L-Allylglycine
Based on 1 publication(s) in Google Scholar
L-Allylglycine (L-2-Allylglycine) is an amino acid derivative. L-Allylglycine is an inhibitor for glutamate decarboxylase (GAD) that reduces the GABA biosynthesis in the brain. L-Allylglycine exhibits convulsant activity.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 16338-48-0
- Formula: C5H9NO2
- Molecular Weight:115.13
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) L-Allylglycine
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Customer Validation & Images
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WB
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Sprague-Dawley rats models[2].
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Dosage:150 mg/kg or 200 μg
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Administration:ip or intranigral injection, single dose
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Result:Reduced the GABA content in the hippocampus, cortex and cerebellum.
Induced running fits, partial rigidity, and convulsions in rats.
Chemical Information
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CAS No. 16338-48-0
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Appearance Solid
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Molecular Weight 115.13
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Formula C5H9NO2
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Color White to off-white
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Synonyms
L-2-Allylglycine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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J Biol Chem
Angiotensin-Converting Enzyme 2 improves hepatic insulin resistance by regulating GABAergic signaling in the liver. [Abstract]2022 Dec;298(12):102603. PMID: 36265585
L-Allylglycine purchased from MedChemExpress. Usage Cited in: J Biol Chem. 2022 Dec;298(12):102603. [Abstract]
The effect of ACE2-mediated up-regulation of AKT phosphorylation is almost blocked by (S)-2-Allylglycine (Ally) (5 mM; 24 h) in HepG2 cells.
Solvent & Solubility
H2O : 50 mg/mL (434.29 mM; Need ultrasonic)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 8.6858 mL | 43.4292 mL | 86.8583 mL | 217.1458 mL |
| 5 mM | 1.7372 mL | 8.6858 mL | 17.3717 mL | 43.4292 mL | |
| 10 mM | 0.8686 mL | 4.3429 mL | 8.6858 mL | 21.7146 mL | |
| 15 mM | 0.5791 mL | 2.8953 mL | 5.7906 mL | 14.4764 mL | |
| 20 mM | 0.4343 mL | 2.1715 mL | 4.3429 mL | 10.8573 mL | |
| 25 mM | 0.3474 mL | 1.7372 mL | 3.4743 mL | 8.6858 mL | |
| 30 mM | 0.2895 mL | 1.4476 mL | 2.8953 mL | 7.2382 mL | |
| 40 mM | 0.2171 mL | 1.0857 mL | 2.1715 mL | 5.4286 mL | |
| 50 mM | 0.1737 mL | 0.8686 mL | 1.7372 mL | 4.3429 mL | |
| 60 mM | 0.1448 mL | 0.7238 mL | 1.4476 mL | 3.6191 mL | |
| 80 mM | 0.1086 mL | 0.5429 mL | 1.0857 mL | 2.7143 mL | |
| 100 mM | 0.0869 mL | 0.4343 mL | 0.8686 mL | 2.1715 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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