3-Cl-Pyridine-amide-acrylaldehyde-piperazine
Based on 1 Customer Validation
3-Cl-Pyridine-amide-acrylaldehyde-piperazine is a synthetic intermediate of LO-4-25 (HY-176067). LO-4-25 is an androgen receptor (AR) DNA binding domain ligand linked via a linker to the truncated fumaramide handle. LO-4-25 shows robust degradation of both AR and AR-V7 in 22Rv1 cells.
For research use only. We do not sell to patients.
- Purity: 99.30%
- Formula: C13H15ClN4O2
- Molecular Weight:294.74
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Storage:
4°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 294.74
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Formula C13H15ClN4O2
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Color White to off-white
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SMILES
O=C(NC1=CC(Cl)=CN=C1)/C=C/C(N2CCNCC2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (339.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3928 mL | 16.9641 mL | 33.9282 mL | 84.8205 mL |
| 5 mM | 0.6786 mL | 3.3928 mL | 6.7856 mL | 16.9641 mL | |
| 10 mM | 0.3393 mL | 1.6964 mL | 3.3928 mL | 8.4821 mL | |
| 15 mM | 0.2262 mL | 1.1309 mL | 2.2619 mL | 5.6547 mL | |
| 20 mM | 0.1696 mL | 0.8482 mL | 1.6964 mL | 4.2410 mL | |
| 25 mM | 0.1357 mL | 0.6786 mL | 1.3571 mL | 3.3928 mL | |
| 30 mM | 0.1131 mL | 0.5655 mL | 1.1309 mL | 2.8274 mL | |
| 40 mM | 0.0848 mL | 0.4241 mL | 0.8482 mL | 2.1205 mL | |
| 50 mM | 0.0679 mL | 0.3393 mL | 0.6786 mL | 1.6964 mL | |
| 60 mM | 0.0565 mL | 0.2827 mL | 0.5655 mL | 1.4137 mL | |
| 80 mM | 0.0424 mL | 0.2121 mL | 0.4241 mL | 1.0603 mL | |
| 100 mM | 0.0339 mL | 0.1696 mL | 0.3393 mL | 0.8482 mL |
3-Cl-Pyridine-amide-acrylaldehyde-piperazine Related Classifications
HY-176068 Related Classifications
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