4-Phenyl-2-pyrrolidinone

Cat. No.: HY-W017851 Purity: 99.93%: Data Sheet
COA

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Handling Instructions
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4-Phenyl-2-pyrrolidinone is a precursor and synthetic intermediate. 4-Phenyl-2-pyrrolidinone can be used as a precursor in the synthesis of compounds with anticonvulsant and nootropic activities and is an intermediate in the synthesis of bromodomain-containing protein 4 (BRD4) bromodomain 1 inhibitors.

For research use only. We do not sell to patients.

4-Phenyl-2-pyrrolidinone Chemical Structure

CAS No. : 1198-97-6

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
5 g	In-stock	Estimated Time of Arrival: December 31
10 g	In-stock	Estimated Time of Arrival: December 31
25 g	In-stock	Estimated Time of Arrival: December 31
50 g	In-stock	Estimated Time of Arrival: December 31
100 g	In-stock	Estimated Time of Arrival: December 31
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Biological Activity
Purity & Documentation
References
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Description

Molecular Weight

161.20

Formula

C₁₀H₁₁NO

CAS No.

1198-97-6

Appearance

Solid

Color

White to off-white

SMILES

O=C1NCC(C2=CC=CC=C2)C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (620.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.2035 mL	31.0174 mL	62.0347 mL
5 mM	1.2407 mL	6.2035 mL	12.4069 mL
10 mM	0.6203 mL	3.1017 mL	6.2035 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.93%

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Data Sheet (268 KB) SDS (393 KB)

COA (249 KB) HNMR (115 KB) RP-HPLC (213 KB)

Handling Instructions (2659 KB)

References

[1]. Zhmurenko L A, et al. Synthesis of 4-phenylpyrrolidone derivatives with anticonvulsant and nootropic activity[J]. Pharmaceutical Chemistry Journal, 2019, 53(5): 429-435.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	6.2035 mL	31.0174 mL	62.0347 mL	155.0869 mL
	5 mM	1.2407 mL	6.2035 mL	12.4069 mL	31.0174 mL
	10 mM	0.6203 mL	3.1017 mL	6.2035 mL	15.5087 mL
	15 mM	0.4136 mL	2.0678 mL	4.1356 mL	10.3391 mL
	20 mM	0.3102 mL	1.5509 mL	3.1017 mL	7.7543 mL
	25 mM	0.2481 mL	1.2407 mL	2.4814 mL	6.2035 mL
	30 mM	0.2068 mL	1.0339 mL	2.0678 mL	5.1696 mL
	40 mM	0.1551 mL	0.7754 mL	1.5509 mL	3.8772 mL
	50 mM	0.1241 mL	0.6203 mL	1.2407 mL	3.1017 mL
	60 mM	0.1034 mL	0.5170 mL	1.0339 mL	2.5848 mL
	80 mM	0.0775 mL	0.3877 mL	0.7754 mL	1.9386 mL
	100 mM	0.0620 mL	0.3102 mL	0.6203 mL	1.5509 mL