NCS-382 sodium
Based on 1 publication(s) in Google Scholar
NCS-382 (sodium) is a potent GABA receptor antagonist. NCS-382 (sodium) has anti-sedative and anti-hypnotic activities and can be used in research related to neurological diseases.
For research use only. We do not sell to patients.
- Purity: 99.0%
- CAS No.: 131733-92-1
- Formula: C13H13NaO3
- Molecular Weight:240.23
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) NCS-382 sodium
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Biological Activity
Chemical Information
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CAS No. 131733-92-1
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Appearance Solid
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Molecular Weight 240.23
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Formula C13H13NaO3
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Color White to off-white
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SMILES
O=C(O[Na])/C=C1CCCC2=CC=CC=C2C\1O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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J Neuroinflammation
Sleep deprivation induces anxiety-like behaviors through IL-6 driven astrocyte-GABAergic neuron crosstalk in the PAG-ACC circuit. [Abstract]2026 May 22. PMID: 42174628
Solvent & Solubility
DMSO : ≥ 12 mg/mL (49.95 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.1627 mL | 20.8134 mL | 41.6268 mL | 104.0669 mL |
| 5 mM | 0.8325 mL | 4.1627 mL | 8.3254 mL | 20.8134 mL | |
| 10 mM | 0.4163 mL | 2.0813 mL | 4.1627 mL | 10.4067 mL | |
| 15 mM | 0.2775 mL | 1.3876 mL | 2.7751 mL | 6.9378 mL | |
| 20 mM | 0.2081 mL | 1.0407 mL | 2.0813 mL | 5.2033 mL | |
| 25 mM | 0.1665 mL | 0.8325 mL | 1.6651 mL | 4.1627 mL | |
| 30 mM | 0.1388 mL | 0.6938 mL | 1.3876 mL | 3.4689 mL | |
| 40 mM | 0.1041 mL | 0.5203 mL | 1.0407 mL | 2.6017 mL |