonist 1 (Example 239a) is a receptor 3 for pancreatic amyloid peptide (bAMY3R) agonist, and its EC50 for stimulating cAMP production in cells is 6.17 nM. Amylin agonist 1 is also a receptor for calcitonin (bCTR) agonist, with its EC50 being 8.58 nM. Amylin agonist 1 can be used for research on type 2 diabetes and obesity.

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Amylin agonist 1

Amylin agonist 1 Chemical Structure

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Amylin agonist 1 Related Antibodies

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Description

Amylin agonist 1 (Example 239a) is a receptor 3 for pancreatic amyloid peptide (bAMY3R) agonist, and its EC50 for stimulating cAMP production in cells is 6.17 nM. Amylin agonist 1 is also a receptor for calcitonin (bCTR) agonist, with its EC50 being 8.58 nM. Amylin agonist 1 can be used for research on type 2 diabetes and obesity[1].

Molecular Weight

645.15

Formula

C33H37ClN8O4
SMILES

CC(CC1=C(C(C2=CC=C3C(OCC(N3CC4=NC=C(C=N4)Cl)=O)=C2)=C5C=NN(C5=N1)C6CCN(CC6C)C7COC7)C(N)=O)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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Amylin agonist 1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Amylin agonist 1Amylin agonist1Amylin agonist-1Amylin ReceptorCGRP ReceptorAMYRCalcitonin gene-related peptide receptorCalcitonin receptor agonistPyrazolopyridine derivativeType 2 diabetesObesityMetabolic syndromePharmaceutical compositionSynthetic intermediateAgonist activityEC50GLP-1Combination therapyInhibitorinhibitorinhibit

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