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  4. 5-Bromoindolin-2-one

5-Bromoindolin-2-one  (Synonyms: 5-Bromooxindole)

Cat. No.: HY-W002616 Purity: 99.50%
COA
SDS
Handling Instructions Technical Support

5-Bromoindolin-2-one (5-Bromooxindole) is a synthetic intermediate. 5-Bromoindolin-2-one can be used for the synthesis of CDK2 inhibitors and antibacterial agents.

For research use only. We do not sell to patients.

5-Bromoindolin-2-one

5-Bromoindolin-2-one Chemical Structure

CAS No. : 20870-78-4

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
10 mM * 1 mL in DMSO In-stock
Solid
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Customer Review

Based on 1 publication(s) in Google Scholar

5-Bromoindolin-2-one Related Antibodies

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  • Purity & Documentation

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Description

5-Bromoindolin-2-one (5-Bromooxindole) is a synthetic intermediate. 5-Bromoindolin-2-one can be used for the synthesis of CDK2 inhibitors and antibacterial agents[1].

In Vitro

5-Bromoindolin-2-one serves as a building block for the synthesis of CDK2 inhibitors and antibacterial agents[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

5-Bromoindolin-2-one Related Antibodies
Molecular Weight

212.05

Formula

C8H6BrNO
CAS No.
Appearance

Solid

Color

Off-white to pink

SMILES

BrC1=CC=C(N2)C(CC2=O)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (471.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.7159 mL 23.5793 mL 47.1587 mL
5 mM 0.9432 mL 4.7159 mL 9.4317 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.50%

SDS (396 KB)

COA (246 KB) HNMR (115 KB) RP-HPLC (253 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.7159 mL 23.5793 mL 47.1587 mL 117.8967 mL
5 mM 0.9432 mL 4.7159 mL 9.4317 mL 23.5793 mL
10 mM 0.4716 mL 2.3579 mL 4.7159 mL 11.7897 mL
15 mM 0.3144 mL 1.5720 mL 3.1439 mL 7.8598 mL
20 mM 0.2358 mL 1.1790 mL 2.3579 mL 5.8948 mL
25 mM 0.1886 mL 0.9432 mL 1.8863 mL 4.7159 mL
30 mM 0.1572 mL 0.7860 mL 1.5720 mL 3.9299 mL
40 mM 0.1179 mL 0.5895 mL 1.1790 mL 2.9474 mL
50 mM 0.0943 mL 0.4716 mL 0.9432 mL 2.3579 mL
60 mM 0.0786 mL 0.3930 mL 0.7860 mL 1.9649 mL
80 mM 0.0589 mL 0.2947 mL 0.5895 mL 1.4737 mL
100 mM 0.0472 mL 0.2358 mL 0.4716 mL 1.1790 mL
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5-Bromoindolin-2-one Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-Bromoindolin-2-one20870-78-45-BromooxindoleDrug IntermediateDrug IintermediateAblIGF-1RKDRBacillus cereusGram-positive bacteriaRetc-MetCDK2PKASrcInhibitorinhibitorinhibit

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