117 Results for "

Y-{d-Trp}-GFM-NH2

" in MedChemExpress (MCE) Product Catalog:
Products (117)

117 Results for "Y-{d-Trp}-GFM-NH2" in MCE Product Catalog:

Cat. No.: HY-P3540
CAS No.: 73459-29-7
Research Areas:  

Others

Y-{d-Trp}-GFM-NH2 is an active peptide. Y-{d-Trp}-GFM-NH2 can be used for the research of various biochemical studies .
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16
16 Publications Verification
Cat. No.: HY-P0036
CAS No.: 83150-76-9
Synonyms: SMS 201-995
Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly [2].
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16
16 Publications Verification
Cat. No.: HY-17365
CAS No.: 79517-01-4
Synonyms: SMS 201-995 acetate
Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.
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6
6 Cited Publications
Cat. No.: HY-16381
CAS No.: 396091-73-9
Synonyms: SOM230
Target:  

Somatostatin Receptor

Research Areas:  

Endocrinology Cancer

Pasireotide (SOM230), a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively). Pasireotide can suppress GH, IGF-I and ACTH secretion, indicating potential efficacy in acromegaly and Cushing's disease. Pasireotide also exhibits antisecretory, antiproliferative, and proapoptotic activity [2] .
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4
4 Cited Publications
Cat. No.: HY-106244
CAS No.: 177943-88-3
Purity:  99.95%
Synonyms: Oxodotreotide
Research Areas:  

Cancer

DOTATATE is a DOTA-conjugated peptide. DOTATATE can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT) [2] . DOTATATE can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
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4
4 Cited Publications
Cat. No.: HY-106244A
CAS No.: 177943-89-4
Purity:  99.82%
Synonyms: Oxodotreotide acetate
Research Areas:  

Cancer

DOTATATE acetate is a DOTA-conjugated peptide. DOTATATE acetate can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT) [2] . DOTATATE (acetate) can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
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4
4 Cited Publications
Cat. No.: HY-P2161B
Target:  

Kisspeptin Receptor

Research Areas:  

Cancer

TAK-683 acetate is a potent full KISS1 receptor (KISS1R) agonist (IC50=170 pM) with improved metabolic stability. TAK-683 acetate is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC50 values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 acetate depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer [2] .
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2
2 Cited Publications
Cat. No.: HY-P0097
CAS No.: 158563-45-2
Synonyms: Melanostatine-5
Nonapeptide-1 (Melanostatine-5), a peptide hormone, is a selective antagonist of MC1R (Ki: 40 nM). Nonapeptide-1 is a competitive α-MSH antagonist that potently inhibits intracellular cAMP and melanosome dispersion induced by α-MSH in melanocytes (IC50: 2.5 nM and 11 nM, respectively). Nonapeptide-1 inhibits melanin synthesis, and can be used in the research of skin pigmentation and regulation of steroid production in the adrenal gland, skin cancer [2] .
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2
2 Cited Publications
Cat. No.: HY-P1335
CAS No.: 103429-32-9
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

CTAP is a potent, highly selective, and BBB penetrant μ opioid receptor antagonist, with an IC50 of 3.5 nM. CTAP displays over 1200-fold selectivity over δ opioid (IC50=4500 nM) and somatostatin receptors. CTAP can be used for the study of L-DOPA-induced dyskinesia (LID) and opiate overdose or addiction [2].
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2
2 Cited Publications
Cat. No.: HY-P1335A
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

CTAP TFA is a potent, highly selective, and BBB penetrant μ opioid receptor antagonist, with an IC50 of 3.5 nM. CTAP TFA displays over 1200-fold selectivity over δ opioid (IC50=4500 nM) and somatostatin receptors. CTAP TFA can be used for the study of L-DOPA-induced dyskinesia (LID) and opiate overdose or addiction [2].
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2
2 Cited Publications
Cat. No.: HY-16381A
CAS No.: 396091-76-2
Synonyms: SOM230 acetate
Target:  

Somatostatin Receptor

Research Areas:  

Endocrinology Cancer

Pasireotide (SOM230) acetate, a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively). Pasireotide acetate can suppress GH, IGF-I and ACTH secretion, indicating potential efficacy in acromegaly and Cushing's disease. Pasireotide acetate also exhibits antisecretory, antiproliferative, and proapoptotic activity [2] .
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1
1 Cited Publications
Cat. No.: HY-P0061A
CAS No.: 849479-74-9
Synonyms: RC-160 acetate; BMY-41606 acetate
Target:  

Neurokinin Receptor

Research Areas:  

Cancer

Vapreotide acetate (RC-160 acetate; BMY-41606 acetate) is a neurokinin-1 (NK1) receptor antagonist, with an IC50 of 330 nM.
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1
1 Cited Publications
Cat. No.: HY-P0061
CAS No.: 103222-11-3
Synonyms: RC160; BMY 41606
Target:  

Neurokinin Receptor

Research Areas:  

Cancer

Vapreotide is a neurokinin-1 (NK1) receptor antagonist, with an IC50 of 330 nM.
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1
1 Cited Publications
Cat. No.: HY-P1329A
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

CTOP TFA is a potent and highly selective μ-opioid receptor antagonist. CTOP TFA antagonizes the acute analgesic effect and hypermotility. CTOP TFA enhances extracellular dopamine levels in the nucleus accumbens. CTOP TFA dose-dependently enhances locomotor activity [2].
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1
1 Cited Publications
Cat. No.: HY-P1276A
Synonyms: Neurokinin-2 receptor antagonist TFA
Target:  

Neurokinin Receptor

Research Areas:  

Endocrinology

Men 10376 TFA is a selective tachykinin NK-2 receptor antagonist, with a Ki of 4.4 μM for rat small intestine NK-2 receptor .
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1
1 Cited Publications
Cat. No.: HY-P1206
CAS No.: 174688-78-9
Target:  

Somatostatin Receptor

Research Areas:  

Neurological Disease

CH 275 is a peptide analog of somatostatin and binds preferably to somatostatin receptor 1 (sst1) with a Ki of 52 nM . CH 275 acts as a potent and selective sst1 agonist (IC50=30.9 nM) and also displays IC50 values of 345 nM, >1 μM, >10 μM, >10 μM for human sst3, sst4, sst2 and sst5, respectively [2]. CH 275 can be used for the research of alzheimer’s disease .
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Cat. No.: HY-125586
CAS No.: 21150-22-1
Purity:  ≥96.0%
Research Areas:  

Cancer

β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs) [2].
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Cat. No.: HY-P4385
CAS No.: 129622-68-0
Target:  

PTHR

Research Areas:  

Metabolic Disease

(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) is a potent PTH-1R antagonist and does not display any partial agonist activity [2].
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Cat. No.: HY-P10920
CAS No.: 2415661-92-4
Target:  

Drug Derivative

Research Areas:  

Cancer

DOTAMTATE is a somatostatin analogue. DOTAMTATE marked 212Pb is promising for research of somatostatin receptor positive neuroendocrine tumors .
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Cat. No.: HY-P2426
CAS No.: 118102-98-0
Research Areas:  

Metabolic Disease

(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) is a potent and competitive antagonist of parathyroid hormone (PTH), with a Ki of 69 nM in bovine renal cortical membrane. (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) can be used for growth and development regulation [2].
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